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Books in Life sciences

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8771-8780 of 14737 results in All results

Open Source Software in Life Science Research

  • 1st Edition
  • October 31, 2012
  • Lee Harland + 1 more
  • English
  • Hardback
    9 7 8 - 1 - 9 0 7 5 6 8 - 9 7 - 8
  • eBook
    9 7 8 - 1 - 9 0 8 8 1 8 - 2 4 - 9
The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems.The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an ‘omics’ platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry.

Handbook of Proteolytic Enzymes

  • 3rd Edition
  • October 30, 2012
  • Alan J. Barrett + 2 more
  • English
  • eBook
    9 7 8 - 0 - 1 2 - 3 8 2 2 2 0 - 8
Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more.

Genomic and Personalized Medicine

  • 2nd Edition
  • October 30, 2012
  • Geoffrey S. Ginsburg + 1 more
  • English
  • eBook
    9 7 8 - 0 - 1 2 - 3 8 2 2 2 8 - 4
Genomic and Personalized Medicine, Second Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action. As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based analysis in healthcare, and the potential of genomic medicine in future healthcare. The inclusion of the latest information on diagnostic testing, population screening, disease susceptability, and pharmacogenomics makes this work an ideal companion for the many stakeholders of genomic and personalized medicine. With advancing knowledge of the genome across and outside protein-coding regions of DNA, new comprehension of genomic variation and frequencies across populations, the elucidation of advanced strategic approaches to genomic study, and above all in the elaboration of next-generation sequencing, genomic medicine has begun to achieve the much-vaunted transformative health outcomes of the Human Genome Project, almost a decade after its official completion in April 2003.

Insect Growth Disruptors

  • 1st Edition
  • Volume 43
  • October 26, 2012
  • Tarlochan S. Dhadialla
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 9 1 5 0 0 - 9
  • eBook
    9 7 8 - 0 - 1 2 - 3 9 4 4 1 2 - 2
This latest volume in this series contains articles on Arachnid Physiology and Behaviour.The papers in this special issue give rise to key themes for the future.

Biocompatibility and Performance of Medical Devices

  • 1st Edition
  • October 26, 2012
  • Jean-Pierre Boutrand
  • English
  • Hardback
    9 7 8 - 0 - 8 5 7 0 9 - 0 7 0 - 6
  • eBook
    9 7 8 - 0 - 8 5 7 0 9 - 6 4 5 - 6
Implant and device manufacturers are increasingly facing the challenge of proving that their products are safe and biocompatible, and that they will perform as expected. Biocompatibility and performance of medical devices provides an essential guide to the performance analysis of these vital devices.Part one introduces the key concepts and challenges faced in relation to biocompatibility in medical devices, with consideration of biological safety evaluation planning and biomechanical and biochemical compatibility in innovative biomaterials. Part two goes on to discuss the evaluation and characterisation of biocompatibility in medical devices. Topics covered include material and chemical characterisation, allowable limits for toxic leachables, in vivo and in vitro testing and blood compatibility assessment. Testing and interpreting medical device performance is the focus of part three, with chapters describing preclinical performance studies for bone, dental and soft tissue implants, and mechanical testing of soft and hard tissue implants. Part four provides information on the regulation of medical devices in the European Union, Japan and China, and the book concludes with part five, a review of histopathology principles for biocompatibility and performance studies.With its distinguished editor and international team of expert contributors, Biocompatibility and performance of medical devices is a vital tool for all those involved in the research, design, production and application of medical devices, including research directors, production companies and medical regulatory agencies, as well as industry professionals and academics.

Pediatric Endocrinology, An Issue of Endocrinology and Metabolism Clinics

  • 1st Edition
  • Volume 41-4
  • October 26, 2012
  • Robert Rapaport
  • English
  • Hardback
    9 7 8 - 1 - 4 5 5 7 - 4 8 4 1 - 9
  • eBook
    9 7 8 - 1 - 4 5 5 7 - 4 8 4 2 - 6
This issue of Endocrinology and Metabolism Clinics provides essential updates across the spectrum of pediatric endocrinology. Topics covered include Prevention of type 1 and type 2 diabetes mellitus; genetics of growth; diagnosis in prepubescent girls; Turner and Noonan Syndromes; thyroid function in Down Syndrome; chronic disease; effects of ADHD treatment on growth; Vitamin D and bone health; use of statins; and obesity prevention.

Sleep Disorders, An Issue of Neurologic Clinics

  • 1st Edition
  • Volume 30-4
  • October 26, 2012
  • Bradley Vaughn
  • English
  • Hardback
    9 7 8 - 1 - 4 5 5 7 - 4 9 5 1 - 5
  • eBook
    9 7 8 - 1 - 4 5 5 7 - 4 7 7 5 - 7
Sleep disorders are a widely recognized consequence of many neurological pathologies. This issue of Neurologic Clinics features the following articles: Sleep Physiology; Sleep Assessment Tools for the Neurologist; Fitting Sleep into Neurological Practice;  Insomnia; Parasomnias and look-alikes; Sleep Apnea: Obstructive and central; Restless Legs syndrome; Circadian Rhythm; Pediatric Sleep Disorders; Dementia;  Stroke; Epilepsy; CNS Immunological and Infectious; Movement Disorders; Neuromuscular ; Headache; Traumatic Brain Injury; and  Psychiatry in Sleep.

Biomaterials Science

  • 3rd Edition
  • October 25, 2012
  • Buddy D. Ratner + 3 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 8 7 7 8 0 - 8
The revised edition of this renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.

The Neuroscience of Autism Spectrum Disorders

  • 1st Edition
  • October 25, 2012
  • Joseph D. Buxbaum + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 9 1 9 2 4 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 3 9 1 9 3 0 - 4
Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder.  New research is leading to greater understanding of and ability to treat the disorder at an earlier age.  It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years.  With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models.  Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage.  Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise.

Bioactive Food as Dietary Interventions for Cardiovascular Disease

  • 1st Edition
  • October 22, 2012
  • Ronald Ross Watson + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 9 6 4 8 5 - 4
  • eBook
    9 7 8 - 0 - 1 2 - 3 9 6 5 4 0 - 0
One major example of the synergy of bioactive foods and extracts is their role as an antioxidant and the related remediation of cardiovascular disease. There is compelling evidence to suggest that oxidative stress is implicated in the physiology of several major cardiovascular diseases including heart failure and increased free radical formation and reduced antioxidant defences. Studies indicate bioactive foods reduce the incidence of these conditions, suggestive of a potential cardioprotective role of antioxidant nutrients. Bioactive Food as Dietary Interventions for Cardiovascular Disease investigates the role of foods, herbs and novel extracts in moderating the pathology leading to cardiovascular disease. It reviews existing literature, and presents new hypotheses and conclusions on the effects of different bioactive components of the diet.

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