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Elsevier

Books in Life sciences

  • Phytochemicals and Hallmarks of Cancer

    From Molecules to Medicine
    • 1st Edition
    • Gautam Sethi + 1 more
    • English
    Phytochemicals and Hallmarks of Cancer: From Molecules to Medicine delves into the potential of phytomedicine to effectively address both established and emerging hallmarks of cancer, offering valuable insights into their translational applications from bench to bedside. The book provides comprehensive information about how the plant-derived product tackles cancer by targeting different hall markers that drive cancer progression. In 12 chapters the book not only describes the implications of plant products on cancer immunotherapy, gives insight in the hurdles in clinical translating plant derived products for cancer therapy, but also focuses on the therapeutic aspects of phytochemicals, providing insights into how understanding of mechanism of actions of phytochemicals can aid to develop innovative therapies.By addressing these knowledge and information needs Phytochemicals and Hallmarks of Cancer: From Molecules to Medicine is designed to be accessible to clinicians and researchers alike in the field of phytochemical applications in medicine.

  • Advanced Methodologies to Study and Enhance Cellular Cytotoxicity Against Cancer

    • 1st Edition
    • Volume 207
    • English
    Advanced Methodologies to Study and Enhance Cellular Cytotoxicity Against Cancer, Volume 207 covers the latest techniques and strategies used to investigate and boost cytotoxic activity in cells targeting cancer. Chapters include An ex vivo assay to assess CAR T cell cytotoxicity in viable tumor tissues using a two-step staining protocol, New protocol to measure mitochondria polarization/functio... at the immunological synapse, Analysis of CAR-T cell–mediated cytotoxicity in solid tumor models, Investigation of the in vitro lytic capacity of CAR-T by microscopyal, Antigen-specific T cell cytotoxicity toward target tumor cells, In vitro expansion of stem-like memory T cells via D-mannose supplementation, and much more.Additional chapters explore High-throughput time-lapse imaging of B16 target cell killing by ovalbumin-specific CD8+ T cells, Evaluation of an intracellular magneto-mechanical approach for regulating dendritic cell activation, Analyzing the effect of NK cells on in-vivo models of tumor dissemination by digital pathology and flow cytometry, Super-resolution imaging of the NK cell synapse on supported lipid bilayers using MINFLUX nanoscopy, ASSESSMENT OF NK CELL CYTOTOXICITY INDUCED BY IL-15 BASED IMMUNOTHERAPY AGAINST CANCER CELLS, Combined phenotyping and functional analysis of isolated human natural killer cells using spectral flow cytometry, and much more.

  • Biomechanics and Mechanobiology of Bone

    From Model to Patient
    • 1st Edition
    • Luis Cardoso + 2 more
    • English
    Biomechanics and Mechanobiology of Bone: From Model to Patient provides readers with a comprehensive overview of the modelling and assessment of bone biomechanics. It addresses topics such as biosubstitutes and bone implants from the point of view of design, properties, computational modeling, and choice of biomaterials. It concentrates on the biomechanics and mechanobiology modeling approaches of bone, including biological models, multiphysical approaches, surface and volumetric growth models, and bone fluid flow models. This is augmented by case studies and examples of models for computer-aided diagnosis, treatment, and monitoring of bone diseases. Readers are introduced to bone physiology, adaptation, and disease, including cellular aspects at the root of bone mechanotransduction and leading to bone growth and remodeling, and management of diseases. Chapters also cover the mechanical, multiphysical multiscale properties of bone and constitutive laws including bone viscoelasticity, poroelasticity, bone damage, fatigue and fracture, as well as measurement techniques of bone properties.

  • Multifunctional Nano pharmaceuticals for Biomedical Applications

    • 1st Edition
    • Sushil K. Kashaw + 3 more
    • English
    Multifunctional Nanopharmaceuticals for Biomedical Applications covers the latest advancements in multifunctional nanopharmaceuticals while also addressing the pressing need for innovative solutions for unmet medical challenges. Each chapter explores key topics such as the fundamentals of nanotechnology and drug delivery, PEGylated lipid carriers for cancer theranostics, and the latest in biomimetic nanomicells and nanorobots. With detailed discussions on design strategies, formulation techniques, and regulatory aspects, readers will gain a thorough understanding of the complexities and innovations in this dynamic field. The exploration of clinical applications and future trends also equips readers with the knowledge to navigate the evolving landscape of nanomedicine.This is an essential resource for researchers interested in the transformative potential of nanotechnology in drug delivery and disease treatment. It empowers readers to harness cutting-edge technologies for effective therapies, paving the way for a new era of personalized, precise, and potent medicine. With the rapid evolution of nanomedicine, this book serves as a crucial tool for researchers, students, healthcare professionals, and industry experts alike, bridging the gap between fundamental concepts and their real-world applications.

