Skip to main content

Advances in Cancer Research

Genomics in Cancer Drug Discovery and Development

  • 1st Edition, Volume 96 - December 15, 2006
  • Latest edition
  • Editors: George F. Vande Woude, Garret Hampton, Karol Sikora, George Klein
  • Language: English

The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume stands as the first ever themat… Read more

World Book Day celebration

Where learning shapes lives

Up to 25% off trusted resources that support research, study, and discovery.

Description

The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume stands as the first ever thematic volume in the series, focusing on the topic of genomics in cancer drug development. The chapters included in this book represent the cutting-edge information in the field and span such topics as Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics; Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches; The Application of siRNA Technology to Cancer Biology Discovery; Ribozyme Technology for Cancer Gene Target Identification and Validation; Cancer Cell-Based Genomic and Small Molecule Screens; Tumour Antigens as Surrogate Markers and Targets for Therapy and Vaccines; Practices and Pitfalls of Mouse Cancer Models in Drug Discovery; Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development – Quantification of Emerging Protein Biomarkers; Molecular Optical Imaging of Therapeutic Targets of Cancer; Cancer Drug Approval in the United States, Europe and Japan.

Readership

Researchers and students in the basic and clinical science of cancer biology and oncology, plus related areas in genetics, immunology, pharmacology, cell biology and molecular biology.

Table of contents

Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics.
Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches.
The Application of siRNA Technology to Cancer Biology Discovery.
Ribozyme Technology for Cancer Gene Target Identification and Validation.
Cancer Cell-Based Genomic and Small Molecule Screens.
Tumour Antigens as Surrogate Markers and Targets for Therapy and Vaccines.
Practices and Pitfalls of Mouse Cancer Models in Drug Discovery.
Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development – Quantification of Emerging Protein Biomarkers.
Molecular Optical Imaging of Therapeutic Targets of Cancer.
Cancer Drug Approval in the United States, Europe and Japan.

Product details

  • Edition: 1
  • Latest edition
  • Volume: 96
  • Published: December 15, 2006
  • Language: English

About the editors

GV

George F. Vande Woude

Affiliations and expertise
Director, Van Andel Research Institute, Grand Rapids, MI, USA NCI-Frederick Cancer Research Facility Frederick, Maryland ABL-Basic Research Program, NCI-Frederick Cancer Research and Development Center, Frederick, Maryland

GH

Garret Hampton

Affiliations and expertise
Celgene Signal Research, San Diego, CA, U.S.A.

KS

Karol Sikora

Affiliations and expertise
Professor, Hammersmith Hospital, Hammersmith, U.K.

GK

George Klein

Affiliations and expertise
Karolinska Insitutet, Stockholm, Sweden

View book on ScienceDirect

Read Advances in Cancer Research on ScienceDirect