Workbook in Practical Neonatology
- 7th Edition - January 2, 2025
- Imprint: Elsevier
- Editors: Richard Polin, Thomas Hays
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 1 4 1 5 - 1
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 1 4 3 7 - 3
Now in full color for the first time, Workbook in Practical Neonatology, Seventh Edition, uses a highly effective, case-based approach to provide practical clinical guidance on e… Read more
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Request a sales quoteNow in full color for the first time, Workbook in Practical Neonatology, Seventh Edition, uses a highly effective, case-based approach to provide practical clinical guidance on evaluation, diagnosis, and treatment of newborns. World-renowned neonatologist Dr. Richard Polin and new editor Dr. Thomas Hays lead a team of expert contributing authors who offer case studies followed by questions, answers, and explanations in every chapter. You’ll find authoritative guidance on the problems you’re most likely to see in practice, including issues regarding resuscitation, mechanical ventilation, anemia, fluid therapy, and bronchopulmonary dysplasia. The 7th Edition has been extensively revised, with new authors, new charts and graphs, and many new cases throughout.
- Organizes chapters around case studies, followed by questions and answers that require you to make diagnostic decisions and help you understand how scientific concepts apply to each clinical problem
- Guides you step-by-step through patient care with abundant diagnostic algorithms, illustrations, and decision trees
- Features a new full-color format that offers better visual clarity in design, figures, and diagrams
- Shares the expertise of many new authors throughout, as well as new editor Dr. Thomas Hays
- Provides online access to echocardiograph and fluoroscopic video clips that show you what to expect and how to proceed
- An ideal learning tool and everyday reference for practicing neonatologists, as well as students, trainees, nurses, and other clinicians
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
Neonatologists, Neonatology fellows, Neonatal/pediatric nurse practitioners
- Cover image
- Title page
- Copyright
- Contributors
- Preface
- Contents
- Video Table Of Contents
- 1 A Physiologic Approach to Neonatal Resuscitation
- Introduction
- Establishing Pulmonary Ventilation
- Case 1
- Airway Liquid Clearance Before Birth and During Labor
- Sustained Inflation During Resuscitation
- Facilitating the Cardiovascular Transition at Birth
- Managing the Asphyxiated Infant
- Summary
- References
- 2 Perinatal Hypoxia-Ischemia
- Introduction
- Conclusion
- References
- 3 Fluid and Electrolyte Management in the Newborn Intensive Care Unit
- Key principles
- Body water and fluid balance
- Suggested Readings
- CHAPTER 4 Glucose Metabolism and Neonatal Hypoglycemia
- Introduction
- Case 1
- Case 2
- Case 3
- Case 4
- Case 5
- Case 6
- Signs Associated With Neonatal Hypoglycemia
- Case 7
- Glucose Measurement
- Case 8
- Brain Injury
- Suggested Readings
- 5 Neonatal Hyperbilirubinemia
- Introduction
- Definition
- Metabolism of Bilirubin
- Case 1
- Genetics
- Heritable Aspects of Hyperbilirubinemia
- Case 2
- Measurement of Bilirubin
- Case 3
- Every TSB Value Should Be Plotted on the Bilirubin Nomogram
- Clinical Features
- Case 4
- Acute Bilirubin Encephalopathy
- Kernicterus Spectrum Disorder
- Kernicterus Spectrum Disorder: A Never Event?
- Auditory Neuropathy
- Special Investigations in Kernicterus
- Assessment and Monitoring of Hyperbilirubinemia
- Timing of TcB or TSB measurement relative to discharge and follow-up
- Treatment of Neonatal Hyperbilirubinemia
- Case 5
- Phototherapy
- Side Effects of Phototherapy
- Case 6
- Exchange Transfusion
- Intravenous Immune Globulin
- Other treatments
- Increased Hemolysis: A Risk Factor for Hyperbilirubinemia and Bilirubin Neurotoxicity
- ABO isoimmunization
- Case 7
- Increased Risk for Bilirubin Neurotoxicity Associated with Hemolysis
- AAP Recommendations Regarding Babies with Hemolysis
- G6PD deficiency: An important cause of KSD
- Case 8
- Acute Bilirubin Encephalopathy: To Exchange or Not to Exchange?
