Journals in Bioanalysis

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Journal of Chromatography A

• ISSN: 0021-9673
• 5 Year impact factor: 3.5
• Impact factor: 3.8

Journal of Chromatography A publishes research papers and critical reviews on all aspects of fundamental and applied separation science. The scope includes chromatography and related techniques (e.g. field-flow fractionation, electromigration techniques, hyphenated and other multi-dimensional techniques). Manuscripts on sample preparation methods/techniques and detection techniques, especially mass spectrometry are also considered, principally if they have a substantive chromatographic component. In addition, approaches dealing with the automation and miniaturization of separation techniques, and sample preparation and/or detection in combination with separation techniques are welcomed.Journal of Chromatography A values manuscripts describing fundamental research on all aspects of separation science theory and methodology, instrumental developments and analytical and preparative applications of general interest. In determining the suitability of submitted articles for publication, particular scrutiny is placed on the degree of novelty and significance of the research and the extent it adds to existing knowledge in separation science. Applications should address cutting-edge research questions and present a certain degree of complexity. The journal discourages submissions limited to the analysis of only one or two compounds or those that are straightforward extensions of published methods to new sample matrices. Furthermore, plagiarism and inadvertent lack of citations will be scrutinized extensively, and are a reason for immediate rejection.Journal of Chromatography A applies uniform acceptance criteria to all types of submissions (Full-length Research Papers; Short Communications; Technical Notes; Concept Papers; Review article; Discussions and Tutorials), irrespective of whether these are submitted to Regular Issues, Virtual Special Issues, or Virtual Symposium Special Issues.

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Journal of Chromatography B

• ISSN: 1570-0232
• 5 Year impact factor: 2.8
• Impact factor: 2.8

CHROMB (Journal of Chromatography B) publishes papers on developments in separation science relevant to biology and biomedical research including both fundamental advances and applications. Analytical techniques which may be considered include the various facets of chromatography, electrophoresis and related methods, affinity and immunoaffinity-based methodologies, hyphenated and other multi-dimensional techniques, and microanalytical approaches. The journal also considers articles reporting developments in sample preparation, detection techniques including mass spectrometry, and data handling and analysis.Developments related to preparative separations for the isolation and purification of components of biological systems may be published, including chromatographic and electrophoretic methods, affinity separations, field flow fractionation and other preparative approaches.Applications to the analysis of biological systems and samples will be considered when the analytical science contains a significant element of novelty, e.g. a new approach to the separation of a compound, novel combination of analytical techniques, or significantly improved analytical performance. Areas to be considered include:• The qualitative and quantitative analysis of biopolymers including proteins, monoclonal antibodies, peptides and their post-translational modifications as well as nucleic acids and glycans • The comparative analysis of biological systems using proteomics, genomics, metabolomics, lipidomics and other “omics” approaches • Clinical analysis, metabolism, therapeutic drug monitoring, toxicological analysis, doping analysis, veterinary applications, analysis of environmental contaminants in biological systems • The screening and profiling of body fluids, tissues, cells, biological matrices and systems, analysis of endogenous compounds, biomarkers • Identification of new bioactive compoundsApplications which utilize published or commercial analytical or preparative protocols with little or no modification or where the results of the application rather than the analytical methodology comprise the major element of novelty of the manuscript should be directed to more specialized journals. Modifications to a previously published method may be considered for a short communication in cases where the improvement in performance is significant. Reports of analytical methods for compounds in early pharmaceutical development often lack general interest and will not be published unless the authors can demonstrate the broader significance of the methodology involved. Quality control analyses of bulk drugs, natural products or pharmaceutical formulations of small molecules are not within scope.

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Journal of Pharmaceutical and Biomedical Analysis

• ISSN: 0731-7085
• 5 Year impact factor: 3.1
• Impact factor: 3.1

This journal is an international medium directed towards the needs of academic, clinical, government and industrial analysis by publishing original research reports and critical reviews on pharmaceutical and biomedical analysis. It covers the interdisciplinary aspects of analysis in the pharmaceutical, biomedical and clinical sciences, including developments in analytical methodology, instrumentation, computation and interpretation. Submissions on novel applications focusing on drug purity and stability studies, pharmacokinetics, therapeutic monitoring, metabolic profiling; drug-related aspects of analytical biochemistry and forensic toxicology; quality assurance in the pharmaceutical industry are also welcome.Studies from areas of well established and poorly selective methods, such as UV-VIS spectrophotometry (including derivative and multi-wavelength measurements), basic electroanalytical (potentiometric, polarographic and voltammetric) methods, fluorimetry, flow-injection analysis, etc. are accepted for publication in exceptional cases only, if a unique and substantial advantage over presently known systems is demonstrated. The same applies to the assay of simple drug formulations by any kind of methods and the determination of drugs in biological samples based merely on spiked samples. Drug purity/stability studies should contain information on the structure elucidation of the impurities/degradants.Papers dealing with the analytical aspects of traditional folk medicines are acceptable if the results are expected to attract the interest of readers also outside the area of origin, i.e. they have a focus on innovative analytical approaches. Regional differences in the phytochemical content of traditional folk medicine will not be considered. Manuscripts reporting on the analysis of novel phytochemicals will only be considered if their biological activity has been previously published in an international medium. Pharmacokinetic studies of traditional folk medicine will only be considered if only the identified components have been demonstrated to be solely responsible for the pharmacological activity.Bioanalytical papers (pharmacokinetic, bioequivalence, protein and DNA binding studies) are accepted if the focus is on innovative analytical methodology. Manuscripts describing the pharmacokinetic profile of a single compound will not be considered for review. Pharmacokinetic studies will only be considered if they offer new profiles of a drug(s) and its metabolite(s) or new understandings of the mechanisms in drug disposition or response of existing drugs. Analytical studies on new investigational drugs that are currently in the preclinical phase are only acceptable if their pharmacological activity is well documented in an international medium.Human subjects research must provide ethical approval and should include the name of the approving committee and the name of the institution and reference number where approval was granted. Animal studies must be approved from their Institutions Animal Care and Use Committee or any equivalent ethics committee accompanied by the reference number. For blood sampling procedures in rodents, retro-orbital bleeding will only be considered if a minimum of 7 days is allowed between repeat sampling. Furthermore, in the evaluation of the manuscript the editors reserve the right to determine whether the animal experimental technique is appropriate.In determining the suitability of submitted articles for publication, particular scrutiny will be placed on the degree of novelty and significance of the research and the extent to which it adds to existing knowledge in pharmaceutical and biomedical analysis. In all submissions to the journal, authors must address the question of how their proposed methodology compares with previously reported methods. A substantial body of work cannot be fractionated into different shorter papers.

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