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Bioactive Food as Dietary Interventions for Cardiovascular Disease
Bioactive Foods in Chronic Disease States
- 1st Edition - October 22, 2012
- Editors: Ronald Ross Watson, Victor R Preedy
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 3 9 6 4 8 5 - 4
- eBook ISBN:9 7 8 - 0 - 1 2 - 3 9 6 5 4 0 - 0
One major example of the synergy of bioactive foods and extracts is their role as an antioxidant and the related remediation of cardiovascular disease. There is compelling ev… Read more
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Request a sales quoteOne major example of the synergy of bioactive foods and extracts is their role as an antioxidant and the related remediation of cardiovascular disease. There is compelling evidence to suggest that oxidative stress is implicated in the physiology of several major cardiovascular diseases including heart failure and increased free radical formation and reduced antioxidant defences. Studies indicate bioactive foods reduce the incidence of these conditions, suggestive of a potential cardioprotective role of antioxidant nutrients.
Bioactive Food as Dietary Interventions for Cardiovascular Disease investigates the role of foods, herbs and novel extracts in moderating the pathology leading to cardiovascular disease. It reviews existing literature, and presents new hypotheses and conclusions on the effects of different bioactive components of the diet.
- Addresses the most positive results from dietary interventions using bioactive foods to impact cardiovascular disease
- Documents foods that can affect metabolic syndrome and other related conditions
- Convenient, efficient and effective source that allows readers to identify potential uses of compounds – or indicate those compounds whose use may be of little or no health benefit
- Associated information can be used to understand other diseases that share common etiological pathways
Nutritionists, dieticians, and biomedical researchers whose focus is on identifying cardiovascular and related diseases; food scientists targeting health-related product development.
Acknowledgments for Bioactive Foods in Chronic Disease States
Preface: Bioactive Food for Cardiovascular Disease
Contributors
Chapter 1. Omega-3 Fatty Acids in Prevention of Cardiovascular Disease in Humans: Intervention Trials, Healthy Heart Concept, Future Developments
1 Introduction
2 Role of Omega-3 Fatty Acids in CVD
3 Modern View of Omega Fatty Acid Therapy in CVD
4 Healthy Heart Concept: Less-Known Facts on Omega Fatty Acids
5 Guidelines on Omega Fatty Acid in CVD to Physicians, Nurses: Healthy Heart Concept
6 Implications and Futuristic Prospective
7 Conclusions
Acknowledgments
References
Chapter 2. Herbal Supplements or Herbs in Heart Disease: History, Herbal Foods, Coronary Heart Disease
1 Introduction
2 Relation to TG Metabolism
3 Herbal Foods: Approved Herbs in Cardiovascular Disease
4 Repertory of Herbs and Their Properties
5 Herbs in Human Use
6 Cardioprotective Herb Active Components in Human Use Approved by CDC and Regulated by FDA
7 Conclusion
Acknowledgments
References
Chapter 3. Plant Statins and Heart Failure
1 Heart Failure
2 Statins in the Treatment of HF
3 Complementary Medicine in Heart Failure
4 Plant Sterols/Stanols (Phytosterols)
5 Conclusion
References
Chapter 4. Bioactive Nutrients and Cardiovascular Disease
1 Bioactive Nutrients
References
Chapter 5. Vitamins and Myocardial Infarction in Diabetics
Abbreviations
1 Introduction
2 Patients with Myocardial Infarction and DM Are at Particular Risk
3 Importance of OS in Myocardial Infarction
4 Importance of OS in DM
5 Antioxidant Effect of Vitamins
6 Summary
References
Chapter 6. Cardioprotective Nutrients
1 Introduction
2 Cardioprotective Nutrients
3 Conclusion
References
Relevant Websites
Chapter 7. Fruit and Vegetable Consumption and Risk of Noncommunicable Diseases
Abbreviations
1 Introduction
2 FV and CVD
3 FV and Diabetes Mellitus
4 FV and MetS
5 FV and Hypertension
6 FV and Obesity
7 FV and Bone Mineral Status
8 FV and Cancer
9 Prevention of Noncommunicable Disease by FV Intake
10 Conclusion
References
Relevant Websites
Chapter 8. Diet and Homocysteinemia: A Role in Cardiovascular Disease?
