Fundamentals of Biologicals Regulation: Vaccines and Biotechnology Medicines serves as an introduction to the international regulatory arena in which biologicals are developed and offers an overview of the processes and insight into the scientific concepts underpinning global regulations. In this new edition the book provides more in-depth coverage of Quality by Design, Combination Products, Quality Target Product Profiles, Risk Management Plans and REMS, and switching from reliance on in vivo to in vitro analytical methods. This new edition also reflects the new developments and processes accelerated by the COVID-19 vaccine experience, including emergency use authorizations and conditional marking authorizations. New pedagogic elements and case studies have been added to improve learning outcomes for students. This book provides multiple levels of readership with guidance on basic concepts, a detailed look at regulatory challenges, and practical insight into how regulators consider regulatory science and regulatory process issues across various regions with emphasis on the European Medicines Agency and the U.S. Food and Drug Administration. Graduate students will benefit from the new pedagogic features. Regulatory professionals will have in Fundamentals of Biologicals Regulation: Vaccines and Biotechnology Medicines a complete guide to navigate through the approval process.
Applications in Microwave Processing: Expanding the Scope beyond Cooking, Benefits and Risks provides a comprehensive guide on the principles and recent interest in microwave technology, along with its cross-disciplinary applications. Divided into two sections, the first one discusses the foundation of the principle, emerging applications, and recent interest in microwave technology. The second section explores the cross-discipline applications of microwave technology in different fields, which include bioactive extraction, clinical thermo-therapy, polymer processing, catalytic pyrolysis, thermal sterilization, biopharmaceuticals, wastewater treatment, drying process, mineral processing, and in biological process.Overall, this title discusses the drawback of microwave assisted technology, scalability concerns and outlook. Edited by a team of experts in the field, this book is a great asset for all researchers, Industrial expert, Biotechnologist and all interested in optimal management and usage of microwaves.
Safety and Sustainability Aspects of Food Packaging is a volume of the Sustainable Food Packaging series and serves as a comprehensive guide to the multifaceted world of food packaging. Organized into three sections, this book covers the foundations of food packaging, sustainable food packaging, and legal and regulatory aspects of food packaging. Section 1 provides an overview of the historical background and current trends in food packaging, different types of food packaging materials, and their properties and applications. Section 2 explores innovative solutions for sustainable packaging materials, packaging optimization, logistics, and carbon footprint reduction, edible and biodegradable food packaging, the environmental impact of food packaging, life cycle analysis, and design for recycling and the circular economy. Section 3 delves into regulatory and legal considerations in food packaging, consumer perception, marketing claims, safety considerations, packaging labelling, compliance, and consumer education. With the growing importance of sustainability and increasing regulatory requirements, this series of books represents a comprehensive guide to navigating this rapidly evolving landscape.
Oilseeds and Fats: Trait Improvement, Processing, Properties and Applications covers recent developments in the areas of oilseeds production practices, breeding, and genetic improvement for sustainable production, with an emphasis on processing technologies and nutrition. The book explores eco-friendly extraction methods, waste reduction techniques, and the potential of using waste by-products for energy production or other applications. Specific sections deal with production, breeding, processing methods, composition, and consumption trends, and then delve into oilseeds and fats origin, composition, and characteristics, as well as the principles and methods involved in processing and refining these resources.Additional sections cover oilseed crops processing, properties, and application, offering insights into the utilization of oilseeds and fats to develop new products that meet consumers' evolving preferences, thus addressing environmental concerns. With increasing awareness of environmental issues and climate change, the book underscores the significance of sustainable practices in the oilseed and fats industry.
African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and their Chemoresistance: Part 3. Potential Pharmaceuticals to Overcome Cancers and their Chemoresistance offers detailed information on the best cytotoxic phytoconstituents of African medicinal plants that could be useful for the development of efficient pharmaceuticals that could be further explored to efficiently overcome cancers and their drug resistance. The book identifies and comments on the various classes of cytotoxic African secondary metabolites. The book also clearly identifies and comments on the best cytotoxic molecules identified in African medicinal plants. The book appears an amazing tool for Scientists to have state-of-the-art of the best cytotoxic phytoconstituents from the African flora, and to boost their clinical investigations.
