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Elsevier

Books in Biomathematics

  • Handbook of MRI Pulse Sequences

    • 2nd Edition
    • Xiaohong Joe Zhou + 4 more
    • English
    Handbook of MRI Pulse Sequences, Second Edition includes 92 self-contained sections, with each section focusing on a single subject. A new section on detailing the advanced pulse sequence techniques covers a variety of basic and advanced image reconstruction methods. The extensive topic coverage and cross-referencing makes this book ideal for beginners learning the building blocks of MRI pulse sequence design, as well as for experienced professionals who are seeking deeper knowledge of a particular technique.This book is among the most important medical imaging techniques available today. Each of these scanners is capable of running many different "pulse sequences." These sequences are governed by physics and engineering principles and implemented by software programs that control the MRI hardware.

  • Quantitative Biology

    Mathematical Modeling and Computation
    • 1st Edition
    • Alonso Ogueda-Oliva + 1 more
    • English
    Quantitative Biology provides quantitative and data-driven approaches for analyzing biological and bio-inspired systems, covering the foundations of mathematical modeling, analysis, and computation. The book presents a practical mix of both theory and computation for a variety of biological applications, with tied-in, engaging project activities, instruction, programming language, and technological tools. Modeling approaches combine mathematical foundations, statistical reasoning, and computational thinking, with applications in compartmental, agent-based, bio image, biological interaction, and neural network modeling, as well as machine learning, parameter identification, and applications across societal challenges.Each chapter includes exposure to models and modeling, a foundational instructional framework, benchmark applications, and numerical simulations with a literate programming guided style that helps readers go beyond replication models and into prediction and data-driven discovery. A companion website also features interactive code to accompany projects across each chapter.

  • Biostatistics for Medical and Biomedical Practitioners

    • 2nd Edition
    • Julien I. E. Hoffman
    • English
    Basic Biostatistics for Medical and Biomedical Practitioners, Second Edition makes it easier to plan experiments, with an emphasis on sample size. It also shows what choices are available when simple tests are unsuitable and offers investigators an overview of how the kinds of complex tests that they won't do on their own work. The second edition presents a new, revised and enhanced version of the chapters, taking into consideration new developments and tools available, discussing topics, such as the basic aspects of statistics, continuous distributions, hypothesis testing, discrete distributions, probability in epidemiology and medical diagnosis, comparing means, regression and correlation. This book is a valuable source for students and researchers looking to expand or refresh their understanding of statistics as it applies to the biomedical and research fields. Based on the author’s 40+ years of teaching statistics to medical fellows and biomedical researchers across a wide range of fields, it is a valuable source for researchers who need to understand more about biostatistics to apply it to their work.

  • New Approaches of Protein Function Prediction from Protein Interaction Networks

    • 1st Edition
    • Jingyu Hou
    • English
    New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks. Functional annotation of proteins is vital to biological and clinical research and other applications due to the important roles proteins play in various biological processes. Although the functions of some proteins have been annotated via biological experiments, there are still many proteins whose functions are yet to be annotated due to the limitations of existing methods and the high cost of experiments. To overcome experimental limitations, this book helps users understand the computational approaches that have been rapidly developed for protein function prediction.

  • Mathematical Models for Neglected Tropical Diseases: Essential Tools for Control and Elimination, Part B

    • 1st Edition
    • Volume 94
    • English
    Mathematic Modelling: Improving the Implementation, Monitoring and Evaluation of Interventions, Part B, the latest volume in the Advances in Parasitology series contains comprehensive and up-to-date reviews in the field of mathematic modeling and its implementation within parasitology. The series includes medical studies of parasites of major influence, such as Plasmodium falciparum and trypanosomes, along with reviews of more traditional areas, such as zoology, taxonomy, and life history, all of which shape current thinking and applications.

  • Biostatistics for Medical and Biomedical Practitioners

    • 1st Edition
    • Julien I. E. Hoffman
    • English
    Biostatistics for Practitioners: An Interpretative Guide for Medicine and Biology deals with several aspects of statistics that are indispensable for researchers and students across the biomedical sciences. The book features a step-by-step approach, focusing on standard statistical tests, as well as discussions of the most common errors. The book is based on the author’s 40+ years of teaching statistics to medical fellows and biomedical researchers across a wide range of fields.

  • Mathematical Models for Neglected Tropical Diseases: Essential Tools for Control and Elimination, Part A

    • 1st Edition
    • Volume 87
    • English
    First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Advances in Parasitology includes medical studies of parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. The 2013 impact factor is 4.36.

  • Mathematical Concepts and Methods in Modern Biology

    Using Modern Discrete Models
    • 1st Edition
    • Raina Robeva + 1 more
    • English
    Mathematical Concepts and Methods in Modern Biology offers a quantitative framework for analyzing, predicting, and modulating the behavior of complex biological systems. The book presents important mathematical concepts, methods and tools in the context of essential questions raised in modern biology.Designed around the principles of project-based learning and problem-solving, the book considers biological topics such as neuronal networks, plant population growth, metabolic pathways, and phylogenetic tree reconstruction. The mathematical modeling tools brought to bear on these topics include Boolean and ordinary differential equations, projection matrices, agent-based modeling and several algebraic approaches. Heavy computation in some of the examples is eased by the use of freely available open-source software.