- Severe Hyperbilirubinemia Associated with G6PD Deficiency: Unpredictable and Unpreventable
- Will G6PD Screening Help?
- Moderate G6PD Deficiency Associated Hyperbilirubinemia: A Potentially High-Risk Condition
- Falsely Normal G6PD Testing
- “Nonhemolytic Jaundice”: Is There Such an Entity?
- Jaundice in Preterm Infants
- Case 9
- Pathogenesis of Jaundice in Premature Infants
- Gilbert Syndrome
- Case 10
- Crigler-Najjar Syndrome
- Breast Milk Jaundice
- Breastfeeding Jaundice
- Hypothyroidism
- Suggested ReadingS
- 6 Practical Parenteral Nutrition
- Introduction
- Case 1
- Case 2
- Case 2 (Continued)
- Case 3
- Case 3 (Continued)
- Case 4
- Case 5
- Case 6
- Case 6 (Continued)
- Case 6 (Continued)
- Case 7
- Case 8
- Case 9
- Case 8 (Continued)
- Suggested Readings
- 7 Enteral Nutrition
- Introduction
- Nutrient Requirements
- Initiation and Advancement of Enteral Nutrition
- Case 1
- Mother’s Own Milk
- Case 2
- Banked Donor Human Milk
- Case 3
- Composition of Preterm Premature Human Milk
- Case 4
- Fortification of Human Milk
- Case 5
- Growth Faltering
- Case 6
- Preterm Formula
- Case 7
- Monitoring Growth and Outcomes
- Consequences of Postnatal Growth Failure
- Case 8
- Special Considerations
- Bronchopulmonary Dysplasia
- Case 9
- Necrotizing Enterocolitis
- Postdischarge Nutrition
- Postdischarge Nutrition in the Formulated Infant
- Case 10
- Postdischarge Nutrition in the Late Preterm Infant
- Case 11
- Suggested Readings
- 8 Anemia
- Introduction
- How to Approach Anemia in Newborn
- Physiology of Oxygen Delivery
- Normal Hematological Values
- Iron Balance
- Disorders of Anemia
- Definition of Anemia
- Reduced Production
- Nutritional Anemia
- Case 1
- Isoimmunization
- Case 2
- Case 3
- Case 3 continued
- Intrapartum Hemorrhage
- Case 4
- Case 4 Continued
- Case 5
- Case 6
- Case 7
- Case 8
- Avoidance and Management of Anemia
- Iron Supplementation and Anemia of Prematurity
- Future Perspectives and Research Areas
- Suggested Readings
- 9 Respiratory Distress Syndrome
- Introduction
- Case 1
- Effective Prenatal Care for the Prevention and Mitigation of RDS
- Case 2
- Delivery Room Stabilization
- Case 3
- Case 4
- Respiratory Therapies in Early Life for the Preterm Infant With RDS
- Case 5
- Mechanical Ventilation Strategies
- Extubation
- Case 6
- Oxygen Saturation Targets
- Case 7
- Differential Diagnosis of RDS
- Initial Diagnostic Evaluation in RDS
- Case 8
- Respiratory Complications of RDS
- Conclusion
- Suggested Readings
- 10 Principles of Mechanical Ventilation
- Introduction
- Unique Challenges in Mechanical Ventilation of Newborn Infants
- Indications for Mechanical Ventilation
- Choosing the Ventilator Mode and Initial Settings
- Case Study 1: Extremely LOW-BIRTH-WEIGHT infant with respiratory distress syndrome
- Assessment of ventilator support and subsequent adjustments
- Case study 1 continued
- Case study 1 continued
- Tailoring ventilator settings and strategy to underlying pathophysiology
- Case study 2: Term infant with meconium aspiration syndrome (MAS)
- Case study 2 continued
- Case study 2 continued
- Complications of mechanical ventilation
- Case study 3: Preterm infant with RDS
- Case study 3 continued
- Case study 3 continued
- Volume-targeted ventilation
- Case study 3 continued
- Case study 3 continued
- Challenging clinical scenarios
- Case study 4: Tiny infant with RDS and metabolic acidosis
- Case study 4 continued
- Case study 4 continued
- High-frequency ventilation
- Case study 4 continued
- Case study 4 continued
- Case study 4 continued
- Suggested Readings
- CHAPTER 11 Bronchopulmonary Dysplasia
- Introduction
- Epidemiology
- Diagnostic Criteria
- Incidence of BPD
- Antenatal Determinants of BPD
- Fetal Growth Restriction and Small for Gestational Age at Birth
- Delivery Room Management of At-Risk Neonates
- NICU Management of At-Risk Neonates
- Mechanical Ventilation: Ventilator-Induced Lung Injury and Modes of Ventilation
- Oxygen Toxicity
- Infection and NEC
- Pharmacologic Therapies for the Prevention of BPD
- Noncorticosteroid therapies
- The Diagnosis of BPD Is Made: What DO We Do Next?
