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Thrombosis Research

  • ISSN: 0049-3848
  • 5 Year impact factor: 4.1
  • Impact factor: 3.7
Vascular Obstruction, Hemorrhage and Hemostasis Affiliated journal to the North American Thrombosis Forum (NATF) and the Hemostasis and Thrombosis Research Society (HTRS)Thrombosis Research is an international journal with a goal of rapid dissemination of new information on thrombosis, hemostasis, and vascular biology to advance science and clinical care. The journal publishes peer-reviewed original research, along with reviews, editorials, and opinions and critics. Both basic and clinical studies are published. Publication of research which will lead to novel approaches in diagnosis, therapy, prognosis and prevention of thrombotic and hemorrhagic diseases is given high priority.
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Thrombosis Research

Tissue and Cell

  • ISSN: 0040-8166
  • 5 Year impact factor: 2.5
  • Impact factor: 2.7
Tissue and Cell is devoted to original research on the organization of cells, subcellular and extracellular components at all levels, including the grouping and interrelations of cells in tissues and organs. The journal encourages submission of ultrastructural studies that provide novel insights into structure, function and physiology of cells and tissues, in health and disease. Bioengineering and stem cells studies focused on the description of morphological and/or histological data are also welcomed.Studies investigating the effect of compounds and/or substances on structure of cells and tissues are generally outside the scope of this journal. For consideration, studies should contain a clear rationale on the use of (a) given substance(s), have a compelling morphological and structural focus and present novel incremental findings from previous literature.
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Tissue and Cell

Topics in Companion Animal Medicine

  • ISSN: 1938-9736
  • 5 Year impact factor: 1.3
  • Impact factor: 1.3
As of January 2018, Topics in Companion Animal Medicine is no longer solely publishing solicited special themed issues. Please feel free to submit your research for the Editor-in-Chief's consideration. Published quarterly, Topics in Companion Animal Medicine is a peer-reviewed veterinary scientific journal dedicated to providing practitioners with the most recent advances in companion animal medicine. The journal publishes high quality original clinical research focusing on important topics in companion animal medicine. Topics in Companion Animal Medicine also features comprehensive review articles on topics of clinical interest, short communications, case reports/case series, and timely editorials addressing issues of interest to companion animal practitioners.
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Topics in Companion Animal Medicine

Toxicology

  • ISSN: 0300-483X
  • 5 Year impact factor: 4.4
  • Impact factor: 4.8
Affiliated with the German Toxicology SocietyToxicology as a multidisciplinary, data-rich field has witnessed the availability of a cutting-edge technologies to investigate mechanisms underlying adverse consequences of exposures to xenobiotic chemicals, particularly as it relates to human health. Toxicology fully embraces these advancements by serving as a hub for exchange of information regarding state-of-the-art developments in the broad field of contemporary toxicology. Journal scope emphasis is on human-relevant and mechanistic research at all levels of biological organization, ranging from the molecular scale to the organismal level. The publication priority for Toxicology is on original high-quality research and review papers on any topic relevant to toxicology, in particular related to hazard identification, all that are subject to rigorous peer-review. The Toxicology target audience includes undergraduates to full professionals in academic, industrial and regulatory settings in any part of the world.Notes from the EditorsIn order to support interpretation of published findings to human health, the journal requires inclusion of specific statements within the ABSTRACT and METHODS sections of each submitted article:ABSTRACT:The experimental system (e.g., in vivo species, cell culture, etc.) including the exposure dose or concentration and duration that produces an effect, if an effect is observed, must be described in the ABSTRACT to the manuscript.MATERIALS AND METHODS:The relevance of the experimental system and exposure dose or concentration and duration in terms of potential human exposures must be described in the Materials and Methods section of the manuscript. Justification of the exposure cannot be based solely on previous publications, but rather the comparison must be to either estimated, anticipated, or measured human exposures.The authors must identify the chemicals by CAS number, their source and purity; the method of randomization for group sampling, the number of experimental sample replicates in each treatment group, and provide a proper description of the statistical analysis of data that was employed.Journal Policy:TOXICOLOGY does not publish results from exposures to uncharacterized chemical mixtures or extracts from natural products. All exposures must be fully characterized analytically. Justification for this policy is that it is near impossible for other investigators to replicate findings of a study wherein the chemical composition of the exposure is not completely characterized.TOXICOLOGY does not publish purely descriptive safety studies or studies describing the therapeutic efficacy of cytotoxic agents without strong emphasis on end-points relating to a proposed mechanism of toxicity.
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Toxicology

