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Nuclear Medicine and Molecular Imaging
Technology and Techniques
- 9th Edition - November 18, 2022
- Authors: David Gilmore, Kristen M. Waterstram-Rich
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 7 7 5 5 0 - 2
Purchase options
Institutional subscription on ScienceDirect
Request a sales quote- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Reviewers
- Preface
- Acknowledgments
- List of Tables
- List of Illustrations
- Section 1. Foundations
- 1. Mathematics and statistics
- Fundamentals
- Practical applications
- Statistics
- Summary
- Review questions
- Acknowledgement
- References
- 2. Cell and molecular biology
- Eukaryotic cell structure
- Control of gene expression
- The cell cycle
- Molecular basis of cancer
- Summary
- References
- 3. General chemistry and biochemistry
- Elements, compounds, and mixtures
- Laws of constant composition and multiple proportion
- Atomic weights, molecular weights, and the mole concept
- Solutions and colloids
- Chemical reactions and equations
- Double displacement reactions
- Oxidation–reduction reactions
- Electrolytic reactions
- Acids and bases
- Equilibriums and equilibrium constant
- The pH concept
- Buffer solutions
- Organic compounds
- Summary
- Suggested reading
- 4. Radiochemistry and radiopharmacology
- Production of radionuclides
- Nuclear pharmacy
- References
- 5. Radiation safety in nuclear medicine
- Radiation safety program
- Sources of radiation exposure
- Radiation regulations
- Radiation dose
- Biological effects of ionizing radiation
- Summary
- Acknowledgement
- References
- Suggested reading
- Section 2. Patient Care, Management, and Research
- 6. Patient care
- Introduction to patient care
- Diversity in health care
- Socioeconomic challenges
- Cultural competence
- Health information and HIPAA
- HIPAA overview
- Patient care
- Body mechanics
- Medication administration
- Contrast media
- Infection control
- Vital signs and patient assessment
- Emergency care
- Ancillary equipment
- Summary
- Acknowledgment
- References
- 7. Department administration and clinical research
- Health care leadership
- Health care management
- Coding and reimbursement
- Quality measures and improvement
- Accreditation
- Clinical research
- Clinical trials and studies
- Conclusion
- Summary
- References
- Suggested reading
- 8. Health informatics in imaging
- Background
- Computers in health care
- Computer hardware
- Computer software
- Image acquisition
- Image display and processing
- Region of interest
- Clinical applications
- Health information systems
- Electronic health records
- Radiology information system
- Standard operating procedures
- Future advances
- References
- Suggested reading
- Section 3. Physics and Instrumentation
- 9. Physics of nuclear medicine
- Matter
- Nucleus of an atom
- Nature of electromagnetic radiation
- Mass energy equivalence
- Units
- Modes of radioactive decay
- Mathematics of decay
- Units of radioactivity
- Decay factor and precalibration factor
- Effective half-life
- Parent–daughter radionuclide relationships
- Interaction with matter
- Attenuation and transmission of photons
- Summary
- 10. Instrumentation
- Radiation detection
- Gas-filled detectors
- Gas ionization curve
- Survey meters
- Dose calibrator
- Dose calibrator quality control
- Scintillation detectors
- Gamma cameras
- Gamma camera detector components
- Spectroscopy
- Gamma camera corrections
- Image acquisition
- Single-photon emission computed tomography
- Image quality
- Gamma camera quality control
- Scintillation counting systems
- Summary
- Acknowledgement
- References
- 11. Computed tomography physics and instrumentation
- Physics of x-rays
- X-ray tube and the production of x-rays
- Principles of computed tomography
- Computed tomography scanner design
- Multislice helical computed tomography systems
- Image data acquisition
- Computed tomography image reconstruction
- Computed tomography display
- Display of volumetric image data
- Image quality
- Computed tomography protocols
- Computed tomography artifacts
- Computed tomography radiation safety
- Computed tomography quality control
- Summary
- Acknowledgement
- Suggested reading
- 12. Positron emission tomography instrumentation
- Physics of positrons
- Production of positron emission tomography radiotracers
- Coincidence detection in positron emission tomography
- Positron emission tomography scintillation crystals
