Chemistry of 2-Oxoaldehydes and 2-Oxoacids offers complete coverage on 2-oxoaldehydes and 2-oxoacid, which to date have not been covered in a comprehensive manner. Novel reactions related to 2-oxoaldehydes and 2-oxoacids on keto and aldehydic groups (both participating separately or in combination), decarboxylative reactions, spectral analysis and diverse applications are explored. The book is divided into two parts, with the first outlining methods for the preparation and physical properties of 2-Oxoaldehydes, along with the structure, spectral characteristics and reactivity of 2-Oxoaldehydes. The second part covers the preparation and physical properties of 2-Oxoacids and the synthesis of many related reactions. This book is essential reading for researchers working on these types of reactions in organic chemistry, medicinal chemistry, natural product chemistry and pharmaceutical chemistry.
Autonomic dysfunction is one of the most prevalent non-motor symptoms that occurs in Parkinson’s disease. Autonomic Dysfunction in Parkinson's Disease provides up to date information on this important topic, which affects quality of life of these patients. This include a large number of domains: orthostatic hypotension, excessive sweating, dry eyes, constipation, weight loss, increased sensitivity to heat and cold, sexual dysfunction.
Energy Methods and Finite Element Techniques: Stress and Vibration Applications provides readers with a complete understanding of the theory and practice of finite element analysis using energy methods to better understand, predict, and mitigate static stress and vibration in different structural and mechanical configurations. It presents readers with the underlying theory, techniques for implementation, and field-tested applications of these methods using linear ordinary differential equations. Statistical energy analysis and its various applications are covered, and applications discussed include plate problems, bars and beams, plane strain and stress, 3D elasticity problems, vibration problems, and more. Higher order plate and shell elements, steady state heat conduction, and shape function determinations and numerical integration are analyzed as well.
The subject of information geometry blends several areas of statistics, computer science, physics, and mathematics. The subject evolved from the groundbreaking article published by legendary statistician C.R. Rao in 1945. His works led to the creation of Cramer-Rao bounds, Rao distance, and Rao-Blackawellization. Fisher-Rao metrics and Rao distances play a very important role in geodesics, econometric analysis to modern-day business analytics. The chapters of the book are written by experts in the field who have been promoting the field of information geometry and its applications.
Cavitation and Bubble Dynamics: Fundamentals and Applications examines the latest advances in the field of cavitation and multiphase flows, including associated effects such as material erosion and spray instabilities. This book tackles the challenges of cavitation hindrance in the industrial world, while also drawing on interdisciplinary research to inform academic audiences on the latest advances in the fundamentals. Contributions to the book come from a wide range of specialists in areas including fuel systems, hydropower, marine engineering, multiphase flows and computational fluid mechanics, allowing readers to discover novel interdisciplinary experimentation techniques and research results. This book will be an essential tool for industry professionals and researchers working on applications where cavitation hindrance affects reliability, noise, and vibrations.
Reliability Analysis and Asset Management of Engineering Systems explains methods that can be used to evaluate reliability and availability of complex systems, including simulation-based methods. The increasing digitization of mechanical processes driven by Industry 4.0 increases the interaction between machines and monitoring and control systems, leading to increases in system complexity. For those systems the reliability and availability analyses are increasingly challenging, as the interaction between machines has become more complex, and the analysis of the flexibility of the production systems to respond to machinery failure may require advanced simulation techniques. This book fills a gap on how to deal with such complex systems by linking the concepts of systems reliability and asset management, and then making these solutions more accessible to industry by explaining the availability analysis of complex systems based on simulation methods that emphasise Petri nets.
Silicon-Based Hybrid Nanoparticles: Fundamentals, Properties, and Applications focuses on the fundamental principles and promising applications of silicon-based hybrid nanoparticles in nanoelectronics, energy storage/conversion, catalysis, sensors, biomedicine, environment and imaging. This book is an important reference source for materials scientists and engineers who are seeking to understand more about the major properties and applications of silicon-based hybrid nanoparticles. As the hybridization of silicon nanoparticles with other semiconductors or metal oxides nanoparticles may exhibit superior features, when compared to lone, individual nanoparticles, this book provides the latest insights. In addition, the silicon/iron oxide hybrid nanoparticles also possess excellent fluorescence, super-paramagnetism, and biocompatibility that can be effectively used for the diagnostic imaging system in vivo. Similarly, gold-silicon nanohybrids could be used as highly efficient near-infrared hyperthermia agents for cancer cell destruction.
Biopolymeric Nanomaterials: Fundamentals and Applications outlines the fundamental design concepts and emerging applications of biopolymeric nanomaterials. The book also provides information on emerging applications of biopolymeric nanomaterials, including in biomedicine, manufacturing and water purification, as well as assessing their physical, chemical and biological properties. This is an important reference source for materials scientists, engineers and biomedical scientists who are seeking to increase their understanding of how polymeric nanomaterials are being used for a range of biomedical and industrial applications. Biopolymeric nanomaterials refer to biocompatible nanomaterials, consisting of biopolymers, such as protein (silk, collagen, gelatin, β-casein, zein, and albumin), protein-mimicked polypeptides and polysaccharides (chitosan, alginate, pullulan, starch, and heparin). Biopolymeric nanomaterials may be used as i) delivery systems for bioactive compounds in food application, (ii) for delivery of therapeutic molecules (drugs and genes), or for (iii) tissue engineering.
The Alkaloids, Volume 86, is the newest release in a series that has covered the topic for more than 60 years. As the esteemed, leading reference in the field of alkaloid chemistry, this series covers all aspects of alkaloids, including their chemistry, biology and pharmacology. Sections are presented as high-quality, timeless reviews written by renowned experts in the field.
Foamability of Thermoplastic Polymeric Materials presents a cutting-edge approach to thermoplastic polymeric foams, drawing on the latest research and guiding the reader through the fundamental science, foamability, structure-property-processing relationship, multi-phase polymeric materials, degradation characteristics of biodegradable foams and advanced applications. Sections provide detailed information on foam manufacturing technologies and the fundamental science behind foaming, present insights on the factors affecting foamability, cover ways of enhancing the foamability of various polymeric materials, with special focus on multi-phase systems, discuss the degradation of biodegradable foams and special morphology development for scaffolds, packaging, acoustic and super-insulation applications, as well as cell seeding studies in scaffolds. Each application has specific requirements in terms of desired properties. This in-depth coverage and analysis helps those looking to move forward with microcellular processing and polymer foaming. This is an ideal resource for researchers, advanced students and professionals interested in the microcellular processing of polymeric materials in the areas of polymer foaming, polymer processing, plastics engineering and materials science.