- Long-Term Outcomes
- Answers (case studies)
- Case 1
- Case 2
- Case 3
- Case 4
- Case 5
- Case 6
- References
- 12 Neonatal Apnea
- Case 1
- Commentary on Case 1
- Case 2
- Commentary on Case 2
- Case 3
- Commentary on Case 3
- Case 4
- Commentary on Case 4
- Case 5
- Commentary on Case 5
- Case 6
- Suggested Readings
- 13 Neonatal Sepsis
- Introduction
- Early-Onset Sepsis
- Case Study 13.1
- Case Study 13.2
- Case Study 13.3
- Late Onset Sepsis
- Case Study 13.4
- Case Study 13.5
- Case Study 13.6
- References
- 14 Patent Ductus Arteriosus
- Introduction
- Epidemiology
- Case 1
- Clinical Presentation and Diagnostic Evaluation
- Case 1 (Continued)
- CASE 2
- Prophylaxis
- Case 3
- Treatment
- Case 4
- Case 5
- Case 6
- Case 7
- Alternatives to Ductal Closure
- Case 8
- Suggested Readings
- 15 Neonatal Hypotension
- Introduction
- Introductory Case
- Understanding the Pathophysiology
- Normative Blood Pressure Data
- Differences in the premature heart
- Systemic Blood Flow Measurement/Hemodynamics
- Case Study
- Indirect Measurement of Organ Perfusion
- Direct Measurement of Organ Perfusion
- Case Study
- Pharmacology of hemodynamic agents
- Nonpharmacologic interventions
- Case Study
- Conclusion
- Suggested Readings
- 16 Congenital Heart Disease in the Newborn Period
- Introduction
- Fetal Circulation
- Case Study 1
- Screening Methods for Congenital Heart Disease
- Evaluation of Neonates for CHD
- Physical Examination
- Evaluation of the Cyanotic Newborn
- Case 2
- Case 2 (Continued)
- Case 2 (Continued)
- Cyanotic Newborn in the Newborn Nursery
- Case Study 3
- Case 3 (Continued)
- Murmur in Neonate
- Case Study 4
- Case 4 (Continued)
- Cyanotic Newborn with Respiratory Distress
- Case 5
- Case 5 (Continued)
- Neonates with Decreased Perfusion
- Case 6
- Case 6 (Continued)
- Conclusion
- Suggested Readings
- 17 Persistent Pulmonary Hypertension of the Newborn and Hypoxemic Respiratory Failure
- Introduction
- Case Study 1
- Pulmonary Vascular Transition at Birth
- Case Study 1 (Continued)
- Case Study 1 (Continued)
- Systemic Oxygen Delivery
- Assessment of Severity of PPHN/HRF
- Case Study 2
- Case Study 2 (Continued)
- Case Study 2 (Continued)
- Case Study 2 (Continued)
- Case Study 2 (Continued)
- Case Study 3
- Case Study 3 (Continued)
- Case Study 3 (Continued)
- Case Study 3 (Continued)
- Case Study 3 (Continued)
- Case Study 4
- Case Study 4 (Continued)
- Role of Echocardiography in Infants With HRF
- Case Study 4 (Continued)
- Case Study 4 (Continued)
- Case Study 5
- Case Study 5 (Continued)
- Case Study 5 (Continued)
- Case Study 6
- Case Study 6 (Continued)
- Case Study 6 (Continued)
- Case Study 6 (Continued)
- Overview of the Management of PPHN/HRF and Pulmonary Vasodilator Therapy
- Conclusion
- Suggested Readings
- 18 Neonatal Acute Kidney Injury and Early Chronic Kidney Disease
- Introduction
- Case Study 1
- Case Study 1 (Continued)
