Bioactive Components for Functional Foods defines each chemical family of bioactives and collects many of the functional components described in foods and their implications on nutrition and health. It also discusses non-phytochemical components, such as probiotics, bioactive peptides, and fatty acids and their relationship to health. Readers will learn about the metabolism and bioavailability of bioactives, interactions with gut microbiota, interactions of probiotics as food ingredients with other food components, and more.Readers will also find the latest marketing and regulatory issues for functional foods while learning about future trends of micro and nanoencapsulation, delivery systems, and nutraceuticals.
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease, Second Edition examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The new edition of this book is updated with the most recent developments around the therapeutic strategies for drug discovery like amyloid hypothesis, tau, apo E, insulin, and others. It also includes a new chapter on drug delivery to the brain. The content covers diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. Pharmaceutical researchers will benefit from the updated coverage on therapeutic approaches to neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease, Amyotrophic lateral sclerosis, multiple sclerosis, frontotemporal disorder, Huntington’s diseases and many more. Patients and advocacy groups can also benefit from the overview of current treatment options and the scientific progress in the field.
Pain Management in Palliative Care for Patients With Cancer provides healthcare professionals with holistic guidelines and whole-patient treatment philosophies that help practitioners address a patient's total needs. It is the only all-in-one resource for when the cancer patient and palliative care patient are one and the same. While other books focus on analgesics, this resource updates on how early palliative pain treatment can often be achieved by palliative chemotherapy, radiotherapy, or other methods. The myth that palliative care is only appropriate in late-stage illness persists not only among laypersons, but amongst many doctors as well.This book provides insights into what are commonly treated as unrelated disciplines, when in fact cancer care and palliative care have much to teach each other when it comes to oncology patients.
Reconstructive Transplantation and Regenerative Surgery: The New Frontier, Volume Three in the Regenerative and Transplant Medicine series—explores this transformative discipline. This integration aims to overcome the limitations of traditional vascularized organ and tissue transplantation, offering innovative solutions through cutting-edge techniques. As regenerative surgery continues to evolve, this volume serves as a comprehensive resource, highlighting the latest advancements in graft immunomodulation, neuroregeneration, gene editing, diagnostic imaging, ischemia mitigation, and graft preservation. Authored by leading experts, this volume delves into crucial topics such as cell therapies, immunobiologics, neurobiologics, and targeted therapeutic strategies like local immunosuppressive implants and immunocloaking.It also covers cutting-edge diagnostic approaches, including non-invasive molecular imaging, nanotheranostics, and multimodal surveillance techniques. By addressing critical challenges in transplantation and regeneration, this book is an essential reference for surgeons, clinicians, trainees, scientists, and academics dedicated to advancing the field.
Comprehensive Integrative Oncology is a vital resource for clinicians who seek to blend integrative therapies with conventional oncology care to enhance patient outcomes. This book, authored by experts in both conventional and integrative medicine, emphasizes a holistic approach to cancer treatment. It provides practical guidance on incorporating scientifically-backed therapies like botanicals, supplements, mind-body practices, lifestyle changes, nutrition, and exercise into standard cancer care, all while prioritizing patient safety, prevention, and overall wellness. The book delves into the philosophy of integrative oncology, offers tools for practical application, and presents integrative strategies for cancer prevention and symptom management.Additionally, it explores the needs of special populations within oncology. It serves as an indispensable textbook for oncology researchers and practitioners who aim to provide holistic and patient-centered care.
Handbook of Melatonin-Based Therapy and its Applications provides pharmaceutical researchers and health professionals with a comprehensive reference on the applications of melatonin in the therapeutic setting. Succinct, meticulously organized, and expertly written, this book addresses all essential aspects. It starts with an overview of safe use of melatonin, translational aspects, and its prospection. The next section of the book covers a variety of clinical applications, including dosage, pharmacokinetics and pharmacodynamic profiles, toxicity, and principles of action. The chapters in this section cover applications to both adults and pediatric patients suffering from conditions like skin cancers, GI issues, psychiatric, hepatic and ocular conditions.This is a comprehensive resource for pharmaceutical scientists and health professionals involved in developing therapies and applying them to patients. Researchers in the fields of medicine, biology, neuroscience, and pharmacology conducting studies related to melatonin-based will benefit from insights into the latest research findings, clinical trials, and therapeutic approaches.
Fungal and Protozoan Carbonic Anhydrases, Volume 57 in The Enzymes series, explores recent advancements in the study of fungal and protozoan carbonic anhydrases (CAs). This volume presents a comprehensive collection of chapters covering various aspects of these enzymes, including an overview of fungal and protozoan CAs (genetics, molecular biology, and phylogenetics), the structure and function of fungal α-carbonic anhydrases, and an in-depth look at β-carbonic anhydrases in Saccharomyces cerevisiae, Candida spp., and Cryptococcus neoformans. Additional chapters delve into the Malassezia spp. and Sordaria macrospora CAs, as well as protozoan CAs from Plasmodium falciparum, Trypanosoma cruzi, Leishmania spp., Toxoplasma gondii, and Entamoeba histolytica. The volume also addresses the challenges in developing selective fungal and protozoal CA inhibitors as anti-infective agents, providing insights into their potential biomedical applications.
Advances in Agronomy, Volume 194, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.
Feedback Control and Adaptive Learning in Optical-Tweezer Robotics is structured to provide a comprehensive understanding of the integration of robotic feedback control with optical trapping techniques in the field of cell manipulation. It begins by establishing foundational knowledge in dynamic modeling and control theory, laying the groundwork for readers to grasp the intricacies of optical-tweezer robotics. The text then delves into the specifics of optical trapping principles, elucidating the constraints and challenges associated with traditional approaches. It includes the design and implementation of a unified control methodology capable of dynamically adapting to cell movement and escape scenarios. The book emphasizes closed-loop control strategies, enabling readers to navigate the complex interplay between optical forces and robotic manipulation. Additionally, adaptive learning algorithms are explored, offering readers insights into real-time adjustments where the trapping stiffness is unknown. It further addresses open challenges, including overcoming limited field of view, rejecting stochastic disturbances, and efficiently handling the simultaneous trapping and manipulation of multiple cells. Throughout the book, open-access simulations and real-world experiments are integrated to reinforce theoretical concepts. This provides readers with tangible examples and a deeper appreciation for the potential impact of this unified approach in areas such as biomedicine, biotechnology, and microscale robotics.