Toxicology Letters

  • ISSN: 0378-4274
  • 5 Year impact factor: 3.2
  • Impact factor: 2.9
Official Journal of EUROTOXAffiliated with Austrian Society of ToxicologyAn international journal for the rapid publication of novel reports on a range of aspects of toxicology, especially mechanisms of toxicity.Toxicology Letters serves as a multidisciplinary forum for research in toxicology. The prime aim is the rapid publication of research studies that are both novel and advance our understanding of a particular area. In addition to hypothesis-driven studies on mechanisms of mammalian toxicity, Toxicology Letters welcomes seminal work in the following areas:In silico toxicologyToxicokineticsPhysiologically-based pharmacokinetic (PBPK) modelingSystems toxicologyPredictive toxicology3R research in toxicologyNew approach methodology (NAMs)Adverse outcome pathways (AOPs)Integrated testing strategiesSystematic and narrative reviews and mini-reviews in various areas of toxicology will be published. Clinical, occupational and safety evaluation, hazard and risk assessment, regulatory toxicology, impact on man, animal and environment studies of sufficient novelty to warrant rapid publication will be considered. Toxicology Letters also publishes editorials, commentaries and contemporary issues in toxicology.The following types of work are not within the scopes of Toxicology Letters:Ecotoxicology studiesCase studiesChemoprevention studiesPharmacological investigationsAuthors are advised to follow the ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments; https://arriveguidelines.org/) and the OECD guidance document on Good In Vitro Method Practices (GIVIMP; https://www.oecd.org/env/guidance-document-on-good-in-vitro-method-practices-givimp-9789264304796-en.htm). In vitro or in vivo investigations conducted at concentrations or doses of no relevance to human or animal exposure will not be considered. Routes of exposure other than those relevant to human or animal exposure need to be justified. Assessment of dose-response should be an integral component of any toxicological research report. Unless adequately justified, studies conducted at a single dose level may not be considered. Test materials must be chemically defined and characterized. Investigations of chemically undefined plant extracts or uncharacterized nanoparticles will not be considered.
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Toxicology Letters

Toxicology and Applied Pharmacology

  • ISSN: 0041-008X
  • 5 Year impact factor: 3.6
  • Impact factor: 3.3
Toxicology and Applied Pharmacology publishes original scientific research of relevance to animals or humans pertaining to the action of chemicals, drugs, or chemically-defined natural products.Regular articles address mechanistic approaches to physiological, pharmacologic, biochemical, cellular, or molecular understanding of toxicologic/pathologic lesions and to methods used to describe these responses. Safety Science articles address outstanding state-of-the-art preclinical and human translational characterization of drug and chemical safety employing cutting-edge science. Highly significant Regulatory Safety Science articles will also be considered in this category. Papers concerned with alternatives to the use of experimental animals are encouraged.Short articles report on high impact studies of broad interest to readers of TAAP that would benefit from rapid publication. These articles should contain no more than a combined total of four figures and tables. Authors should include in their cover letter the justification for consideration of their manuscript as a short article.TAAP also issues a standing call for outstanding Invited Review Articles. Potential authors should contact the Editor-In-Chief and complete an Invited Review Proposal Form before preparing or submitting their Review Article.Benefits to authors We also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our Support Center
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Toxicology and Applied Pharmacology

Toxicology in Vitro

  • ISSN: 0887-2333
  • 5 Year impact factor: 2.8
  • Impact factor: 2.6
Affiliated with the American Association for Cellular and Computational Toxicology and the European Society for Toxicology in Vitro.Toxicology in Vitro publishes original research papers, reviews and workshop reports focusing on the application and use of in vitro and in silico systems for toxicological evaluations (collectively described as New Approach Methodologies (NAM)). This includes the utilisation or the development of NAMs for assessing the potential adverse effects of chemicals for human safety assessment. In vitro techniques include primary cells, tissue slices, cell lines and stem cells (adult, embryonic and induced Pluripotent cells) or subcellular preparations thereof. Our journal strongly supports the Reduction, Refinement and Replacement (3R) of animals in toxicology evaluations.This is a wide topic and thus we have certain preferences including:Development of in vitro techniques and their application to research and regulatory use (i.e. 3R principle.Mechanistic underpinning of data.Ability to translate outcome to human safety assessment.We strongly encourage :The use of normal (non-transformed) human cells (where appropriate).Reporting the Short Tandem Repeat (STR) profile of the cells used (especially when cells have been provided as a gift or generated in house).Free access to raw (or primary) data.Appropriate model characterisation.The use (or reduction) of animal free components, including serum. [Especially when the system was already developed under such conditions, such as the HK-2 cell line].Attention to detailed methodology and appropriate statistics. [Readers need to know how you did the experiment, how many times, how many replicates etc?]Reporting the source of the compounded tested, catalogue no. and lot no. Where the chemical has been purified or synthesised a full analytical report is expected.Quantification of compounds in exposure medium and/or cells over time (biokinetics).We do not accept solely in vivo investigations and rarely accept animal in vivo, in vitro hybrid papers, except where the animal data was critical in the interpretation or validation of the in vitro data (and not merely confirmatory).We generally discourage investigations relating:Unidentified mixtures - for example in plant extracts.Solely pharmacological investigations (e.g. demonstrating your chemical kills cancer cells in vitro is not generally acceptable).Use of non-human cells when human equivalents exist and are available.The lack of adherence to established protocols, without direct explanation.Reporting cytotoxicity alone, with no mechanistic underpinning and/or no estimation of chemical exposure.
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Toxicology in Vitro