  • Essential Statistical Methods for Medical Statistics

    • 1st Edition
    • J. Philip Miller
    • English
    Essential Statistical Methods for Medical Statistics presents only key contributions which have been selected from the volume in the Handbook of Statistics: Medical Statistics, Volume 27 (2009). While the use of statistics in these fields has a long and rich history, the explosive growth of science in general, and of clinical and epidemiological sciences in particular, has led to the development of new methods and innovative adaptations of standard methods. This volume is appropriately focused for individuals working in these fields. Contributors are internationally renowned experts in their respective areas.

  • Essential Numerical Computer Methods

    • 1st Edition
    • Michael L. Johnson
    • English
    The use of computers and computational methods has become ubiquitous in biological and biomedical research. During the last 2 decades most basic algorithms have not changed, but what has is the huge increase in computer speed and ease of use, along with the corresponding orders of magnitude decrease in cost. A general perception exists that the only applications of computers and computer methods in biological and biomedical research are either basic statistical analysis or the searching of DNA sequence data bases. While these are important applications they only scratch the surface of the current and potential applications of computers and computer methods in biomedical research. The various chapters within this volume include a wide variety of applications that extend far beyond this limited perception. As part of the Reliable Lab Solutions series, Essential Numerical Computer Methods brings together chapters from volumes 210, 240, 321, 383, 384, 454, and 467 of Methods in Enzymology. These chapters provide a general progression from basic numerical methods to more specific biochemical and biomedical applications.

  • Statistical Bioinformatics with R

    • 1st Edition
    • Sunil K. Mathur
    • English
    Statistical Bioinformatics provides a balanced treatment of statistical theory in the context of bioinformatics applications. Designed for a one or two semester senior undergraduate or graduate bioinformatics course, the text takes a broad view of the subject – not just gene expression and sequence analysis, but a careful balance of statistical theory in the context of bioinformatics applications. The inclusion of R & SAS code as well as the development of advanced methodology such as Bayesian and Markov models provides students with the important foundation needed to conduct bioinformatics.

  • Consciousness Transitions

    Phylogenetic, Ontogenetic and Physiological Aspects
    • 1st Edition
    • Hans Liljenström + 1 more
    • English
    It was not long ago when the consciousness was not considered a problem for science. However, this has now changed and the problem of consciousness is considered the greatest challenge to science. In the last decade, a great number of books and articles have been published in the field, but very few have focused on the how consciousness evolves and develops, and what characterizes the transitions between different conscious states, in animals and humans. This book addresses these questions. Renowned researchers from different fields of science (including neurobiology, evolutionary biology, ethology, cognitive science, computational neuroscience and philosophy) contribute with their results and theories in this book, making it a unique collection of the state-of-the-art of this young field of consciousness studies.

  • Laboratory Manual of Biomathematics

    • 1st Edition
    • Raina Robeva + 1 more
    • English
    Laboratory Manual of Biomathematics is a companion to the textbook An Invitation to Biomathematics. This laboratory manual expertly aids students who wish to gain a deeper understanding of solving biological issues with computer programs. It provides hands-on exploration of model development, model validation, and model refinement, enabling students to truly experience advancements made in biology by mathematical models. Each of the projects offered can be used as individual module in traditional biology or mathematics courses such as calculus, ordinary differential equations, elementary probability, statistics, and genetics. Biological topics include: Ecology, Toxicology, Microbiology, Epidemiology, Genetics, Biostatistics, Physiology, Cell Biology, and Molecular Biology . Mathematical topics include Discrete and continuous dynamical systems, difference equations, differential equations, probability distributions, statistics, data transformation, risk function, statistics, approximate entropy, periodic components, and pulse-detection algorithms. It includes more than 120 exercises derived from ongoing research studies. This text is designed for courses in mathematical biology, undergraduate biology majors, as well as general mathematics. The reader is not expected to have any extensive background in either math or biology.

  • Handbook of MRI Pulse Sequences

    • 1st Edition
    • Matt A. Bernstein + 2 more
    • English
    Magnetic Resonance Imaging (MRI) is among the most important medical imaging techniques available today. There is an installed base of approximately 15,000 MRI scanners worldwide. Each of these scanners is capable of running many different "pulse sequences", which are governed by physics and engineering principles, and implemented by software programs that control the MRI hardware. To utilize an MRI scanner to the fullest extent, a conceptual understanding of its pulse sequences is crucial. Handbook of MRI Pulse Sequences offers a complete guide that can help the scientists, engineers, clinicians, and technologists in the field of MRI understand and better employ their scanner.

