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Management of Metastatic Liver Tumors, An Issue of Surgical Oncology Clinics of North America
- 1st Edition, Volume 30-1 - November 20, 2020
- Editor: Michael D'Angelica
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 7 6 4 4 9 - 0
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 7 6 4 5 0 - 6
This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Michael I. D'Angelica, is devoted to Management of Metastatic Liver Tumors. Dr. D'Angelica has… Read more
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Request a sales quoteThis issue of Surgical Oncology Clinics of North America, guest edited by Dr. Michael I. D'Angelica, is devoted to Management of Metastatic Liver Tumors. Dr. D'Angelica has assembled expert authors to review the following topics: Surgical management of liver metastases of colorectal cancer; Surgical management of liver metastases of breast cancer; Surgical management of liver metastases of neuroendocrine tumors; Surgical management of liver metastases of sarcoma (including GIST); Surgical management of liver metastases of gynecologic cancers; Surgical management of liver metastases of genitourinary cancers; Surgical management of liver metastases of uveal and dermal melanoma; Is there a role for locoregional therapies for non-colorectal GI malignancies?; Intra-arterial chemotherapy for liver metastases; External beam radiation for liver metastases; Isolated hepatic perfusion for liver metastases; Debate: Improvements in systemic therapies for liver metastases will soon render locoregional treatments obsolete; Debate: Improvements in systemic therapies for liver metastases will increase the role of locoregional treatments; and more!
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Foreword
- Preface
- Surgical Management of Colorectal Cancer Liver Metastases
- Key points
- Introduction
- Long-term outcomes
- General principles of liver resection for resectable colorectal liver metastases
- Strategies for initially unresectable resectable colorectal liver metastases
- Strategies for initially resectable colorectal liver metastases
- Adjuvant chemotherapy
- Hepatectomy in the setting of extrahepatic metastases
- Posthepatectomy surveillance and salvage treatments
- The medical oncologist’s perspective
- Summary
- Surgical Management of Breast Cancer Liver Metastasis
- Key points
- Introduction
- Hepatic resection of breast cancer liver metastases
- Nonsurgical locoregional therapy for breast cancer liver metastases
- Summary
- Clinics care points
- Surgical Management of Neuroendocrine Tumor Liver Metastases
- Key points
- Introduction
- Epidemiology
- Clinical presentation
- Diagnosis
- Hepatic resection
- Liver-directed therapy
- Systemic therapies
- Summary
- Clinics care points
- Surgical Management of Sarcoma Metastatic to Liver
- Key points
- Introduction
- Systemic therapies
- Locoregional therapies
- Surgical resection
- Hepatic resection for gastrointestinal stromal tumor in the imatinib era
- Liver transplantation
- The medical oncologist’s perspective
- Summary
- Surgical Management of Gynecologic Cancers
- Key points
- Introduction
- Ovarian cancer
- Challenges of surgical trial design
- Preoperative considerations
- Surgical techniques
- Postoperative considerations
- Nonsurgical techniques
- Genetic and molecular prognostic markers
- Uterine cancer
- Cervical cancer
- Rare tumors
- Medical Oncologist Perspective
- Summary
- Surgical Management of Genitourinary Cancer Liver Metastases
- Key points
- Introduction
- Renal cell carcinoma
- Germ cell cancers
- Prostate cancer
- Bladder cancer
- Medical oncology perspective
- Summary
- An Overview of Liver Directed Locoregional Therapies
- Key points
- Introduction
- Partial liver resection
- Ablation and stereotactic radiation therapy
- Transarterial chemoembolization
- Hepatic arterial infusion chemotherapy
- Isolated hepatic perfusion and percutaneous hepatic perfusion
- Selective internal radiation therapy
- Other locoregional therapies
- Systemic therapy
- Considerations
- The medical oncologist’s perspective
- Supplementary Data
- Is There a Role for Locoregional Therapies for Non-colorectal Gastrointestinal Malignancies?
- Key points
- Introduction
- Esophageal cancer liver metastases
- Gastric cancer liver metastases
- Pancreatic cancer liver metastases
- Ampullary cancer liver metastases
- Small bowel cancer liver metastases
- Summary
- Commentary: the medical oncologist point-of-view
- Clinics care points
- Intraarterial Chemotherapy for Liver Metastases
- Key points
- Introduction
- Background of hepatic arterial infusion
- Hepatic arterial infusion as adjuvant therapy after liver resection
- Hepatic arterial infusion in the metastatic setting
- Converting unresectable to resectable liver disease with hepatic arterial infusion
- Other indications for hepatic arterial infusion—intrahepatic cholangiocarcinoma
- Summary
- External Beam Radiation Therapy for Liver Metastases
- Key points
- Introduction
- Whole-liver radiation: limitations and controversies
- Ablative liver radiation
- Role of proton therapy for ablative liver radiation
- Summary and future directions for ablative liver radiation
- Hepatic Perfusion for Diffuse Metastatic Cancer to the Liver: Open and Percutaneous Techniques
- Key points
- Introduction
- Technique for open isolated hepatic perfusion
- Results of hepatic perfusion for patients with colorectal cancer
- Results of isolated hepatic perfusion in patients with liver metastases from ocular melanoma
- Percutaneous hepatic perfusion
- Results of hepatic perfusion for patients with liver metastases from neuroendocrine tumor
- Summary
- Clinics care points
- Systemic Therapy Improvements Will Render Locoregional Treatments Obsolete for Patients with Cancer with Liver Metastases
- Key points
- Background
- Neuroendocrine tumors
- Hepatobiliary cancers
- Colorectal cancer
- Other gastrointestinal malignancies
- Summary
- Debate: Improvements in Systemic Therapies for Liver Metastases Will Increase the Role of Locoregional Treatments
- Key points
- Introduction
- Resection of liver metastases
- Improvements in systemic therapies and resection of colorectal liver metastases
- Systemic therapies for improving resectability of colorectal liver metastases
- Discussion
- No. of pages: 240
- Language: English
- Edition: 1
- Volume: 30-1
- Published: November 20, 2020
- Imprint: Elsevier
- Hardback ISBN: 9780323764490
- eBook ISBN: 9780323764506
MD
Michael D'Angelica
Affiliations and expertise
Memorial Sloan Kettering Cancer Center, Hepatopancreatobiliary Service, Cornell University, Weill Medical College, New York, NY, USA