Books in Life sciences

Pharmacoepigenetics

2nd Edition
Volume 10
July 18, 2025
Ramón Cacabelos
English
Hardback
9 7 8 0 4 4 3 1 8 7 2 2 3
eBook
9 7 8 0 4 4 3 1 8 7 2 3 0

Pharmacoepigenetics, Second Edition, Volume Ten in the Translational Epigenetics series, is a comprehensive reference on the role of epigenetics and epigenomics in drug discovery and development. Here, leading international researchers from across academia, clinical settings, and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine.This new edition has been fully revised to address recent advances in epigenetics, from new natural and synthetic compounds with epigenetic effects to the role of epigenetics in the pathogenesis of a growing number of complex diseases, including further cancers, cardiovascular disorders, and brain disorders. Newly identified molecular components in the functional architecture of the epigenetic machinery, as well as practical and relevant pharmacoepigenetics topics related to COVID-19 and other world health challenges are also discussed.

Essentials of Neuroanesthesia

2nd Edition
July 18, 2025
Hemanshu Prabhakar
English
Hardback
9 7 8 0 4 4 3 2 2 2 7 3 3
eBook
9 7 8 0 4 4 3 2 2 2 7 2 6

Essentials of Neuroanesthesia, Second Edition continues to offer valuable insights into the anesthetic management of neurosurgical and neurologic patients, covering all topics related to neuroanesthesia and providing essential knowledge on the brain and spinal cord. The book includes chapters on anatomy, physiology, and pharmacology, along with specific chapters addressing various neurosurgical and neurological problems and their anesthetic management. This updated edition introduces new chapters on artificial intelligence in neurosciences, the role of simulation in clinical neurosciences, robotic neurosurgery, trigeminal neuralgia, coexisting transplanted organs, brain resuscitation after cardiac arrest, and more.In addition to the foundational knowledge, the book addresses related issues such as the evidence-based practice of neuroanesthesia, sterilization techniques, biostatistics, and ethical issues. It is a valuable resource for trainees, clinicians, and researchers in the fields of neuroanesthesia, neurocritical care, critical care, neurosurgery, and neurology. The comprehensive coverage and updated content make it an indispensable guide for understanding and managing the complexities of neuroanesthesia.

Sorghum and Millets

3rd Edition
July 18, 2025
John Taylor + 2 more
English
Paperback
9 7 8 0 4 4 3 2 3 9 5 4 0
eBook
9 7 8 0 4 4 3 2 3 9 5 5 7

Sorghum and Millets: Chemistry, Technology, and Nutritional Attributes, Third Edition is the leading resource for state-of-art knowledge on grain science and utilization surrounding sorghum and millets. The book covers important scientific knowledge, including basic science—genetics, chemistry, and biochemistry—food chemistry, nutritional quality and health-promoting attributes, agronomy, and food and feed processing technologies. Other sections delve into structure, chemistry, biochemistry, grain components, and the technologies used for food processing. Additionally, it provides holistic and complete information about all technologies in the sorghum and millets food value chain, from genomics-based breeding to grain- and product quality assurance.Sorghum and the millets are the 5th and 6th most important cereal grains in terms of production and are cultivated across the world. They have a very wide range of end-uses as traditional staple foods and beverages, modern processed foods, and with respect to sorghum, industrial applications, including biofuels, and as an animal and aquaculture feedstuff.

Immuno-oncology and Immunotherapy Part D

1st Edition
Volume 196
July 18, 2025
Lorenzo Galluzzi + 2 more
English
Hardback
9 7 8 0 4 4 3 2 9 6 1 8 5
eBook
9 7 8 0 4 4 3 2 9 6 1 9 2

Immuno-oncology and immunotherapy, Part D, Volume 196 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Investigating the endothelial-immune axis in cancer, Establishing Tyro3, Axl, and Mertk Chinese Hamster Ovary (CHO) Reporter Cell Lines for Cancer Immunology and Therapeutic Applications, Amino acid analog-based labelling of the immunomodulatory cancer secretome, Human and mouse iNKT cell expansion and engineering with viral vectors, Next-generation deconvolution of the tumor microenvironment with omnideconv, and much more.Additional sections cover Comprehensive prediction of tumor neoantigens with NextNEOpi, Ex vivo profiling of organotypic tumor spheroids in 3D microfluidic culture, A flow cytometry-based assay for evaluation of T cell activation and degranulation in coculture systems, An adenosine production assay suitable for 2D and 3D cancer cell culture, Determination of lactate in the tumor interstitial fluid, Combined in vitro differentiation and cell sorting-based isolation of highly pure mouse bone marrow-derived basophils, Organ-on-Chip immunostaining method for three-dimensional identification and study of immune cells responding to drug-treated tumor cells, and much more.

Regulated Cell Death in Neurodegenerative Disorders

1st Edition
July 18, 2025
Heba Mohamed Mansour + 1 more
English
Paperback
9 7 8 0 4 4 3 3 2 8 5 2 7
eBook
9 7 8 0 4 4 3 3 2 8 5 3 4

Regulated Cell Death in Neurodegenerative Disorders is a comprehensive exploration of the mechanisms and implications of RCD within the realm of neurodegenerative diseases. The book delves into various forms of RCD such as apoptosis, necroptosis, ferroptosis, pyroptosis, and autophagy-mediated cell death, shedding light on their specific roles in disorders like Alzheimer’s, Parkinson’s, Multiple sclerosis, Amyotrophic lateral sclerosis, and Huntington’s. Written by leading experts, each chapter offers unique insights into cellular demise, providing valuable information on treatment options and therapeutic targets. The book features 14 chapters that cover molecular, cellular, and pharmacological mechanisms from an applied science perspective.Topics include the importance of chaperones, kinases, growth factors, inflammaging, mitochondrial dynamics, and oxidative stress. It presents targeted strategies to prevent cell death, reflecting ongoing pursuits in understanding and innovating treatments for neurodegenerative diseases. By offering therapeutic strategies to modulate RCD, this book not only shares knowledge but also provides hope for future advancements in combating these debilitating conditions.