Protein Structure Prediction and Analysis, offers a comprehensive exploration of the methodologies, tools, and techniques utilized in the prediction and analysis of protein structures. This book delves into the fundamental principles of protein folding, modeling, and computational simulations, providing insights into the intricate process of predicting the three-dimensional structures of proteins. From homology modeling to ab initio prediction methods, the text delves into the wide array of predictive algorithms and bioinformatics approaches used to decipher protein structures. Additionally, the book discusses the significance of protein structural analysis in understanding biological functions, drug discovery, and disease mechanisms. With a focus on cutting-edge advancements in the field, this resource serves as a valuable guide for researchers, bioinformaticians, and students seeking to enhance their understanding of protein structure prediction and analysis.
Bioinformatics Essentials: Core Principles and Techniques offers a panoramic view of bioinformatics. The book embarks on a journey that spans genes and genomes, sequence analysis, comparative genomics, functional genomics, and the exciting domain of protein structures and drug design. It describes the basic concepts in bioinformatics, genomic analysis, and ligand based drug design and structure based drug design. Each chapter is imbued with real-world context, demonstrating the practical implications of bioinformatics. Case studies, examples, and hands-on guides bridge the gap between theory and application, enabling readers to translate knowledge into tangible results.Discussions on emerging trends, cutting-edge tools, and potential directions in the field of bioinformatics equip readers to stay at the forefront of advancements. Insights from both biology and computational science converge to provide a well-rounded perspective on the complex biological systems. While designed as a comprehensive guide for learners, this book also serves as a valuable reference for professionals seeking to deepen their understanding, refine their skills, and explore new avenues within bioinformatics.
Sports Physician Handbook, the fourth edition of Team Physician Manual: International Federation of Sports Medicine (FIMS), covers all key area of activity and intervention, from the preparticipation examination to rehabilitation, drug testing, young athlete, female athlete and even environmental issues. The book also surveys the most significant classifications of sports injury, offering clear advice on fieldside assessment, diagnosis and treatment, as well as examining best practice in general aspects of sports medicine, such as prevention and the psychology of injury. Sports Physician Handbook continues the high caliber of authorship from a team of world-leading physicians and scientists from around the world. In short, the fourth edition represents a ‘must have’ reference for any doctor, scientists, physical therapist, or medical professional working in sport.
Emerging Paradigms in Delivery of Therapeutic Agents for the Treatment of Glioblastoma describes the intense research and clinical developments that are required to optimize the available treatment options and the potential side effects to heal brain cancer. The success of this strategy includes the use of validated biomarkers, appropriate patient selection criteria, strategies to prevent adverse events, and the implementation of immunotherapy in multimodal treatment approach. In 18 chapters, this title sets forth the rationales for promising therapies like immunotherapy, including immune checkpoint blockade, chimeric antigen receptor T (CAR T) cell therapy, oncolytic virotherapy, and vaccine therapy.In addition, the book reviews potential novel agents, the current status of preclinical and clinical trials, and the challenges and future perspectives in glioblastoma immuno-oncology. This book is a valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.
As the completely updated comprehensive reference for the eye, its support structures, diseases, and therapies, Encyclopedia of the Eye, Second Edition, Four Volume Set is an important resource for all visual scientists, ophthalmologists, and optometrists, as well as researchers in immunology, infectious disease, cell biology, neurobiology, and related disciplines. This four-volume reference is unique in its coverage of information on all tissues important for vision, including the retina, cornea, and lens. It also covers the physiological and pathophysiologic processes that affect all eye tissues.This Encyclopedia is invaluable for undergraduate students, graduate students, postdoctoral fellows, medical students, and residents who are seeking an introduction to an area of eye research. Each chapter addresses one specific structure or process, reviews the basic concepts, cross-references other chapters within the Encyclopedia and provides citations of relevant primary publications. The Encyclopedia is also particularly useful for visual scientists and practitioners who are investigating a new area, seeking deeper understanding of important research articles in fields adjacent to their own, and/or reviewing a grant or manuscript outside their immediate area of expertise.