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Advances in Cancer Research
Genomics in Cancer Drug Discovery and Development
1st Edition - December 15, 2006
Editors: George F. Vande Woude, Garret Hampton, Karol Sikora, George Klein
Hardback ISBN:9780120066964
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eBook ISBN:9780080471013
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The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume stands as the first ever thematic… Read more
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The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume stands as the first ever thematic volume in the series, focusing on the topic of genomics in cancer drug development. The chapters included in this book represent the cutting-edge information in the field and span such topics as Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics; Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches; The Application of siRNA Technology to Cancer Biology Discovery; Ribozyme Technology for Cancer Gene Target Identification and Validation; Cancer Cell-Based Genomic and Small Molecule Screens; Tumour Antigens as Surrogate Markers and Targets for Therapy and Vaccines; Practices and Pitfalls of Mouse Cancer Models in Drug Discovery; Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development – Quantification of Emerging Protein Biomarkers; Molecular Optical Imaging of Therapeutic Targets of Cancer; Cancer Drug Approval in the United States, Europe and Japan.
Researchers and students in the basic and clinical science of cancer biology and oncology, plus related areas in genetics, immunology, pharmacology, cell biology and molecular biology.
Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics. Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches. The Application of siRNA Technology to Cancer Biology Discovery. Ribozyme Technology for Cancer Gene Target Identification and Validation. Cancer Cell-Based Genomic and Small Molecule Screens. Tumour Antigens as Surrogate Markers and Targets for Therapy and Vaccines. Practices and Pitfalls of Mouse Cancer Models in Drug Discovery. Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development – Quantification of Emerging Protein Biomarkers. Molecular Optical Imaging of Therapeutic Targets of Cancer. Cancer Drug Approval in the United States, Europe and Japan.
No. of pages: 432
Language: English
Published: December 15, 2006
Imprint: Academic Press
Hardback ISBN: 9780120066964
eBook ISBN: 9780080471013
GV
George F. Vande Woude
Affiliations and expertise
Director, Van Andel Research Institute, Grand Rapids, MI, USA
NCI-Frederick Cancer Research Facility Frederick, Maryland
ABL-Basic Research Program, NCI-Frederick Cancer Research and Development Center, Frederick, Maryland
GH
Garret Hampton
Affiliations and expertise
Celgene Signal Research, San Diego, CA, U.S.A.
KS
Karol Sikora
Affiliations and expertise
Professor, Hammersmith Hospital, Hammersmith, U.K.