- Neonatal Hyperkalemia in the Setting of AKI
- Case Study 1 (Continued)
- Embryonic Kidney Development
- Case Study 1 (Continued)
- Case Study 2
- Renal Function in Premature and Term Neonates
- Case Study 2 (Continued)
- Case Study 2 (Continued)
- Case Study 2 (Continued)
- Case Study 2 (Continued)
- Long-Term Renal Consequences in Children With Premature Birth
- Case Study 3
- Case 3 (Continued)
- Case Study 3 (Continued)
- Case Study 3 (Continued)
- Case Study 3 (Continued)
- Suggested Readings
- 19 Neonatal Seizures
- Introduction
- Clinical History and Neurologic Examination
- Initial Diagnostic Testing for Suspected Neonatal Seizures
- Case 1
- Case 2
- Case 3
- Diagnostic Evaluation for Suspected or Confirmed Neonatal Seizures
- Case 4
- Treatment of Acute Provoked Seizures
- Case 5
- Duration of Antiseizure Medication
- Case 6
- Treating Neonatal Seizures in the Context of Therapeutic Hypothermia
- Case 7
- When Conventional Treatment Does Not Work
- Case 8
- Neonatal Onset Epilepsy
- Case 9
- Case 9 (Continued)
- Case 9 (Continued)
- Neurodevelopmental Prognosis After Neonatal Seizures
- Conclusion
- Suggested Readings
- 20 Intraventricular Hemorrhage
- Introduction
- Case
- Case
- Case
- Conclusion
- References
- CHAPTER 21 Necrotizing Enterocolitis
- Introduction
- Case 1
- Case 1 continues
- Case continued
- Clinical Presentation
- Radiographic Evaluation
- Case 2
- Pathogenesis
- Case 3
- Treatment
- Neonatal Outcomes
- Case 4
- Term Infants with NEC
- Prevention
- Conclusion
- References
- CHAPTER 22 Diagnostic Approach and Clinical Management of Metabolic Encephalopathy in Newborns
- Introduction
- Circulating Metabolic Intoxicants
- Case 1
- Case 1 Continued
- Case 1 Continued
- Case 1 Continued
- Case 1 Continued
- Brain-Specific Metabolic Intoxicants
- Case 2
- Summary
- References
- Index
- Edition: 7
- Published: January 2, 2025
- Imprint: Elsevier
- Language: English
- Paperback ISBN: 9780443114151
- eBook ISBN: 9780443114373
RP
Richard Polin
Richard Polin is William T. Speck Professor and Vice-Chair of Pediatrics, Division of Neonatology, Vagelos College of Physicians and Surgeons at Columbia University Irving Medical Center, Morgan Stanley Children’s Hospital, New York-Presbyterian, New York.
Affiliations and expertise
William T. Speck Professor and Vice-Chair of Pediatrics, Division of Neonatology, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, Morgan Stanley Children’s Hospital, New York-Presbyterian, New York, NY, USATH
Thomas Hays
Thomas Hays is Assistant Professor of Pediatrics, Division of Neonatology, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, Morgan Stanley Children’s Hospital, New York-Presbyterian, New York, New York.
Affiliations and expertise
Assistant Professor of Pediatrics, Division of Neonatology, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, Morgan Stanley Children’s Hospital, New York-Presbyterian, New York, New York