Advancements in Companion Animal Cardiology, An Issue of Veterinary Clinics of North America: Small Animal Practice

1st Edition - October 5, 2023

Editor: Joshua Stern

Hardback ISBN:

9 7 8 - 0 - 4 4 3 - 1 8 3 8 0 - 5

eBook ISBN:

9 7 8 - 0 - 4 4 3 - 1 8 3 8 1 - 2

In this issue of Veterinary Clinics: Small Animal Practice, guest editor Dr. Joshua Stern brings his considerable expertise to the topic of Advancements in Companion Animal… Read more

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In this issue of Veterinary Clinics: Small Animal Practice, guest editor Dr. Joshua Stern brings his considerable expertise to the topic of Advancements in Companion Animal Cardiology. Cardiovascular disease of companion animals has seen a boom in research productivity and novel therapies that make the future of cardiac care very bright. In this issue, top experts highlight advances in diagnosis and treatment for common cardiac diseases such as hypertrophic cardiomyopathy, mitral valve degeneration, and dilated cardiomyopathy.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Preface
The Role of Personalized Medicine in Companion Animal Cardiology
Key points
Introduction
Inherited cardiomyopathies
Pharmacogenetics in cardiology and cardiovascular therapy
Clinical Application of Pharmacogenetic-Guided Pharmacotherapy
Future directions
Summary
Clinics care points
Funding support
Disclosure
Predicting Development of Hypertrophic Cardiomyopathy and Disease Outcomes in Cats
Key points
Introduction
Predicting development of hypertrophic cardiomyopathy
Predicting cardiovascular events and mortality in cats with hypertrophic cardiomyopathy
Conclusion
Summary
Clinics care points
Conflict of interest declaration
Funding
Advancing Treatments for Feline Hypertrophic Cardiomyopathy: The Role of Animal Models and Targeted Therapeutics
Key points
Introduction
Animal models of hypertrophic cardiomyopathy
Future directions – focus on fibrosis
Novel drug therapies for treatment of hypertrophic cardiomyopathy
Summary
Clinics care points
Disclosures
Preventing Cardiogenic Thromboembolism in Cats: Literature Gaps, Rational Recommendations, and Future Therapies
Key points
Introduction
Current understanding of cardiogenic arterial thromboembolism pathophysiology
Knowledge gap
Risk assessment for cats with cardiomyopathies and diagnosis of cardiogenic arterial thromboembolism
Recommendations for preventing cardiogenic arterial thromboembolism
Thrombolytic therapy
Future therapies
Summary
Clinics care points
Disclosure
Hypertrophic Cardiomyopathy–Advances in Imaging and Diagnostic Strategies
Key points
Introduction
Discussion
Future directions
Summary
Clinics care points
Disclosure
Funding
Supplementary data
Mitral Valve Repair–The Development and Rise of Options in the Veterinary World
Key points
Introduction
Summary
Clinics care points
Disclosure
Supplementary data
Beyond Angiotensin-Converting Enzyme Inhibitors: Modulation of the Renin–Angiotensin–Aldosterone System to Delay or Manage Congestive Heart Failure
Key points
Introduction
Discussion
Future approaches to renin–angiotensin–aldosterone system modulation
Summary
Clinics care points
Disclosure
The Role of Autoantibodies in Companion Animal Cardiac Disease
Key points
Introduction/Background
Current evidence in veterinary cardiology
Discussion
Clinics care points
Disclosure
The Genetics of Canine Pulmonary Valve Stenosis
Key points
Introduction
Canine breed predispositions
Mode of inheritance
Human genetics
RASopathies
Additional syndromes associated with pulmonary valve stenosis
Transcription factors
Microdeletions and microduplications
Future genetic work
Summary
Clinics care points
Disclosure
Advances in the Treatment of Pulmonary Valve Stenosis
Key points
Background
Anatomy of pulmonary valve stenosis in dogs
Indications for pulmonary valve stenosis therapy
Therapeutic options for pulmonary valve stenosis
Balloon pulmonary valvuloplasty
High-pressure balloon pulmonary valvuloplasty
Cutting-balloon dilation for pulmonary valve dysplasia
Transpulmonary stent implantation
Summary
Clinics care points
Disclosure
Supplementary data
Treating Stubborn Cardiac Arrhythmias—Looking Toward the Future
Key points
Implantable cardioverter-defibrillator
Electrophysiological studies and catheter ablation
Three-dimensional electroanatomical mapping
Stereotactic arrhythmia radiotherapy
Summary
Disclosure
Supplementary data
The Role of Point-of-Care Ultrasound in Managing Cardiac Emergencies
Key points
Introduction
Image acquisition and recognizing normal anatomy
Severe left heart disease and left-sided congestive heart failure in dogs
Severe heart disease and congestive heart failure in cats
Severe right heart disease and right-sided congestive heart failure
Pericardial effusion and cardiac tamponade
Using point-of-care ultrasound to monitor cardiac emergencies
Summary
Clinics care points
Disclosure