Abbreviations
1 Introduction
2 Homocysteine
3 Homocysteinemia
4 Future Perspectives
References
Chapter 9. Phytosterols and Cardiovascular Disease
Abbreviations
1 Introduction
2 Phytosterols in the Diet
3 Plasma Phytosterols and CVD
4 Phytosterol Mechanism of Action
5 Physical Factors Affecting Phytosterol LDL Lowering
6 Biological Factors Affecting Response to Phytosterols
7 Phytosterols and Pharmaceutical Cholesterol Lowering Therapies
8 Phytosterols, MetS, and Diabetes
9 Phytosterols and Triglyceride Lowering
10 Phytosterols and CVD Risk Reduction
11 Conclusion
12 Summary Points
Glossary
References
Chapter 10. Taurine Effects on Arterial Pressure Control
Abbreviations
1 An Overview of Arterial Pressure Control
2 Physiology of Taurine
3 Taurine and Perinatal Development
4 Taurine and the Heart
5 Taurine and the Autonomic Nervous System
6 Perinatal Taurine and Arterial Pressure Control
7 Adult Taurine Exposure and Hypertension
8 Taurine and the Kidney
9 Summary
References
Chapter 11. Fish Consumption and Risk of Cardiovascular Disease – Part 1
Abbreviations
1 Introduction
2 All-Cause Mortality
3 Coronary Heart Disease Mortality
4 Coronary Heart Disease Prevention
References
Relevant Websites
Chapter 12. Fish Consumption and Risk of Cardiovascular Disease – Part 2
Abbreviations
1 Heart Failure – Left Ventricular Systolic Dysfunction
2 Stroke Prevention
3 Pathophysiological Mechanisms
4 Methodological Problems
5 Fish Contaminants
6 Dietary Guidelines
7 Conclusion
References
Relevant Websites
Chapter 13. Quercetin and Its Metabolites in Heart Health
1 Quercetin: Chemistry and Bioavailability
2 Cardiovascular Disease and Quercetin
3 Safety of Quercetin
Glossary
References
Further Reading
Chapter 14. Vitamin K, Coronary Calcification and Risk of Cardiovascular Disease
1 Vitamin K
2 Vitamin K and Arterial Calcification
3 Vitamin K Intake and Risk of Coronary Heart Disease
4 Vitamin K Intake and Risk of Stroke
5 Conclusion
References
Chapter 15. A Review of the Antioxidant Actions of Three Herbal Medicines (Crataegus monogyna, Ginkgo biloba, and Aesculus hippocastanum) on the Treatment of Cardiovascular Diseases
1 Introduction
2 Hawthorn
3 Ginkgo
4 Horse Chestnut Seed
5 Concluding Statements
6 Summary
Glossary
References
Further Reading
Relevant Websites
Chapter 16. Grape Polyphenols in Heart Health Promotion
1 Introduction
2 Grape Chemistry and Bioavailability
3 Human Studies – Cardiovascular Effects
4 Potential Mechanisms of Effect
5 Translational Frontiers
References
Chapter 17. Cacao for the Prevention of Cardiovascular Diseases
Abbreviations
1 Introduction
2 Dietary Antioxidants
3 The Role of Tryptophan Metabolism and Neopterin Formation in Cardiovascular Disease
4 Cacao to Enhance Mood
5 Conclusion
References
Chapter 18. Phytoestrogens and the Role in Cardiovascular Health: To Consume or Not to Consume?
Abbreviations
1 Background and Significance
2 Phytoestrogens and Biology, Chemistry, and Pharmacokinetics
3 Biological Modes of Action: Estrogenic, Antiestrogenic, and ER Independent Modes of Action
4 Phytoestrogens and Cardiovascular Health
5 Confounding Factors to Consider
6 Summary and Concluding Remarks
Acknowledgments
References
Chapter 19. Probiotic Species on Cardiovascular Disease: The Use of Probiotics to Reduce Cardiovascular Disease Risk Factors
Abbreviations
1 Introduction
2 Hypocholesterolemic Effect of Probiotics
3 Mechanism of Hypocholesterolemic Effect of Probiotics
4 Hypotensive Effect of Fermented Milk Product
5 Mechanisms of Blood Pressure Lowering
6 Alternative Targets of Bioactive Peptides
7 Effects of Peptides Other Than Blood Pressure-lowering Effect
8 Lipopolysaccharide (LPS), Inflammation, CVD, and Probiotics
9 Improving Insulin Resistance Associated with Inflammation
10 Conclusions and Future Directions
Acknowledgments
References
Chapter 20. Dairy Foods and Cardiovascular Diseases
Abbreviations
1 Prevalence of Cardiovascular Diseases in the United States
2 Mechanism of Inflammation
3 Role of Selected Foods in the Prevention of Inflammation in CVD
4 Summary
References
Chapter 21. Red Palm Oil Carotenoids: Potential Role in Disease Prevention
Abbreviations
1 Background
2 Carotenoid Content of RPO
3 Biological Significance of Dietary Carotenoids
