
Wise Use of Null Hypothesis Tests
A Practitioner's Handbook
- 1st Edition - October 14, 2022
- Imprint: Academic Press
- Author: Frank S Corotto
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 5 2 8 4 - 2
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 5 2 8 5 - 9
Few students sitting in their introductory statistics class learn that they are being taught the product of a misguided effort to combine two methods into one. Few students le… Read more

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Request a sales quoteFew students sitting in their introductory statistics class learn that they are being taught the product of a misguided effort to combine two methods into one. Few students learn that some think the method they are being taught should be banned. Wise Use of Null Hypothesis Tests: A Practitioner’s Handbook follows one of the two methods that were combined: the approach championed by Ronald Fisher. Fisher’s method is simple, intuitive, and immune to criticism.
Wise Use of Null Hypothesis Tests
is also a user-friendly handbook meant for practitioners. Rather than overwhelming the reader with endless mathematical operations that are rarely performed by hand, the author of Wise Use of Null Hypothesis Tests emphasizes concepts and reasoning. In Wise Use of Null Hypothesis Tests, the author explains what is accomplished by testing null hypotheses—and what is not. The author explains the misconceptions that concern null hypothesis testing. He explains why confidence intervals show the results of null hypothesis tests, performed backwards. Most importantly, the author explains the Big Secret. Many—some say all—null hypotheses must be false. But authorities tell us we should test false null hypotheses anyway to determine the direction of a difference that we know must be there (a topic unrelated to so-called one-tailed tests). In Wise Use of Null Hypothesis Tests, the author explains how to control how often we get the direction wrong (it is not half of alpha) and commit a Type III (or Type S) error.- Offers a user-friendly book, meant for the practitioner, not a comprehensive statistics book
- Based on the primary literature, not other books
- Emphasizes the importance of testing null hypotheses to decide upon direction, a topic unrelated to so-called one-tailed tests
- Covers all the concepts behind null hypothesis testing as it is conventionally understood, while emphasizing a superior method
- Covers everything the author spent 32 years explaining to others: the debate over correcting for multiple comparisons, the need for factorial analysis, the advantages and dangers of repeated measures, and more
- Explains that, if we test for direction, we are practicing an unappreciated and unnamed method of inference
Students, teachers, and researchers in biology, psychology, sociology, political science, business, epidemiology, and the health sciences. Any and all who analyze data. Any and all who are curious about the world around them.
- Cover image
- Title page
- Table of Contents
- Copyright
- Epigraph
- About the author
- What makes this book different?
- This is not a mathematics book
- Conventional books get it wrong
- Ronald Fisher got it right, and his method is simple
- What conventional books leave out
- How to use this book
- Chapter one. The conventional method is a flawed fusion
- Abstract
- 1.1 Three statisticians, two methods, and the mess that should be banned
- 1.2 Wise use and testing nulls that must be false
- 1.3 Null hypothesis testing in perspective
- Notes
- Chapter two. The point is to generalize beyond our results
- Abstract
- 2.1 Samples and populations
- 2.2 Real and hypothetical populations
- 2.3 Randomization
- 2.4 Know your population, and do not generalize beyond it
- Notes
- Chapter three. Null hypothesis testing explained
- Abstract
- 3.1 The effect of sampling error
- 3.2 The logic of testing a null hypothesis
- 3.3 We should know from the start that many null hypotheses cannot be correct
- 3.4 The traditional explanation of how to use p
- 3.5 What use of α accomplishes
- 3.6 The flawed hybrid in action
- 3.7 Criticisms of the flawed hybrid
- 3.8 We should test nulls in a way that answers the criticisms
- 3.9 How to use p and α
- 3.10 Mouse preference, done right this time
- 3.11 More p-values in action
- 3.12 What were the nulls and predictions?
- 3.13 What if p=0.05000?
- 3.14 A radical but wise way to use p
- 3.15 0.05 or .05? p or P?
- Notes
- Chapter four. How often do we get it wrong?
- Abstract
- 4.1 Distributions around means
- 4.2 Distributions of test statistics
- 4.3 Null hypothesis testing explained with distributions
- 4.4 Type I errors explained
- 4.5 Probabilities before and after collecting data
- 4.6 The null’s precision explained
- 4.7 The awkward definition of p explained
- 4.8 Errors in direction
- 4.9 Power and errors in direction
- 4.10 Manipulating power to lower p-values
- 4.11 Increasing power with one-tailed tests
- 4.12 Power and why we should we set α to 0.10 or higher
- 4.13 Power, estimated effect size, and type M errors
- 4.14 How can we know a population’s distribution?