  • Advances in Agronomy

    • 1st Edition
    • Volume 198
    • English
    Advances in Agronomy, Volume 198, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Combinatorial Biotechnology

    Methods for Synthesis of Peptide, Oligonucleotide and Oligosaccharide Libraries and Applications
    • 1st Edition
    • Preeti Srivastava
    • English
    Combinatorial Biotechnology: Methods for Synthesis of Peptide, Oligonucleotide and Oligosaccharide Libraries and Applications covers methods used for synthesizing peptide, oligonucleotide, and oligosaccharide libraries. It presents the concepts of combinatorial biotechnology, detailing both solid phase and solution phase synthesis techniques, including modern biological methods such as in vitro and in vivo display libraries. Key topics include solid phase synthesis, parallel peptide synthesis, encoding technologies, deconvolution methods, and chemical and biological ligations. With chapters covering the chemical and biological synthesis of recombinant peptides and proteins, as well as the genetic reprogramming of the genetic code, this book offers a rich source of practical guidance.The inclusion of advanced methods and illustrative examples makes it a unique and essential reference in the field. This book is an essential resource for undergraduate and postgraduate students in biochemical engineering, biotechnology, and biosciences, as well as industry professionals in R&D divisions. It equips readers with the latest techniques and applications in combinatorial biotechnology, addressing current challenges and advancing their research and development efforts.

  • Antimicrobial Peptides

    From Science to Applications
    • 1st Edition
    • Anil Kumar Chhillar + 4 more
    • English
    Antimicrobial Peptides: From Science to Applications provides comprehensive coverage on the biology, diversity, and mechanisms of action associated with antimicrobial peptides (AMPs). The book aims to equip readers with the knowledge required to understand, harness, and optimize these molecules for development and application across various sectors. Sections overview the biology and diversity of antimicrobial peptides, cover their molecular structure and function, and delve into their unique mechanisms of action and evolutionary significance in nature. Subsequent chapters go on to explore the utilization of AMPs in medicine, agriculture, the environment, and biotechnology.Culmin... in discussions on future trends, regulatory considerations, and strategies to overcome challenges, this book is an informative reference for researchers, scientists, graduate students, and industry professionals engaged in the study and development of antimicrobial peptides as a potential solution to address pressing challenges such as antibiotic resistance, food security, and environmental sustainability.

  • Microbial and Biochar Technology for Waste Valorization

    • 1st Edition
    • Maulin P. Shah + 2 more
    • English
    Microbial and Biochar Technology for Waste Valorization delves into the innovative integration of microbial and biochar technologies, presenting a compelling case for their combined utilization in waste reuse to aid environmental sustainability. The book opens with a discussion of current and emerging environmental issues and the need for implementing integrated microbe-biochar processes. Initial chapters explore the fundamentals of biochar, its sources, synthesis routes, characterization methods, its impact on soil, environment, and water microbiomes, and approaches to biochar production.The book then delves deeper into its role in environmental remediation, its suitability as a microbe carrier, and the combination of biochar and microbes for various applications, including microbial fuel cells, biofertilizer, biopesticide, and water treatment processes. Final sections highlight the use of machine learning and AI for predicting biochar characteristics, biochar's potential in promoting a circular economy and carbon neutrality, and future directions for biochar-microbe applications.

  • Building Resilient Water and Food Systems under Climate Change

    • 1st Edition
    • Thendiyath Roshni + 3 more
    • English
    Building Resilient Water and Food Systems Under Climate Change aims to help readers understand and implement strategies to build resilient communities that can ensure sustainable access to both food systems and water resources. The book examines the impact of climate change on food and water security and explores how communities can adapt to these challenges. It provides an in-depth analysis of climate change science, focusing on its effects on agriculture, water resources, and ecosystems. Additionally, the book showcases case studies of communities that have successfully employed resilience strategies by integrating traditional and local knowledge systems with modern techniques. Readers will find practical solutions for managing risks and building sustainable, climate-resilient systems. By combining theoretical insights with real-world examples, this comprehensive guide is designed for policymakers, researchers, and community leaders to effectively safeguard essential resources at both macro and micro levels in the face of climate change.

  • AI-enabled Sustainable Healthcare

    Demystifying Secure Quantum Blockchain
    • 1st Edition
    • M. Nivaashini + 4 more
    • English
    AI-Enabled Sustainable Healthcare: Demystifying Secure Quantum Blockchain explores the convergence of quantum computing, blockchain technology, and artificial intelligence in the context of healthcare. In today's rapidly evolving technological landscape, traditional healthcare systems face challenges related to data security, interoperability, and the efficient utilization of patient information. The emergence of quantum computing, blockchain, and AI presents unprecedented opportunities to overcome these challenges and revolutionize healthcare delivery. This book provides a clear and accessible overview of these complex technologies and their potential applications in healthcare. By demystifying these concepts and illustrating their real-world implications, the book equips readers with the knowledge and insights needed to navigate the intersection of technology and healthcare effectively. Furthermore, as the demand for secure, transparent, and sustainable healthcare solutions continues to grow, there is an urgent need for informed discussions and innovative approaches in this field.

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