LIMITED OFFER
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Zika Virus Impact, Diagnosis, Control, and Models: Volume Two: The Neuroscience of Zika examines diagnosis, vaccines, and potential therapy methods for Zika virus syndrome.… Read more
LIMITED OFFER
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Zika Virus Impact, Diagnosis, Control, and Models: Volume Two: The Neuroscience of Zika examines diagnosis, vaccines, and potential therapy methods for Zika virus syndrome. The book also details the neuroscience of Guillain-Barré syndrome, its effects and neuromuscular rehabilitation. It is designed to help readers better understand detection, therapies for Zika virus, preventative vaccines, diagnosis and associated microcephaly. Chapters on models enable further research and understanding. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions.
Section A: Zika virus: Setting the scene
1. How Zika virus emerged and spread worldwideJoselio Maria Galvao de Araujo, Manuela Sales Lima Nascimento, Paulo Marcos da Matta Guedes, and Jose Verissimo Fernandes
2. Clinical neurological spectrum of adult and congenital ZIKV infection: An overview of virology, pathogenesis, and managementWalter Sze Tung Lam, Tay Wei Xuan, Paul Ananth Tambyah, and Derek Tuck Loong Soon
3. Classification of Zika virus sequences with respect to their species and subspeciesJoilson Xavier, Stephane Tosta, Talita Adelino, Vagner Fonseca, Marta Giovanetti, and Luiz Carlos Junior Alcantara
4. Health knowledge about Zika virus: Brazil aspectsAna Luiza Vilela Borges and Raquel Zanatta Coutinho
5. Zika virus infection and replication organelle biogenesisMasashi Arakawa and Eiji Morita
Section B: Microcephaly and congenital syndromes
6. Microcephaly: Zika and other congenital infectionsLawrence Frenkel and Fernando Gomez
7. Zika and impact on the nervous system in childrenAline Almeida Bentes and Erna Geessien Kroon
8. Use of induced pluripotent stem cells and cerebral organoids to profile Zika virus infection: Features and findingsFernanda Majolo, Daniel Rodrigo Marinowic, Pamella Nunes Azevedo, Guilherme Liberato da Silva, Denise Cantarelli Machado, and Jaderson Costa DaCosta
9. Zika, miRNAs, and microcephaly genesOmar Bagasra and Ewen McLean
10. Adherens junctions and cell polarity: What they are and how they relate to congenital Zika virus syndromeFelipe A. Bustamante-Barrientos, Roberto Henzi, and Luis Federico Batiz
Section C: Guillain-Barre syndrome
11. Severe Guillain-Barre syndromeSelman Kesici and Benan Bayrakci
12. Oxidative stress in Guillain-Barre syndrome and linkage with neurologySerdar Baraklı, Sadiye Gumusyayla, Gonul Vural, and Orhan Deniz
13. Neuromuscular effects and rehabilitation in Guillain-Barre syndromeThomas Harbo and Henning Andersen
14. Postinfectious demyelinating diseases: Guillain-Barre syndrome and beyondT. Foiadelli, C. Trabatti, G.L. Marseglia, and S. Savasta
15. Linking in placental alterations, Zika virus, and Guillain-Barre syndromeKissila Rabelo, Natalia Gedeao Salomao, and Marciano Viana Paes
Section D: Case studies and short reports
16. Case study: Neuroimaging of adults and Zika virusDiogo Goulart Correa and Luiz Celso Hygino da Cruz
17. Case study: Magnetic resonance imaging and babies with Zika virus infectionDiogo Goulart Correa, Heron Werner, and Luiz Celso Hygino da Cruz
18. A case study of Guillain-Barre syndrome associated with Zika virus infectionJose Luis Soto-Hernandez, Karina Carrillo Loza, and Steven Vargas Canas
19. Clinical manifestations and outcomes of Guillain-Barre syndrome complicating Zika virus infectionAyman Alboudi and Andrew Jameson
20. Auditory brainstem in Zika virus: Insights about brain development in microcephalyDimitri Marques Abramov, Tania Regina Saad Salles, Cecilia Hedin-Pereira, Maria Elizabeth Lopes Moreira, and Vladimir V. Lazarev
Section E: Methods, biomarkers, and diagnosis
21. Magnetic resonance imaging use in detecting neurological abnormalities in Zika virus infectionDiogo Goulart Correa, Heron Werner, Osvaldo J.M. Nascimento, and Luiz Celso Hygino da Cruz Junior
22. Magnetic modulation biosensing: How it works and how it can be used to detect the Zika virusShira Roth and Amos Danielli
23. RNA extraction techniques of different body fluids for Zika virus: Blood, genitourinary specimens, saliva, and other relevant fluidsShannon E. Ronca, Bonnie E. Gulas-Wroblewski, Rebecca B. Kairis, and Kristy O. Murray
24. Saliva and urine analysis of Zika virus using loop-mediated isothermal amplification (LAMP)Talita Castro
25. Graphene-based biosensors for the detection of Zika virusAmeya Chaudhari and Prajakta Dandekar
26. The ZIKV Detect IgM Capture ELISAAlison Jane Basile and Holly R. Hughes
27. Quantum dot-based fluoroassays for ZikaJessika F.F. Ribeiro, Maria I.A. Pereira, Paulo E. Cabral Filho, Giovannia A.L. Pereira, Beate S. Santos, Goreti Pereira, and Adriana Fontes