4 Carotenoids in Health and Disease
5 Safety of Carotenoids from Natural Food Sources
6 Nutritional Value of RPO
References
Further Reading
Chapter 22. Bioactive Compounds in Red Palm Oil Can Modulate Mechanisms of Actions in In Vitro Anoxic Perfused Rat Hearts
1 Introduction
2 Involvement of the Prosurvival and Apoptotic Pathways in Red Palm Oil Protection
3 Involvement of the NO-CGMP Pathway and MMP in Red Palm Oil Protection
4 Optimal Feeding Period and Dosage of Red Palm Oil to Offer Protection Against Anoxia
5 Red Palm Oil Protection in Other Disease Models
6 Summary
References
Chapter 23. The Effect of L-Carnitine Supplement and Its Derivatives on Cardiovascular Disease
Abbreviations
1 Introduction
2 The Effect of LC and its Derivates on the Cardiovascular Risk Factors
3 The Effect of LC and its Derivatives on Patients with Atherosclerosis
4 The Effect of LC and its Derivatives on Patients with Congestive Heart Failure/Cardiomyopathy
References
Chapter 24. Dietary Blueberry Supplementation as a Means of Lowering High Blood Pressure
Abbreviations
1 Hypertension
2 Conventional Treatment of Hypertension
3 Treatment of Hypertension Through Functional Foods and Phytochemicals
4 Conclusion
Glossary
References
Further Reading
Relevant Websites
Chapter 25. Vitamin D and Cardiometabolic Risks
Abbreviations
1 Introduction
2 The Metabolic Syndrome
3 IR, Diabetes, and Vitamin D
4 Overweight, Obesity, and Vitamin D
5 Lipoproteins and Vitamin D
6 Hypertension
7 CVD and Vitamin D
8 Final Remarks
Glossary
References
Further Reading
Chapter 26. Phytosterols and Micronutrients for Heart Health
Abbreviations
1 Introduction
2 Micronutrients
3 Phytosterols
4 Conclusion
References
Chapter 27. Protection by Plant Flavonoids Against Myocardial Ischemia–Reperfusion Injury
Abbreviations
1 Introduction
2 Flavonols
3 Flavanols
4 Proanthocyanidins
5 Flavanones
6 Flavones
7 Isoflavones
8 Anthocyanins
9 Conclusions
References
Chapter 28. Bioactive Compounds in Heart Disease
1 Introduction
2 Flavonoids
3 Phytoestrogens
4 Resveratrol
5 Carotenoids
6 Organosulfur Compounds
7 Polyunsaturated Fatty Acids
8 Conclusion
Relevant Website
References
Chapter 29. A Critical Appraisal of the Individual Constituents of Indian Diet in Modulating Cardiovascular Risk
1 Introduction
2 The Indian Diet and Cuisine
3 Cereals
4 Pulses
5 Nuts
6 Dry Fruits
7 Spices
8 Fruits and Vegetables
9 Oils and Fats
10 Fish and Fish Oils
11 Milk and Dairy Products
12 Sweets and Desserts
13 Meat and Meat Products
14 Egg and Egg Products
15 Consideration of High Salt Intake in India
16 Micronutrients and Cardiac Health
17 Conclusions
Acknowledgments
References
Chapter 30. Omega-3 Fatty Acids in Prevention of Cardiovascular Disease in Humans: Chemistry, Dyslipidemia
1 Introduction
2 Omega Fatty Acids and Dyslipidemia
3 Mechanism of Lipid Lowering and Cardioprotection by Omega-3 Fatty Acid Intake
4 Conclusion
Acknowledgments
References
Chapter 31. Herbal Supplements or Herbs in Heart Disease: Herbiceutical Formulation, Clinical Trials, Futuristic Developments
1 Introduction
2 Herbiceutical Formula in Heart Disease Treatment
3 Herbiceutical Testing
4 Cardioprotective Herbal Active Components in Human Use Approved by CDC and Regulated by FDA
5 Pharmaceutical Approach of Herbiceutical Formula with Antiarrhythmic Properties
6 Treatment Recommendations for Herbiceuticals in Cardiovascular Prevention
7 Conclusion
Acknowledgments
References
Chapter 32. Fish Proteins in Coronary Artery Disease Prevention: Amino Acid–Fatty Acid Concept
1 Introduction
2 Fish Proteins and Amino Acids
3 Fish Proteins in Cardiac Prevention
4 Effect of Fish Dietary Proteins on Coronary Artery Disease
5 Effect of Fish Proteins on Atherosclerosis
6 Prevention of CAD: Fish Diet
7 Conclusion
Appendix 1 New method developed: SDS-PAGE electrophoresis
References
Chapter 33. Herbs Used in Traditional Chinese Medicine in Treatment of Heart Diseases
Abbreviations
1 Introduction
2 TCM Herbs
3 Discussion
References
Chapter 34. Protective Effect of Garlic (Allium sativum L.) Against Atherosclerosis
Abbreviations
1 Introduction
2 Etiopathogenesis of Atherosclerosis
3 Prevention of Atherosclerosis
4 Plants in the Prevention of Atherosclerosis
