Advances in Chemotherapy

List of Contributors

Preface

Systemic Control of Plant Nematodes

I. Introduction

II. Chemicals Mobile in Plants

III. Biochemistry of Nematode Disease

IV. Naturally Arising Resistance Factors

V. Chemotherapeutic Treatments

VI. Conclusions

References

The Cephalosporins

I. Introduction

II. History of the Cephalosporins

III. Cephalosporin P

IV. Penicillin N (Cephalosporin N) and Cephalosporin C

V. Conclusions

References

Metabolic Basis for the Actions of Analogs of Purines and Pyrimidines

I. Introduction

II. Mechanisms of Drug Action

III. Effects of Host on Drug; Drug Metabolism

IV. Effects of Drug on Host

V. Drugs, Parasites, and Hosts

VI. Conclusion

References

Olivomycin, Mithramycin, Chromomycin: Three Related Cancerostatic Antibiotics

I. Introduction

II. Microbiology, Chemistry, and Mode of Action

III. Pharmacology

IV. Antitumor Activity

V. Clinical Investigations

VI. Conclusions

References

Recent Advances in the Chemotherapy of Tuberculosis

I. Introduction

II. Modern Standard Therapy

III. The Roles of Sanatorium Treatment and Ambulatory Chemotherapy

IV. Isoniazid Alone

V. Thiacetazone (Thioacetazone)

VI. Intermittent Chemotherapy

VII. Reserve Regimens

VIII. Conclusion

References

Progress and Perspectives in the Chemotherapy of Acute Leukemia

I. Introduction

II. Past Progress in the Chemotherapy of Acute Leukemia

III. Current Research and Future Progress

References

Author Index

Subject Index