28. Serological detection of specific IgA antibodies against Zika virus nonstructural protein 1 contributes to diagnosis of acute Zika virus infectionsKatja Steinhagen, Viola Borchardt-Loholter, Konstanze Stiba, Julia Maria Klemens, Erik Lattwein, Sandra Saschenbrecker, and Wolfgang Schlumberger
29. Serological algorithms: How they can be used for differentiating ZIKV from DENV infectionDay-Yu Chao and Gwong-Jen J. Chang
Section F: Control, vaccines, and treatments
30. Aedes aegypti and the use of natural molecules for its control: Implications in the decrease of Zika diseaseStelia Mendez-Sanchez, Duverney Chaverra-Rodriguez, and Jonny Duque
31. Strategies of Zika virus control with larvicides and their toxic potential: A focus on pyriproxyfenPatricia e Silva Alves, Maria das Dores Alves de Oliveira, Teresinha De Jesus Aguiar Dos Santos Andrade, Nerilson Marques Lima, and Joaquim Soares da Costa Junior
32. Larvicides: Plant oils and Zika controlTaruna Kaura, Naveed Pervaiz, and Abhishek Mewara
33. Pyridobenzothiazolones as anti-flavivirus agents: Impact on Zika virusMaria Sole Burali and Giuseppe Manfroni
34. The development of human monoclonal antibodies against Zika virusCui Li and Zhiheng Xu
35. The Zika virus NS1 protein as a vaccine targetMark J. Bailey and Gene S. Tan
36. Zika vaccines must prevent sexual transmissionOmar Bagasra and Ewen McLean
37. Nucleoside analogue inhibitors for Zika virus infectionJean A. Bernatchez, Michael Coste, Byron W. Purse, and Jair L. Siqueira-Neto
38. Medicinal plants as promising source of natural antiviral substances against Zika virusJuliano G. Haddad, Gilles Gadea, Philippe Despres, and Chaker El Kalamouni
39. Protein kinase C as a target in the control of viruses and implication for Zika virusA.B. Blazquez and J.C. Saiz
40. Nanotechnology applied in the control and diagnosis of Zika virus and its vectorsGabriel Augusto Pires de Souza, Livia Sacchetto, Betania Paiva Drumond, Jonatas Santos Abrahao, Tulio Cesar Rodrigues Leite, Breno de Mello Silva, Anna Carolina Toledo da Cunha Pereira, Gustavo Portela Ferreira, Luiz Cosme Cotta Malaquias, and Luiz Felipe Leomil Coelho
Section G: Models and modeling
41. Neonatal microcephaly and humanized mouse models for Zika viral pathogenesis and immunityKimberly Schmitt, Tawfik Aboellail, and Ramesh Akkina
42. Use of liver cells to discover novel peptides for anti-Zika strategiesAhmad Suhail Khazali and Rohana Yusof
43. In vivo mouse models to investigate the microcephaly associated with Zika virusRaissa R. Christoff and Patricia P. Garcez
44. Zika virus infection with primates: Fetal outcomesSunam Gurung, Rachel Jordan, James Papin, and Dean Myers
CR
CH
VP
RR
Dr Rajkumar Rajendram is a clinician scientist with a focus on internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St. Thomas Medical School, King’s College London in 2001. As an undergraduate he was awarded several prizes, merits and distinctions in pre-clinical and clinical subjects.
Dr Rajendram began his post-graduate medical training in general medicine and intensive care in Oxford. He attained membership of the Royal College of Physicians (MRCP) in 2004 and completed specialist training in acute and general medicine in Oxford in 2010. Dr Rajendram subsequently practiced as a Consultant in Acute General Medicine at the John Radcliffe Hospital, Oxford.
Dr Rajendram also trained in anaesthesia and intensive care in London and was awarded a fellowship of the Royal College of Anaesthetists (FRCA) in 2009. He completed advanced training in regional anaesthesia and intensive care. He was awarded a fellowship of the Faculty of Intensive Care Medicine (FFICM) in 2013 and obtained the European diploma of intensive care medicine (EDIC) in 2014. He then moved to the Royal Free London Hospitals as a Consultant in Intensive Care, Anaesthesia and Peri-operative Medicine. He has been a fellow of the Royal College of Physicians of Edinburgh (FRCP Edin) and the Royal College of Physicians of London (FRCP Lond) since 2017 and 2019 respectively. He is currently a Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia.
Dr Rajendram’s focus on improving outcomes from Coronavirus Disease 2019 (COVID-19) has involved research on point of care ultrasound and phenotypes of COVID-19. Dr Rajendram also recognises that nutritional support is a fundamental aspect of medical care. This is particularly important for patients with COVID-19. As a clinician scientist he has therefore devoted significant time and effort into nutritional science research and education. He is an affiliated member of the Nutritional Sciences Research Division of King’s College London and has published over 400 textbook chapters, review articles, peer-reviewed papers and abstracts.