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Central Adrenaline Neurons
Basic Aspects and Their Role in Cardiovascular Functions
- 1st Edition - January 1, 1980
- Editors: Kjell Fuxe, Menek Goldstein, Bernt Hökfelt
- Language: English
- Paperback ISBN:9 7 8 - 1 - 4 8 3 1 - 2 2 2 7 - 4
- Hardback ISBN:9 7 8 - 0 - 0 8 - 0 2 5 9 2 7 - 7
- eBook ISBN:9 7 8 - 1 - 4 8 3 1 - 5 4 6 9 - 5
Central Adrenaline Neurons: Basic Aspects and their Role in Cardiovascular Functions contains the proceedings of an international symposium held at The Wenner-Oren Center,… Read more
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Request a sales quoteCentral Adrenaline Neurons: Basic Aspects and their Role in Cardiovascular Functions contains the proceedings of an international symposium held at The Wenner-Oren Center, Stockholm on August 27-28, 1979. The purpose of the meeting is to summarize the knowledge of central adrenaline neurons and their role in cardiovascular functions. Organized into four sections, this book begins with a discussion on the morphology, biochemistry, and pharmacology of central adrenaline neurons. Subsequent sections detail the cardiovascular functions of central catecholamine neurons and the effects of centrally acting drugs on sympathetic function in normotensive and hypertensive patients. An overview lecture of the concept of α- and β-adrenergic receptors is also shown.
List of Participants
Preface
Opening Address
Section I The Morphology and Biochemistry of Central Adrenaline Neurons
The Anatomy of Central Cardiovascular Neurons
Histochemical Identification of Adrenaline Containing Cells with Special Reference to Neurons
Distribution and Characterization of PNMT and Epinephrine in the CNS
Section II The Pharmacology of Central Adrenaline Neurons
The Use of Liquid Chromatography with Electrochemical Detection for the Determination of Adrenaline and Other Biogenic Monoamines in the CNS
The Discovery of Potent Inhibitors of Phenylethanolamine N-Nethyltransferase (PNMT)
Pharmacologic Modification of Adrenaline Neurons in Rat Brain
Effect of DBH- and PNMT-Inhibition on Brain Adrenaline and Noradrenaline in Animals Exposed to Stress
Putative Regulation of Brain Norepinephrine Neurons by Epinephrine: Electrophysiological Studies
Section III Cardiovascular Functions of Central Catecholamine Neurons
Central Control of the Sympathetic Nervous System in Experimental Hypertension
Cardiovascular Effects of Piperoxan: A Putative Adrenaline Receptor Blocker
α -Adrenoreceptors and the Action of Clinidine-like Drugs
Catecholamines of the Nucleus tractus Solitarii and Blood Pressure Regulation
On the Role of Central Adrenaline Neurons in Central Cardiovascular Regulation
Effects of Antihypertensives and Other Drugs on Central Adrenaline Utilization
Adrenergic Receptor Mechanisms in the Central Nervous System in Relation to Catecholamine Neurons
Catecholamine-Stimulated Cyclic AMP Formation in Brainstem Nuclei of Normal Rats and Rats with Genetic Hypertension
The Hypotensive Actions of Centrally Administered Adrenaline
Brain Stem Adrenergic Neurons Participate in the Regulation of the Stress Response and in Genetic and Experimental Hypertension
Changes in Hypothalamic Adrenaline during Hyper- and Hypotensive States
The Role of Central Catecholamine Pathways in Spontaneous and Renal Hypertension in Rats
Central Effect of Adrenergic Compounds on Cat Respiratory Mechanisms
Overview Lecture
Radioligand Binding Studies of Adrenergic Receptors
Section IV Effects of Centrally Acting Drugs on Sympathetic Function in Normotensive and Hypertensive Patients
Elevated Plasma Adrenaline, Age-Related Decrease in Beta-Adrenoceptor-Mediated Cardiovascular Functions and Increase in Alpha-Receptor-Mediated Vasoconstriction in Essential Hypertension
The Contribution of Central and Peripheral Adrenoceptors to the Actions of Clonidine and Alpha Methyldopa in Man
Effect of Clonidine, Metoprolol and Penbutolol on Plasma Catecholamines and Renin Activity in Response to Sympathetic Stimulation in Hypertensive Patients
Subject Index
- No. of pages: 362
- Language: English
- Edition: 1
- Published: January 1, 1980
- Imprint: Pergamon
- Paperback ISBN: 9781483122274
- Hardback ISBN: 9780080259277
- eBook ISBN: 9781483154695
KF
Kjell Fuxe
Affiliations and expertise
Department of Histology, Karolinska InstitutetRead Central Adrenaline Neurons on ScienceDirect