- Notes
- Chapter five. Important things to know about null hypothesis testing
- Abstract
- 5.1 Examples of null hypotheses in proper statistics books and what they really mean
- 5.2 Categories of null hypotheses?
- 5.3 What if is important to accept the null?
- 5.4 Never do this
- 5.5 Null hypothesis testing as never explained before
- 5.6 Effect size: what is it and when is it important?
- 5.7 We should provide all results, even those not statistically “significant”
- Notes
- Chapter Six. Common misconceptions
- Abstract
- 6.1 Null hypothesis testing is misunderstood by many
- 6.2 Statistical “significance” means a difference is large enough to be important—wrong!
- 6.3 p is the probability of a type I error—wrong!
- 6.4 If results are statistically “significant,” we should accept the alternative hypothesis that something other than the null is correct—wrong!
- 6.5 If results are not statistically “significant,” we should accept the null hypothesis—wrong!
- 6.6 Based on p we should either reject or fail to reject the null hypothesis—often wrong!
- 6.7 Null hypothesis testing is so flawed that we should use confidence intervals instead—wrong!
- 6.8 Power can be used to justify accepting the null hypothesis—wrong!
- 6.9 The null hypothesis is a statement of no difference—not always
- 6.10 The null hypothesis is that there will be no significant difference between the expected and observed values—very, very wrong!
- 6.11 A null hypothesis should not be a negative statement—wrong!
- Notes
- Chapter Seven. The debate over null hypothesis testing and wise use as the solution
- Abstract
- 7.1 The debate over null hypothesis testing
- 7.2 Communicate to educate
- 7.3 Plan ahead
- 7.4 Test nulls when appropriate, not promiscuously
- 7.5 Strike the right balance between what is conventional and what is best
- 7.6 Think outside of the null hypothesis test
- 7.7 Encourage our audience to draw their own conclusions
- 7.8 Allow ourselves to draw our own conclusions
- 7.9 Strike the right balance when providing our results
- 7.10 Know the misconceptions and do not fall for them
- 7.11 Do not say that two groups “differ” or “do not differ”
- 7.12 Provide all results somehow
- 7.13 Other reformed methods of null hypothesis testing
- Notes
- Chapter Eight. Simple principles behind the mathematics and some essential concepts
- Abstract
- 8.1 Why different types of data require different types of tests
- 8.2 Simple principles behind the analysis of groups of measurements and discrete numerical data
- 8.3 Drawing conclusions when we knew all along that the null must be false
- 8.4 Degrees of freedom explained
- 8.5 Other types of t tests
- 8.6 Analysis of variance and t tests have certain requirements
- 8.7 Do not test for equal variances unless …
- 8.8 Simple principles behind the analysis of counts of observations within categories
- 8.9 Interpreting p when the null hypothesis cannot be correct
- 8.10 2×2 Designs and other variations
- 8.11 The problem with chi-squared tests
- 8.12 The reasoning behind the mathematics
- 8.13 Rules for chi-squared tests
- Notes
- Chapter Nine. The two-sample t test and the importance of pooled variance
- Abstract
- Chapter Ten. Comparing more than two groups to each other
- Abstract
- 10.1 If we have three or more samples, most say we cannot use two-sample t tests to compare them two samples at a time
- 10.2 Analysis of variance
- 10.3 The price we pay is power
- 10.4 Comparing every group to every other group
- 10.5 Comparing multiple groups to a single reference, like a control
- 10.6 Is all of this a load of rubbish?
- Notes
- Chapter Eleven. Assessing the combined effects of multiple independent variables
- Abstract
- 11.1 Independent variables alone and in combination
- 11.2 No, we may not use multiple t tests
- 11.3 We have a statistical main effect: now what?
- 11.4 We have a statistical interaction: things to consider
- 11.5 We have a statistical interaction and we want to keep testing nulls
- 11.6 Which is more important, the main effect or the interaction?