Toxicon

  • ISSN: 0041-0101
  • 5 Year impact factor: 2.7
  • Impact factor: 2.6
Toxicon is affiliated with The Brazilian Society of Toxinology, The International Society on Toxinology and The North American Society of Toxinology.Toxicon is dedicated to all areas related to natural toxins and publishes peer-reviewed manuscripts describing novel findings of broad interest and importance to the toxinology community.Articles that further the understanding and knowledge of toxinology are particularly welcomed, as are review articles on toxinology. Submissions on Toxinology, Pharmacology, Immunology, Biochemistry, Health, Genetics and Molecular Biology (General) are particularly welcomed.The journal publishes articles on the following topics:original research on toxins derived from animals, plants or microorganismsnovel findings related to the chemical, pharmacological, toxicological or immunological properties of natural toxinsmolecular biological studies of toxins and related genes from poisonous and venomous organisms that advance understanding of the role or function of toxinsthe use of toxins as tools in studying biological processesthe translational application of toxins, for example as pharmacological tools, drugs or insecticidesvenom and antivenom issuesclinical observations on poisoning and envenoming where a new therapeutic principle has been proposed or a decidedly superior clinical result has been obtainedepidemiological studies on envenoming or poisoning, provided they highlight a previously unrecognized medical problem or provide insight into the prevention or medical treatment of envenoming or poisoningproperly designed prospective community-based surveysToxicon does not accept submissions on retrospective surveys of hospital records, especially those lacking species identification, or articles describing well-known activities of venoms, such as antibacterial, anticancer or analgesic activities, without any attempt to define the mechanism of action or purify the active component(s).
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Toxicon

Transfusion and Apheresis Science

  • ISSN: 1473-0502
  • 5 Year impact factor: 1.4
  • Impact factor: 1.4
Official Journal of the World Apheresis Association, Turkish Society of Apheresis, European Society for Haemapheresis and Società Italiana di Emaferesi e Manipolazione CellulareTransfusion and Apheresis Science brings comprehensive and up-to-date information to physicians and health care professionals involved in the rapidly changing fields of transfusion medicine, hemostasis and apheresis. The journal presents original articles relating to scientific and clinical studies in the areas of immunohematology, transfusion practice, bleeding and thrombotic disorders and both therapeutic and donor apheresis including hematopoietic stem cells. Topics covered include the collection and processing of blood, compatibility testing and guidelines for the use of blood products, as well as screening for and transmission of blood-borne diseases. All areas of apheresis - therapeutic and collection - are also addressed. We would like to specifically encourage allied health professionals in this area to submit manuscripts that relate to improved patient and donor care, technical aspects and educational issues. Transfusion and Apheresis Science features a "Theme" section which includes, in each issue, a group of papers designed to review a specific topic of current importance in transfusion and hemostasis for the discussion of topical issues specific to apheresis and focuses on the operators' viewpoint. Another section is "What's Happening" which provides informal reporting of activities in the field. In addition, brief case reports and Letters to the Editor, as well as reviews of meetings and events of general interest, and a listing of recent patents make the journal a complete source of information for practitioners of transfusion, hemostasis and apheresis science. Immediate dissemination of important information is ensured by the commitment of Transfusion and Apheresis Science to rapid publication of both symposia and submitted papers.
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Transfusion and Apheresis Science

Transplant Immunology

  • ISSN: 0966-3274
  • 5 Year impact factor: 1.5
  • Impact factor: 1.6
Transplant Immunology will publish up-to-date information on all aspects of the broad field it encompasses. The journal is directed to general scientific and medical audience but in particular to basic and applied scientists, transplant-related laboratory personnel, transplant physicians and surgeons. The journal will present research reports and clinical data on all immunological aspects of organ-, tissue-, and haematopoietic stem cell transplantation. Furthermore, the journal is interested to publish high quality basic and clinical research in immunology, physiology and pathophysiology related to processes and diseases affecting transplant patients. Original papers, Brief reports, Cases reports and Review articles and Hypotheses will be considered for publication. Submitted manuscripts will be rapidly peer-reviewed and published. They will be judged on the basis of scientific merit, originality, timeliness and quality.
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Transplant Immunology

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