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Books in Drug discovery

61-70 of 72 results in All results

Novel Anticancer Agents

  • 1st Edition
  • Alex A. Adjei + 1 more
  • Alex A. Adjei and John K. Buolamwini
  • December 13, 2005
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 0 8 8 5 6 1 - 9
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 3 7 7 5 - 7
Novel Anticancer Agents offers pertinent basic science information on strategies used for the rational design and discovery of novel anticancer agents, and, in addition, translational studies involving clinical trial design and execution with these novel, mostly cytostatic agents. This book covers basic science strategies that are being used in drug discovery and preclinical evaluation focused on novel molecular targets, as well as clinical trial methodology including clinical pharmacokinetics and imaging to address issues of efficacy evaluation of the new, relatively non-cytotoxic anticancer agents. At present, there is no book that provides such an integration of basic and clinical studies of novel anticancer agents, covering both drug discovery and translational research extensively.
Novel Anticancer Agents

Bioactive Lipids

  • 1st Edition
  • A Nicolaou + 1 more
  • A Nicolaou and G Kokotos
  • September 1, 2004
  • English
  • Hardback
    9 7 8 - 0 - 9 5 3 1 9 4 9 - 7 - 1
In Bioactive lipids, Anna Nicolaou and George Kokotos have brought together an international team of authors to discuss the nomenclature, structures, biochemistry, pharmacology and recent developments in the main classes of bioactive lipids. These lipids are essential components of the cell membrane and play many dynamic roles in mediating and controlling a wide array of cellular activities including membrane structure and organization, metabolic and gene regulation, protein structure and function, energy production, and signalling pathways.The lipid interests of scientists in the pharmaceutical and food industries are converging as the broader significance of bioactive lipids is increasingly recognized. Lipids and lipid-metabolizing enzymes are targeted for the development of new drugs. Meanwhile, functional foods, nutraceuticals and supplements already have lipids as major active ingredients. The food industry will progress from simply using lipids as ingredients, to the formulation of products that influence the synthesis, metabolism and effects of bioactive lipids in the body. These advances in applied lipid biochemistry will build on the fundamental research of lipid scientists in universities worldwide, such as those scientists contributing to Bioactive lipids.
Bioactive Lipids

Ethnomedicine and Drug Discovery

  • 1st Edition
  • Volume 1
  • M.M. Iwu + 1 more
  • M.M. Iwu and J. Wootton
  • March 1, 2002
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 3 1 2 5 - 0
The emergence of new infectious, chronic and drug resistant diseases have prompted scientists to look towards medicinal plants as agents for treatment and prevention. This book provides an interphase between ethnomedical and ethnobotanical approaches to new drug discovery and advances in biotechnology and molecular science that has made it increasingly feasible to transform traditional medicines into modern drugs. These novel approaches also raise new issues and the volume explores economic, ethical and policy considerations of drug development based on indigenous knowledge or traditional medicine.This work also features standardization and development of phytomedicines for major therapeutic indications, including emerging infectious diseases affecting developing and developed countries.The publication provides state-of-the-art information on the most innovative science, the research, the industry, the market, and the future of ethnomedicine and drug discovery.
Ethnomedicine and Drug Discovery

Trends in Drug Research III

  • 1st Edition
  • Volume 32
  • H. van der Goot
  • H. van der Goot
  • January 25, 2002
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 4 3 2 3 - 9
The tradition of setting new trends in medicinal chemistry continued at the 13th Symposium where topics included chemical and biological diversity, new paradigms in drug action, and new insights in receptor mechanisms. Other topics of great interest discussed, and included in these proceedings, are the discoveries in green chemistry, the interface between organic synthesis and biosynthesis, the growing problem of resistant micro-organisms and the possibilities to identify new, and better, antibiotics. And finally, in recent developments, the discovery of small molecules with insulin sensitizing properties.
Trends in Drug Research III

Anticancer Drug Development

  • 1st Edition
  • Bruce C. Baguley + 1 more
  • Bruce C. Baguley and David J. Kerr
  • October 15, 2001
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 0 7 2 6 5 1 - 6
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 9 0 4 4 - 1
Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided.
Anticancer Drug Development

Drug Discovery and Design

  • 1st Edition
  • Volume 56
  • Edward M. Scolnick, Frederic M. Richards + 2 more
  • Edward M. Scolnick, Frederic M. Richards, David S. Eisenberg + 1 more
  • February 21, 2001
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 9 3 3 8 - 1
Strategies to reduce medical uncertainty and build evidence have become critical to the advancement of medical knowledge and modern medical practice. As new techniques and strategies have arisen, so has the need for a current reference work. Drug Discovery and Design examines the latest research in the development of these new strategies. Some of the topics covered include angiotensin converting enzyme inhibitors, HIV protease inhibitors, PPAR agonists for diabetes, and glucan synthase antifungal agents.
Drug Discovery and Design

Trends in Drug Research II

  • 1st Edition
  • Volume 29
  • H. van der Goot
  • H. van der Goot
  • January 1, 1998
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 8 2 6 3 3 - 6
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 4 3 2 4 - 6
This volume of Pharmacochemistry Library comprises the text of invited lectures presented at the 11th Noordwijkerhout-Camerino Symposium Trends in Drug Research, held in Noordwijkerhout, The Netherlands, from 11-15 May 1997. In the programme attention has been given to the generation of new biological target systems and the generation of new lead molecules, with presentations on e.g. combinatorial chemistry, compound libraries, database search, high throughput screening and molecular biology. Other topics discussed were the perspectives for new medicines for the gastro-intestinal tract, the major developments in the search for effective anti-HIV drugs and new aspects in synthetic approaches. In a special session three topics which currently draw much attention were discussed: How to deal with the major problem of resistance against antimirobial agents? Can the apoptosis mechanism be used as a drug target? Is the newly observed phenomenon of inverse agonism a general principle and has it consequences for drug development (and use?)
Trends in Drug Research II

Advances in Drug Research

  • 1st Edition
  • Volume 30
  • Bernard Testa + 1 more
  • Bernard Testa and Urs A. Meyer
  • August 12, 1997
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 2 6 2 8 - 7
This volume continues the trend for Advances in Drug Research of shorter, but more frequent volumes. In line with the tradition of the series, chapters on general themes are interspersed with chapters on specific drug classes and targets. It will be the last volume edited by Bernard Testa and Urs A. Meyer.
Advances in Drug Research

Advances in Drug Research

  • 1st Edition
  • Volume 29
  • Bernard Testa + 1 more
  • Bernard Testa and Urs A. Meyer
  • July 21, 1997
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 2 6 7 2 - 0
This volume continues the trend for Advances in Drug Research of shorter, but more frequent volumes. In line with the tradition of the series, chapters on general themes are interspersed with chapters on specific drug classes and targets.
Advances in Drug Research

Advances in Drug Research

  • 1st Edition
  • Volume 28
  • Bernard Testa + 1 more
  • Bernard Testa and Urs A. Meyer
  • July 2, 1996
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 0 1 3 3 2 8 - 4
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 2 6 7 1 - 3
This volume continues the trend for Advances in Drug Research of shorter, but more frequent volumes. In line with the tradition of the series, chapters on general themes are interspersed with chapters on specific drug classes and targets.
Advances in Drug Research