Advances in Radiation Biology

Contributors

Preface

Contents of Other Volumes

Repair Processes for Photochemical Damage in Mammalian Cells

I. Introduction

II. Excision Repair

III. S-Phase Recovery or Postreplication Repair

IV. Photoreactivation

V. Some Implications and Conclusions

References

Enzymes Involved in the Repair of DNA

I. Introduction

II. Incision Step

III. Excision Mechanisms

IV. Pre-Reinsertion Mechanisms

V. Reinsertion of Nucleotides

VI. Sealing of the Final Phosphodiester Bond

VII. Conclusions

References

Mutation Induction in Mice

I. Introduction

II. Gametogenesis

III. Specific Locus Mutations

IV. Dominant Visible Mutations

V. Skeletal Mutations

VI. Histocompatibility Mutations

VII. Recessive Visible Mutations

VIII. Recessive Lethal Mutations

IX. Summary

References

Experimental Radiation Carcinogenesis

I. Introduction

II. General Considerations on the Significance of Animal Data for Radiation Carcinogenesis

III. Tissues at Risk

IV. Dose-Effect Relationships

V. Relative Biological Effectiveness (RBE)

VI. Effect of Dose Rate

VII. Dependence of Sensitivity on Age

VIII. Differences in Sensitivity between Strains and between Species

IX. Summary

References

Toxicology of Plutonium

I. Introduction

II. Properties of Plutonium of Biomedical Interest

III. Disposition of Plutonium in the Body

IV. Biological Effects

V. Countermeasures for Plutonium Contamination

VI. Concluding Comments

References

Effects of Ionizing Radiation on Terrestrial Plant Communities

I. Introduction

II. Methods of Study

III. Types of Effects Observed

IV. Recovery of Radiation-Damaged Plant Communities

V. Radiation Sensitivities of Plant Communities

VI. Concluding Remarks

References

The Breakage-and-Reunion Theory and the Exchange Theory for Chromosomal Aberrations Induced by Ionizing Radiations: A Short History

I. Introduction

II. Chromosomal Aberrations

III. The Development of Breakage-and-Reunion Theory

IV. The Exchange Theory

V. Implications of the Exchange Theory for Aberration Development

VI. Some Questions and Objections

VII. Further Evidence for and against the Exchange Theory

VIII. Conclusions

References

Author Index

Subject Index