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Books in Clinical neuropathology

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21-24 of 24 results in All results

Mental and Neurological Public Health

  • 1st Edition
  • April 5, 2010
  • Vikram Patel + 4 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 0 2 0 2 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 3 8 1 5 2 7 - 9
Colin Mathers who leads the Global Burden of Disease group in WHO has confirmed that, in the 2004 GBD, 13.1% of global Daily Adjusted Life Years are attributable to mental or neurological disorders. While the proportions vary very widely from about 10% in low income countries to over 25% in high income countries, it is clear that there is a need for understanding how to address this issue. This volume aims to provide a comprehensive overview of the public health principles of mental and neurological disorders. This vast range of health conditions affects people across the life course, from developmental disabilities in childhood, to schizophrenia and substance abuse in adults, and dementia in old age. Despite this diversity, they all share many features: they are mostly mediated through brain dysfunction or abnormalities, are often chronic in course, typically benefit from multi-component interventions, and are amongst the most neglected conditions in global health. The volume will bring together chapters from the Psychiatry, Neurology, Substance Abuse and Child Development sections of the Encyclopedia of Public Health. The volume will be the first comprehensive text on a public health approach to this diverse group of health conditions and has no obvious competitor.

Tinnitus: Pathophysiology and Treatment

  • 1st Edition
  • Volume 166
  • October 31, 2007
  • Aage R. Moller + 4 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 3 1 6 7 - 4
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 5 4 4 6 - 4
Understanding tinnitus and treating patients with tinnitus must involve many disciplines of basic science and clinical practice. The book provides comprehensive coverage of a wide range of topics related to tinnitus including its pathophysiology, etiology and treatment. The chapters are written by researchers and clinicians who are active in the areas of basic science such as neurophysiology and neuroanatomy and in clinical specialties of psychology, psychiatry, audiology and otolaryngology.

Neurotrauma: New Insights into Pathology and Treatment

  • 1st Edition
  • Volume 161
  • July 27, 2007
  • John T. Weber + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 3 0 1 7 - 2
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 4 8 8 7 - 6
Neurotrauma is the leading cause of death and disability in young adults, and the incidence in older patients is increasing. Neurotrauma is also a field in medicine with one of the highest unmet needs. Concentrated, focused and multidisciplinary efforts are required to combat this important disease. Exciting findings from basic research open opportunities for improving treatment results. This volume presents a unique and comprehensive overview of the latest findings and insights on translational research in neurotrauma. This book should be a must for any TBI or SCI researcher interested in translating their work to the clinic, as well as to clinicians interested in the latest research findings which could provide novel treatment strategies for their patients.

Genetic Aberrancies and Neurodegenerative Disorders

  • 1st Edition
  • Volume 3
  • January 28, 2000
  • M.P. Mattson
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 8 7 6 7 3 - 3
Genetic Aberrancies and Neurodegenerative Disorders presents critical reviews and emerging findings concerning the roles of genetic mutations and polymorphisms in the pathogenesis of a range of neurological disorders including Alzheimer's and Parkinson's diseases, trinucleotide repeat disorders, stroke, epilepsy and others. This volume, written by leading experts, brings together fundamental information concerning the roles of inherited traits in the pathogenesis of different neurodegenerative disorders. In addition to providing a catalogue of the known genetic alterations that are linked to specific neurodegenerative disorders, the chapters detail the current state of understanding of the cellular and biochemical mechanisms whereby the genetic aberrancies lead to neuronal dysfunction and degeneration. The emerging picture of each disorder, painted by pathological, biochemical and molecular brushes, suggests that they share key mechanisms including increased levels of oxidative stress, perturbed ion homeostasis, mitochondrial dysfunction and apoptotic proteolytic cascades. The existence of specific molecular defects provides the opportunity to design experiments that can establish the precise pathogenic mechanism of a specific mutation or genetic risk factor. The value of this approach is exemplified by recent studies of how mutations in Cu/Zn-superoxide dismutase cause amyotrophic lateral sclerosis and how presenilin mutations result in early-onset Alzheimer's disease. A theme developed among the different chapters is that events that occur during aging predispose neurons to genetic aberrancies that promote degenerative cascades, and that specific genetic defects exert their influence on particular populations of neurons in a disorder-specific manner. The chapters in this volume will stimulate readers to generate new hypotheses concerning the pathogenic mechanisms of genetic aberrancies that can be experimentally tested.