Skip to main content

Advances in Amino Acid Mimetics and Peptidomimetics

  • 1st Edition, Volume 2 - December 20, 1999
  • Editor: A. Abell
  • Language: English
  • eBook ISBN:
    9 7 8 - 0 - 0 8 - 0 5 5 2 6 3 - 7

Peptidomimetics have found wide application as bioavailable, and often potent mimetics of natural peptides. They form the basis of important classes of enzyme inhibitors, they act… Read more

Advances in Amino Acid Mimetics and Peptidomimetics

Purchase options

Limited Offer

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code is needed.

Book bundle cover eBook and print

Institutional subscription on ScienceDirect

Request a sales quote
Peptidomimetics have found wide application as bioavailable, and often potent mimetics of natural peptides. They form the basis of important classes of enzyme inhibitors, they act as receptor agonists and antagonists, and they have even been used to mimic DNA structure. Recent advances in the use of solid-phase organic synthesis have paved the way for the preparation of libraries of these structures to allow the rapid optimization of theri biological properties and hence therapeutic potential. We are also beginning to gain a greater understanding of the structural features of this class of compounds that influence their ability to permeate membranes, and their rate of clearance and metabolism. This volume brings together many of these critical issues by highlighting recent advances in a number of core peptidomimetic-based research.