Cell Chemical Biology

Cell Chemical Biology (originally Chemistry & Biology) is a leading interdisciplinary Cell Press journal that publishes and promotes important advances at the interface of chemistry, biology, and medicine. The journal aims to advance chemical biology by fostering innovative research that harnesses chemical and molecular principles to understand biological systems. Such research seeks to uncover the molecular mechanisms underlying cellular processes and disease, drive the discovery of novel therapeutics, and develop advanced technologies and solutions in biotechnology and biomedical sciences.

Cell Chemical Biology welcomes basic, molecular mechanistic, and translational research that provides significant conceptual advances of broad interest to researchers across the biological and biomedical sciences and related disciplines. Areas within our scope include, but are not limited to, neurobiology, immunology, cell biology, microbiology, virology, RNA biology, synthetic biology, protein engineering, genome editing, drug discovery, metabolism, and physiology.

We are particularly interested in studies that uncover molecular mechanisms underlying biological processes and disease, advance therapeutic discovery through chemical biology approaches, or develop innovative technologies to perturb, visualize, or measure biological systems. Chemical and molecular tools of interest include, but are not limited to, small molecules, nucleic acids and their modifications, antibodies, biologics, molecular probes, engineered proteins, metabolites, lipids, glycans, and post-translational modifications.

We also welcome studies reporting significant technological advances in molecular probes, sensors, tools, and methodologies, provided they demonstrate clear broad utility through proof-of-principle applications that address important questions in biological and biomedical research. Such studies should offer advances of broad interest and relevance to our readership, spanning basic scientists to clinicians.

For questions about our aims and scope, please contact us at [email protected] or reach out to our editors directly. Authors are also welcome to submit a presubmission inquiry.