- Time-of-flight positron emission tomography
- Positron emission tomography scanner design
- Data acquisition
- Reconstruction algorithms
- Attenuation correction
- Displaying positron emission tomography data
- Image fusion
- Hybrid scanners
- Scanner calibration and quality control
- Partial-volume effect
- Quantitative image information
- Radiation safety in postron emssion tomography
- Requirements for gating and radiation therapy treatment planning
- Summary
- Suggested reading
- 13. Principles of magnetic resonance imaging
- History
- Introduction to atomic structure and basic principles
- Hydrogen nucleus
- Precession
- Resonance and excitation
- Free induction decay
- T1 and T2
- Instrumentation
- Pulse sequences and scan parameters
- Contrast media
- Safety
- Hybrid imaging: Positron emission tomography/magnetic resonance imaging
- Summary
- Suggested readings
- Section 4. Imaging Procedures and Protocols
- 14. Central nervous system
- Anatomy and physiology
- Chemistry of the brain
- Blood supply
- Radiopharmaceuticals
- Imaging techniques and protocols
- Clinical positron emission tomography and single-photon emission computed tomography studies
- Summary
- Acknowledgment
- References
- 15. Endocrine system
- Thyroid gland
- Parathyroid glands
- Neuroendocrine system
- Adrenal glands
- Summary
- References
- 16. Respiratory system
- Introduction and history
- Normal anatomy and physiology
- Pathophysiology
- Radiopharmaceuticals
- Perfusion imaging
- Ventilation–perfusion studies
- Interpretation
- Summary
- References
- 17. Cardiovascular system
- Anatomy, physiology, and pathology
- Myocardial perfusion imaging
- Positron emission tomography of the heart
- Radionuclide evaluation of ventricular function
- Imaging cardiac neurotransmission
- Summary
- Acknowledgment
- References
- Suggested reading
- 18. Gastrointestinal system
- Stomach
- Small bowel and colon
- Intestinal tract
- Liver and spleen
- Gallbladder
- Summary
- Acknolwledgment
- References
- Suggested reading
- 19. Genitourinary system
- Anatomy
- Physiology
- Radiopharmaceuticals
- Radionuclide procedures
- Measurement of effective renal plasma flow and the glomerular filtration rate
- Summary
- References
- 20. Skeletal system
- Composition of bone
- Gross structure of bone
- Joints
- Radionuclide imaging
- Instrumentation
- Spot views
- Whole-body imaging
- Single-photon emission computed tomography imaging
- Multiphase bone imaging
- Clinical aspects
- Other uses for bone imaging
- Acknowledgements
- Summary
- References
- Suggested reading
- 21. Clinical PET/CT in oncology
- Fluorine-18 fluorodeoxyglucose
- Fluorodeoxyglucose patient preparation and injection
- Positron emission tomography scan acquisition
- Normal fluorodeoxyglucose distribution
- Normal variations in fluorodeoxyglucose localization
- Fluorodeoxyglucose oncology applications
- Gallium-68 DOTATATE (NETSPOT)
- Radiopharmaceuticals
- Positron emission tomography/computed tomography oncology future trends
- Summary
- Acknowledgement
- References
- Suggested reading
- Section 5. A Summary of the More
- 22. Theranostics
- Principles of theranostics
- Theranostic radionuclides
- Traditional theranostics in nuclear medicine
- Recent and emerging theranostics in nuclear medicine and molecular imaging
- Developments in theranostics
- References
- 23. Supplementary procedures: Breast, lymph nodes, esophagus, salivary glands, inflammation, testicular, and the carbon-14 breath test
- Tumor imaging for breast cancer
- Esophagus
- Salivary glands
- Breath testing with carbon-14–labeled compounds
- Inflammatory imaging
- Testicular imaging
- Summary
- Acknowledgement
- References
- Appendix A: Percentage points and chi square distribution
- Appendix B: Radionuclides and radiopharmaceutical forms used in clinical nuclear medicine (includes research radiopharmaceuticals)
- Appendix C: Glossary
- Appendix D: Answers to Chapter 1 Mathematics and Statistics review
- Index
- No. of pages: 720
- Language: English
- Edition: 9
- Published: November 18, 2022
- Imprint: Mosby
- Paperback ISBN: 9780323775502
DG
David Gilmore
Affiliations and expertise
Program Director & Associate Professor, Nuclear Medicine Technology, MCPHS University, Boston, MassachusettsKW
Kristen M. Waterstram-Rich
Affiliations and expertise
Kristen M. Waterstram-Rich, MS, CNMT, FSNMMI-TS, Professor, Interim Associate Dean, College of Health Sciences and Technology, Rochester Institute of Technology, Rochester, NY