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Books in Life sciences

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4261-4270 of 14737 results in All results

Medical Innovation

  • 1st Edition
  • May 24, 2018
  • Kevin E. Behrns + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 4 9 2 6 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 4 9 2 7 - 0
Medical Innovation: Concept to Commercialization is a practical, step-by-step approach on how to move a novel concept through development to realize a commercially successful product. Real-world experience cases and knowledgeable contributors provide lessons that cover the practices of diverse organizations and multiple products. This important reference will help improve success and avoid innovation failure for translational researchers, entrepreneurs, medical school educators, biomedical engineering students and faculty, and aspiring physicians.

A Practical Guide to Writing a Ruth L. Kirschstein NRSA Grant

  • 2nd Edition
  • May 24, 2018
  • Andrew D. Hollenbach
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 5 3 3 6 - 9
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 5 3 3 7 - 6
A Practical Guide to Writing a Ruth L. Kirschstein NRSA Grant, Second Edition, continues to provide F-Series grant applicants and mentors with insider knowledge on the process by which these grants are reviewed, the biases that contribute to the reviews, the extent of information required in an NRSA training grant, and a deeper understanding of the exact purpose of each section of the application. New additions to this edition include coverage of other NIH grants, such as R01, R21, and P20, as well as information on significant modifications to the Biosketch and Letters of Recommendation sections. This book is a solid resource for trainees and their mentors to use as a guide when constructing F30, F31, and F32 grant applications.

Linking Environmental Exposure to Neurodevelopmental Disorders

  • 1st Edition
  • Volume 2
  • May 24, 2018
  • Michael Aschner + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 5 5 5 1 - 6
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 5 5 5 2 - 3
Advances in Neurotoxicology, Volume Two, addresses contemporary advances in neurotoxicology, with thematic volumes providing authoritative review articles on key issues in the field. Updates in this new volume include chapters on Air pollution and neurodegenerative diseases, Mercury and Parkinson’s disease, Pesticides and PD: current evidence, Aluminum and neurodegeneration, Microglia and neurodegeneration, Dietary factors, Mitochondria in neurodegeneration, and Manganese and neurodegeneration. Edited by leading experts, volumes are designed as in-depth overviews of the latest topic developments that analyze the effect of varied chemical agents on the nervous system. It is an essential resource for researchers and graduate students alike.

Inflammation and Immunity in Depression

  • 1st Edition
  • May 23, 2018
  • Bernhard Baune
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 1 0 7 3 - 7
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 1 0 7 4 - 4
Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression.

Human Embryonic Stem Cells in Development

  • 1st Edition
  • Volume 129
  • May 22, 2018
  • Ali H Brivanlou
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 4 2 5 1 - 9
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 4 3 3 4 - 9
Human Embryonic Stem Cells in Development, Volume 129, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as recapitulating pancreas development from human embryonic stem cells in a dish, modeling mammalian gastrulation with embryonic stem cells, and a section on what stem cells tell us about human germ cell biology. Each chapter is written by an international board of authors.

Novel Designs of Early Phase Trials for Cancer Therapeutics

  • 1st Edition
  • May 22, 2018
  • Shivaani Kummar + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 2 5 1 2 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 2 5 7 0 - 0
Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the integration of molecular profiling, the changes in early phase trial designs, and endpoints to optimally develop a new generation of cancer therapeutics. The book discusses topics such as statistical perspectives on cohort expansions, the role and application of molecular profiling and how to integrate biomarkers in early phase trials. Additionally, it discusses how to incorporate patient reported outcomes in phase one trials. This book is a valuable resource for medical oncologists, basic and translational biomedical scientists, and trainees in oncology and pharmacology who are interested in learning how to improve their research by using early phase trials.

Pharmacogenetics

  • 1st Edition
  • Volume 83
  • May 22, 2018
  • Kim Brosen + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 1 3 3 8 1 - 1
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 3 4 0 4 - 7
Pharmacogenetics, Volume 83, the newest volume in the Advances in Pharmacology series, presents a variety of chapters and the best authors in the field, with this release highlighting regulatory perspectives, the implementation of pharmacogenetics in everyday clinical setting, imaging in pharmacogenetics, pharmacoepidemiology in pharmacogenetics, epigenetics and micro RNA in pharmacogenetics, ethnicity in pharmacogenetics, pediatric pharmacogenetics, pharmacogenetics and adverse drug reactions, and cytochrome P450 pharmacogenetics amongst other important topics. This series presents an essential resource for pharmacologists, immunologists, and biochemists alike.

Signal Processing in Auditory Neuroscience

  • 1st Edition
  • May 22, 2018
  • Yoichi Ando
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 5 9 3 8 - 5
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 5 9 3 9 - 2
Signal Processing in Auditory Neuroscience: Temporal and Spatial Features of Sound and Speech discusses how the physical attributes of different sounds manifest in neural signals and how to tease-apart their different influences. It includes EEG/MEG as additional variables to be considered when studying neural mechanisms of auditory processing in general, specifically in speech.

Intracranial Aneurysms

  • 1st Edition
  • May 21, 2018
  • Andrew J. Ringer
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 1 7 4 0 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 1 8 8 3 - 2
Intracranial aneurysm result from complex interactions between cerebrovascular anatomy, vascular injury, and adaptive remodeling of the arterial wall and represent a cerebrovascular disorder with the potential for substantial morbidity and mortality. Most intracranial aneurysms occur in the larger arteries near the skull base, in or around the circle of Willis, but variants may appear virtually anywhere in the cerebral vasculature. The aneurysm can leak or rupture, causing life-threatening bleeding, and is the most common cause of spontaneous subarachnoid hemorrhage, the third most common form of stroke. Intracranial aneurysms affect about 1 in 10,000 people per year in the United States (approximately 27,000). Intracranial Aneurysms will address the natural history, biology, and basic management principles and treatment of aneurysms. The chapters also explore the unique features of each type or location of aneurysm while considering the medical, surgical, and endovascular options. Contributions are by members of the Endovascular Neurosurgery Research Group, a group of recognized expert neurosurgeons who specialize in cerebrovascular and endovascular management of aneurysms.

Epigenetics in Human Disease

  • 2nd Edition
  • May 18, 2018
  • Trygve O Tollefsbol
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 1 2 2 1 5 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 2 3 2 9 - 4
Epigenetics in Human Disease, Second Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, novel epigenetic approaches to treatment are also explored. Fully revised and up-to-date, this new edition discusses topics of current interest in epigenetic research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, and epigenetic mechanisms of imprinting disorders. Further sections explore online epigenetic tools and datasets, early-life programming of epigenetics in age-related diseases, the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer’s disease, respiratory diseases, and many other human maladies.

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