Advances in Molecular Pathology is an annual review publication that covers the current practices and latest developments in the field of Molecular Pathology. Each issue is divided into sections for comprehensive coverage of all subspecialty areas within molecular pathology, including, Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid Tumors, and special topics on COVID-19. The Editor-in-Chief of the publication is Dr. Gregory Tsongalis, a leading expert in the field. Topics covered this year include but are not limited to: Phenotype Association and Variant Pathogenicity Prediction Tools in Genomic Analysis; The application of noninvasive prenatal screening to detect copy number variations; Next generation cytogenomics using optical mapping; Review of molecular in APL; NGS for MRD in acute leukemia; Review of emerging technologies as they pertain to infectious disease testing; Germline genetic variants that predict drug response; Nutrigenomics; PGx of hypertension; Genomic data for blood typing, specifically both through NGS and arrays; Preanalytic Variables and Tissue Stewardship for Reliable Next-Generation Sequencing (NGS) Clinical Analysis; and Cell-free nucleic acids in cancer: Current approaches, challenges, and future directions.
This issue of Clinics in Laboratory Medicine, guest edited by Dr. Vinay Subhash Mahajan, will focus on Immunology Laboratory Testing. Topics include, but are not limited to, Analysis of proteins and immunoglobulins in the clinical immunology laboratory; Antinuclear antibody tests; Serological diagnosis of rheumatoid arthritis; ANCA; Anti-phospholipid antibodies; Diagnostic pitfalls in autoantibody testing; Analysis of the complement pathway; Flow cytometric analysis of immune cell subsets; Testing of cellular immune function in immunodeficiencies; Food allergy testing; Evaluation of the immune response in transplantation; Laboratory testing in the context of biologics and cellular therapies; Testing immune-related adverse-events in cancer immunotherapy; Molecular diagnosis of inherited immune disorders; and Future of immunology lab testing.
This issue of Clinics in Laboratory Medicine, edited by Dr. Dan Milner, will focus on Global Health and Pathology. Topics include, but are not limited to: Clinical Laboratory Volunteerism, Pathologists Overseas; Anatomic Pathology Volunteerism; Funding Strategies in Research and Global Pathology; Diagnostics for Cancer and Health Systems building through pathology laboratories; Training the next pathologists in global health; Maximizing internet resources for improving pathology/lab medicine in LMICs; Pathology-based research in Africa; HIV and Cancer: Role of Pathology in success; Lymphoma and Pathology in Africa: Current approaches and future diagnostics; Laboratory Capacity as a tool for building health systems; Building Cross Country Networks for Laboratory Capacity and improvement; Lab accreditation; Practical success in Telepathology experiences in Africa; Pathology and WHO vision of the future of LMICs; Breast Cancer in LMICs: Why we need pathology and clinical trial capability to solve this challenge; Cytopathology in LMICs: why and how to integrate to capacitate healthcare; and Biorepositories and Data Cores for Research in Global Health.
This issue of Clinics in Laboratory Medicine, edited by David M. Dorfman, will cover Flow Cytometry. Topics covered in this issue include: Flow cytometric evaluation of primary immunodeficiencies; Flow cytometry of B cell neoplasms; Flow cytometry of T cell neoplasms; Flow cytometry of acute myeloid leukemias; AML minimal residual disease (MRD) assessment by flow cytometric analysis; Acute lymphoblastic leukemia minimal residual disease (MRD) assessment by flow cytometric analysis; Flow cytometric assessment of myelodysplasia and myeloproliferative neoplasms; Flow cytometry of plasma cell neoplasms, including MRD testing; Paroxysmal nocturnal hemoglobinuria (PNH) assessment by flow cytometric analysis; Mast cell disease assessment by flow cytometric analysis; Flow cytometry in pediatric hematopathology; Clinical applications of mass cytometry; Automated analysis of clinical flow cytometry data; and Cost-effective flow cytometric testing strategies.
This issue of Clinics in Laboratory Medicine, edited by Dr. Steven Billings, will cover Dermatopathology. Topics covered in this issue include Blue nevi and related lesions, sentinel lymph node biopsies in melanoma, Spitzoid melanocytic neoplasms, Tumor immunology related to melanoma, Molecular aspects of melanoma, Merkel cell carcinoma, Cutaneous Squamous Cell Carcinoma, Cutaneous T-cell lymphomas, Cutaneous B-cell lymphomas, Myeloid neoplasms, among others.
This issue of Clinics in Laboratory Medicine, edited by Drs. Nahed Ismail, A. William Pasculle, and James Snyder, will cover a wide variety of Emerging Pathogens. Topics covered in this issue include, but are not limited to West Nile Virus; Zika Virus; Ebola and Marburg Heamorrhagic Fever; Rift Valley Fever; Carbapenem Resistant Enterobacteriacae; Closteridium Difficuile; and Chikungunya, among others.
This issue of Clinics in Laboratory Medicine entitled “Risk, Error and Uncertainty: Laboratory Quality Management in the Age of Metrology” will be guest edited by Sten Westgard, James Westgard, and David Armbruster. The issue will cover a broad range of topics related to management in the laboratory including but not limited to: Metrology Perspectives; Biologic Variation Approach to Daily Laboratory; Clinical Outcome Approach to Goal Setting; Six Sigma Quality Management System; Traceability and Comparability; MU, Risk, and Sigma-metrics at Sunway; and Quality Indicators for the Total Testing Process, among others.
Ce guide, rédigé par l'ASSIM recense les principales analyses en immunologie prises en charge par la Sécurité sociale dans le cadre de la Nomenclature des Actes de Biologie Médicale (NABM).L'ouvrage développe en 6 grandes parties l'exploration : - de l'auto-immunité ; - de l'immunité humorale ; - de l'immunité cellulaire ; - en histocompatibilité et l'étude des associations HLA-maladies ; - des traitements par biomédicaments immunologiques. Chacune de ces parties est détaillée de façon pratique et synthétique sous forme de fiches, étayées de synopsis d'aide à l'exploration de la pathologie. Les points suivants sont systématiquement abordés : - la signification biologique du paramètre ; - les objectifs de l'analyse ; - la place de cette analyse dans un bilan d'exploration ; - la nature du prélèvement ; - les recommandations particulières ; - les contraintes d'acheminement ; - le mode de conservation ; - le principe méthodologique ; - le type de méthode et de mesure ; - le contrôle interne et l'évaluation externe de la qualité ; - les performances du test ; - les causes d'erreur et les limites du test.