Fruit Microbiome

1st Edition
July 18, 2025
Ajay Kumar + 3 more
English
Paperback
9 7 8 0 4 4 3 3 3 9 6 3 9
eBook
9 7 8 0 4 4 3 3 3 9 6 4 6

Fruit Microbiome: Emerging Aspects in Postharvest Disease Management covers all areas of microbial ecology and serves as a basis for innovative methods of microbiome engineering and the incorporation of probiotics on fruit nutritional quality. Emphasizing the latest advancements in the fruit microbiome and applications in biocontrol perspectives, the book includes advanced and recent insights into the development of microbial pesticides that will be helpful for those seeking ways to protect and improve plant health and yield protection.Phyto-mic... plays a crucial role in maintaining the health and productivity of all plants, including fruit plants whose yield contributes to global food security. Fruit also harbors numerous microbial communities as an epiphytes or endophytes, and theses microbes play a vital role in protecting them from pathogen invasion during pre-or- postharvest storage. Further, the development and commercialization of several biocontrol products derived from fruits microbiome have proven relevant in broader plant disease management.

Recent Advances in Liver Cirrhosis Related Complications

1st Edition
July 15, 2025
Xingshun Qi + 1 more
English
Paperback
9 7 8 0 4 4 3 2 1 9 3 8 2
eBook
9 7 8 0 4 4 3 2 1 9 3 7 5

Recent Advances in Liver Cirrhosis Related Complications provides comprehensive coverage on the contemporary management of liver cirrhosis related complications and future directions for the field. Content covers epidemiology, diagnosis, risk stratification, and pathophysiology. Contents include coverage of the gut microbiota, ascites, and gastrointestinal bleeding as well as the challenges of hepatic encephalopathy, acute kidney injury, bacterial infections, coagulation abnormality, and venous thromboembolism, amongst others. This is the perfect resource for practicing gastroenterologists and hepatologists as well as family physicians and investigators who are skilled at the management of liver cirrhosis and its complications.

Narcolepsy

1st Edition
July 15, 2025
Ahmed S. BaHammam + 2 more
English
Paperback
9 7 8 0 4 4 3 3 0 0 0 4 2
eBook
9 7 8 0 4 4 3 3 0 0 0 5 9

Narcolepsy: Integrating Basic and Clinical Knowledge provides comprehensive coverage of narcolepsy-related topics. The book offers updated, deep coverage of its diagnosis, treatment, and impact on mental health based on the latest research findings and clinical practices. Its interdisciplinary approach brings together experts from different specialties, such as sleep medicine, psychology, and neurology to offer a more holistic understanding. This allows for a more nuanced discussion of how narcolepsy interacts with various aspects of health and well-being. Researchers and clinicians will find within this book novel information on pathophysiology and neurobiology, as well as behavioral and psychosocial considerations.Users will find this to be a resource that takes a deep dive into narcolepsy, introducing topics never before discussed in books on the topic, including COVID-19 and sleep, as well as immunotherapy and gene therapy. It’s the cutting-edge medical volume professionals need, whether narcolepsy specialists or more casual readers.

Neurotoxicity of Solvents

1st Edition
Volume 14
July 15, 2025
Christoph van Thriel
English
Hardback
9 7 8 0 4 4 3 3 4 3 2 8 5
eBook
9 7 8 0 4 4 3 3 4 3 2 9 2

Neurotoxicity of Solvents, Volume Fourteen highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including the Effect of toluene on memory: A focus on humans, experimental models and treatment approaches, Neurotoxicological Mechanisms of Ethanol, Neurobehavioral Aspects and Methodology of Solvents, Organic solvents and neurodegenerative diseases: exploring a possible link, Neurotoxicity of propylene ethers, An ecotoxicological view on solvents neurotoxicity, and The olfactory system as a target of solvent toxicity.

Enfermedad vascular cerebral en jóvenes

1st Edition
July 15, 2025
Fernando Barinagarrementeria Aldatz + 1 more
Spanish

Enfermedad vascular cerebral en jóvenes constituye una contribución inédita en lengua española sobre un tema tan específico como trascendente: la enfermedad vascular cerebral (EVC) en la población joven, escrita por autores internacionales líderes en los diferentes aspectos de este complejo tema. En las últimas décadas, la EVC en jóvenes ha dejado de ser una rareza clínica para convertirse en un problema creciente, con implicaciones significativas por lo que hace a su diagnóstico y manejo. El adecuado abordaje clínico y tecnológico es indispensable para la solución de esta compleja patología, y este título ofrece las herramientas necesarias para su estudio. La presente obra proporciona una revisión exhaustiva de los diferentes aspectos de la enfermedad, abordando su incidencia y factores de riesgo, tanto clásicos como nuevos. También se revisan las diferentes etiologías, y se proporciona un marco para la toma de decisiones clínicas y el manejo de los trastornos cerebrovasculares tanto frecuentes como infrecuentes en esta población.

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