5 Allium sativum
6 Bioactive Compounds in Garlic
7 Protective Effect of Garlic Against Atherosclerosis
8 Conclusions
Acknowledgment
References
Chapter 35. Potential of Soy Phytochemicals in Cardiomyocyte Regeneration and Risk Reduction of Coronary Heart Disease
Abbreviations
1 Introduction and Overview
2 Pathogenesis of CHD
3 Cardiomyocyte Regeneration
4 Soy Phytochemicals and Cardioprotection
5 Role of soy Isoflavones in Control of Cardiomyocyte Proliferation, Cell Cycle Reentry, and Regeneration
6 Conclusion and Future Studies
Acknowledgments
References
Chapter 36. Fish Oil Fatty Acids and Vascular Reactivity
Abbreviations
1 Introduction
2 Observational Studies Examining the Relationship Between Habitual LC n-3 PUFA Intake with Carotid IMT and Vascular Reactivity
3 Chronic Studies Examining the Impact of LC n-3 PUFA Supplementation on Vascular Function
4 Acute Studies Examining the Effects of LC n-3 PUFA on Postprandial Vascular Reactivity
5 Potential Mechanisms
6 Conclusions
References
Relevant Website
Chapter 37. Counteracting the Inflammatory Response in the Atherosclerosis Bioactive Products
1 Introduction
2 Inflammatory Mechanisms in Atherosclerosis
3 Low-Density Lipoprotein
4 Oxidative Stress and Vascular Function
5 Antioxidants – Protective Role in CVD
6 Concluding Remarks
References
Chapter 38. Cardioprotective Efficacy of Alternative and Complementary Therapeutics
1 Introduction
2 Acorus calamus
3 Aegle marmelos
4 Allium cepa
5 Allium sativum
6 Centella asiatica
7 Commiphora wightii
8 Emblica officinalis
9 Ocimum sanctum
10 Picrorhiza kurroa
11 Terminalia arjun
12 Terminalia chebula
13 Tinospora cordifolia
14 Withania somnifera
15 Zingiber officinale
16 Conclusions
Acknowledgments
References
Chapter 39. Effect of Terminalia arjuna on Cardiac Hypertrophy
Abbreviations
1 Terminalia arjuna: A Cardioprotective Plant
2 Terminalia arjuna and Cardiac Hypertrophy
3 Conclusion and Future Perspective
References
Chapter 40. Plant Sterols and Artery Disease
Abbreviations
1 What Are Plant Sterols?
2 Metabolism of Phytosterols in Humans
3 Plant Sterols and Artery Disease in Humans
4 Conclusions
References
Chapter 41. Antiatherogenic Effects of Ginger (Zingiber officinale Roscoe): Scientific Observations and Ethnomedicinal Validation
Abbreviations
1 Introduction
2 Etiopathogenesis of Atherosclerosis
3 Plants in the Prevention of Atherosclerosis
4 Protective Effects of Ginger Against Atherosclerosis
5 Conclusion
Acknowledgment
References
Index
- No. of pages: 746
- Language: English
- Edition: 1
- Published: October 22, 2012
- Imprint: Academic Press
- Hardback ISBN: 9780123964854
- eBook ISBN: 9780123965400
RW
Ronald Ross Watson
Ronald Ross Watson, PhD, is Professor of Health Promotion Sciences at the University of Arizona, Mel and Enid Zuckerman College of Public Health. Dr. Watson began his research in public health at the Harvard School of Public Health as a Fellow in 1971 doing field work on vaccines in Saudi Arabia. He has done clinical studies in Colombia, Iran, Egypt, Saudi Arabia and the United States which provides a broad international view of public health. He has served in the military reserve hospital for 17 years with extensive training in medical responses to disasters as the chief biochemistry officer of a general hospital, retiring as a Lt. Colonel. He is a distinguished member of several national and international nutrition, immunology, and cancer societies. Dr. Watson’s career has involved studying many lifestyle aspects for their uses in health promotion. He has edited over 100 biomedical reference books and 450 papers and chapters. His teaching and research focuses on alcohol, tobacco, and drugs of abuse in heart function and disease in mouse models.
Affiliations and expertise
Professor, Mel and Enid Zuckerman College of Public Health and School of Medicine, Arizona Health Sciences Center, University of Arizona, Tucson, AZ, USAVP
Victor R Preedy
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.
Affiliations and expertise
Professor, Department of Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK Visiting Professor, University of Hull, UKRead Bioactive Food as Dietary Interventions for Cardiovascular Disease on ScienceDirect