  • On Growth, Form and Computers

    • 1st Edition
    • Sanjeev Kumar + 1 more
    • English
    Conceived for both computer scientists and biologists alike, this collection of 22 essays highlights the important new role that computers play in developmental biology research. Essays show how through computer modeling, researchers gain further insight into developmental processes. Featured essays also cover their use in designing computer algorithms to tackle computer science problems in areas like neural network design, robot control, evolvable hardware, and more. Peter Bentley, noted for his prolific research on evolutionary computation, and Sanjeev Kumar head up a respected team to guide readers through these very complex and fascinating disciplines.

  • Mathematical Models for Society and Biology

    • 1st Edition
    • Edward Beltrami
    • English
    Mathematical Modeling for Society and Biology engagingly relates mathematics to compelling real-life problems in biology and contemporary society. It shows how mathematical tools can be used to gain insight into these modern, common problems to provide effective, real solutions. Beltrami's creative, non-threatening approach draws on a wealth of interesting examples pertaining to current social and biological issues. Central ideas appear again in different contexts throughout the book, showing the general unity of the modeling process. The models are strikingly novel and based on issues of real concern. Most have never appeared in book form. Through the relevance of these models mathematics becomes not just figures and numbers, but a means to a more refined understanding of the world.

  • Dynamical Models in Biology

    • 1st Edition
    • Miklós Farkas
    • English
    Dynamic Models in Biology offers an introduction to modern mathematical biology. This book provides a short introduction to modern mathematical methods in modeling dynamical phenomena and treats the broad topics of population dynamics, epidemiology, evolution, immunology, morphogenesis, and pattern formation. Primarily employing differential equations, the author presents accessible descriptions of difficult mathematical models. Recent mathematical results are included, but the author's presentation gives intuitive meaning to all the main formulae. Besides mathematicians who want to get acquainted with this relatively new field of applications, this book is useful for physicians, biologists, agricultural engineers, and environmentalists. Key Topics Include: Chaotic dynamics of populations The spread of sexually transmitted diseases Problems of the origin of life Models of immunology Formation of animal hide patterns The intuitive meaning of mathematical formulae explained with many figures Applying new mathematical results in modeling biological phenomena Miklos Farkas is a professor at Budapest University of Technology where he has researched and instructed mathematics for over thirty years. He has taught at universities in the former Soviet Union, Canada, Australia, Venezuela, Nigeria, India, and Columbia. Prof. Farkas received the 1999 Bolyai Award of the Hungarian Academy of Science and the 2001 Albert Szentgyorgyi Award of the Hungarian Ministry of Education.

  • Homology

    The Hierarchical Basis of Comparative Biology
    • 1st Edition
    • Brian K. Hall
    • English
    The application of homology varies depending on the data being examined. This volume represents a state-of-the-art treatment of the different applications of this unifying concept. Chapters deal with homology on all levels, from molecules to behavior, and are authored by leading contributors to systematics, natural history, and evolutionary, developmental, and comparative biology. This paperback reprint of the original hardbound edition continues to commemorate the 150th anniversary of Sir Richard Owen's seminal paper distinguishing homology from analogy.

  • Biomathematics

    Mathematics of Biostructures and Biodynamics
    • 1st Edition
    • S. Andersson + 3 more
    • English
    This book presents new mathematics for the description of structure and dynamics in molecular and cellular biology. On an exponential scale it is possible to combine functions describing inner organisation, including finite periodicity, with functions for outside morphology into a complete definition of structure. This mathematics is particularly fruitful to apply at molecular and atomic distances. The structure descriptions can then be related to atomic and molecular forces and provide information on structural mechanisms. The calculations have been focussed on lipid membranes forming the surface layers of cell organelles. Calculated surfaces represent the mid-surface of the lipid bilayer. Membrane dynamics such as vesicle transport are described in this new language. Periodic membrane assemblies exhibit conformations based on the standing wave oscillations of the bilayer, considered to reflect the true dynamic nature of periodic membrane structures. As an illustration the structure of an endoplasmatic reticulum has been calculated. The transformation of such cell membrane assemblies into cubosomes seems to reflect a transition into vegetative states. The organisation of the lipid bilayer of nerve cells is analyzed, taking into account an earlier observed lipid bilayer phase transition associated with the depolarisation of the membrane. Evidence is given for a new structure of the alveolar surface, relating the mathematical surface defining the bilayer organisation to new experimental data. The surface layer is proposed to consist of a coherent phase, consisting of a lipid-protein bilayer curved according to a classical surface - the CLP surface. Without employing this new mathematics it would not be possible to give an analytical description of this structure and its deformation during the respiration cycle. In more general terms this mathematics is applied to the description of the structure and dynamic properties of motor proteins, cytoskeleton proteins, and RNA/DNA. On a macroscopic scale the motions of cilia, sperm and flagella are modelled. This mathematical description of biological structure and dynamics, biomathematics, also provides significant new information in order to understand the mechanisms governing shape of living organisms.

  • Quantitative Neuroendocrinology

    • 1st Edition
    • Volume 28
    • P. Michael Conn
    • English
    In this volume contemporary methods designed to provide insights into, mathematical structure for, and predictive inferences about neuroendocrine control mechanisms are presented.