- 11.7 Designs with more than two independent variables
- 11.8 Use of analysis of variance to reduce variation and increase power
- Notes
- Chapter Twelve. Comparing slopes: analysis of covariance
- Abstract
- 12.1 Analysis of covariance
- 12.2 Use of analysis of covariance to reduce variation and increase power
- 12.3 More on the use of analysis of covariance to reduce variation and increase power
- 12.4 Use of analysis of covariance to limit the effects of a confound
- Note
- Chapter Thirteen. When data do not meet the requirements of t tests and analysis of variance
- Abstract
- 13.1 When do we need to take action?
- 13.2 Floor effects and the square root transformation
- 13.3 Floor and ceiling effects and the arcsine transformation
- 13.4 Not as simple as a floor or ceiling effect—the rank transformation
- 13.5 Making analysis of variance sensitive to differences in proportion—the logarithmic transformation
- 13.6 Nonparametric tests
- 13.7 Transforming data changes the question being asked
- Notes
- Chapter Fourteen. Reducing variation and increasing power by comparing subjects to themselves
- Abstract
- 14.1 The simple principle behind the mathematics
- 14.2 Repeated measures analysis of variances
- 14.3 Multiple comparisons tests on repeated measures
- 14.4 When subjects are not organisms
- 14.5 When repeated does not mean repeated over time
- 14.6 Pretest-posttest designs illustrate the danger of measures repeated over time
- 14.7 Repeated measures analysis of variance versus t tests
- 14.8 The problem with repeated measures
- Notes
- Chapter Fifteen. What do those error bars mean?
- Abstract
- 15.1 Confidence intervals
- 15.2 Testing null hypotheses in our heads
- 15.3 Plotting confidence intervals
- 15.4 Error bars and repeated measures
- 15.5 Plot comparative confidence intervals to make the overlap myth a reality
- Notes
- Appendix A. Philosophical objections
- Abstract
- A.1 Decades of bitter debate
- A.2 We want to know when we are wrong, not how often
- A.3 Setting α to 0.05 does not mean that 5% of all null-based decisions are wrong
- A.4 There are better ways to analyze and interpret data
- A.5 The fallacy of affirming the consequent
- A.6 Some say our method cannot be used to determine direction
- Notes
- Appendix B. How Fisher used null hypothesis tests
- Abstract
- B.1 Why follow my advice?
- B.2 Fisher tested for direction
- B.3 Others did too
- B.4 Fisher believed α should vary according to the circumstances
- B.5 Fisher came close to saying there should be no α at all
- B.6 In practice, Fisher did not categorize outcomes
- B.7 Fisher’s language answers many criticisms of null hypothesis testing
- B.8 Except for Fisher’s use of “significant”
- B.9 Fisher’s inconsistency explained
- B.10 Fisher’s thinking expressed in one word
- B.11 We have come a long way since Fisher, but the wrong way?
- Notes
- Appendix C. The method attributed to Neyman and Pearson
- Abstract
- C.1 Neyman and Pearson with Pearson
- C.2 Neyman and Pearson without Pearson
- C.3 An important limitation
- C.4 Alternatives are always infinitely numerically precise
- C.5 The method step-by-step
- C.6 The method’s influence on the flawed hybrid
- C.7 The method’s fate in the world of the flawed hybrid
- C.8 Power spreads its wings
- C.9 Neyman et al.’s method has no place in science
- Notes
- Index
- Edition: 1
- Published: October 14, 2022
- No. of pages (Paperback): 210
- No. of pages (eBook): 210
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780323952842
- eBook ISBN: 9780323952859
FC
Frank S Corotto
Frank S. Corotto earned his bachelor of science in biology at Lafayette College in Pennsylvania, his master of arts in biology at Boston University, and his doctorate in biological sciences at the University of Missouri–Columbia. He worked as a post doc at the University of Utah’s Department of Physiology then went on to teach biology at North Georgia College, later renamed North Georgia College & State University, for 17 years and at the University of North Georgia for eight years. While initially a neurobiologist, he researched in other fields including animal behavior, plant reproduction, and ciliate feeding selectivity. Because of his interest in experimental design, he discovered a primary literature on null hypothesis testing that ran counter to what is in traditional statistics books. The result is Wise Use of Null Hypothesis Tests: A Practitioner’s Handbook.
Affiliations and expertise
Professor (retired), Department of Biology, University of North Georgia, Dahlonega, Georgia, United States of America. Dr. Corotto’s formal research training is primarily in neurobiology. Later, he dabbled in many areas of biology. His primary teaching responsibility was to cover upper-division courses in cell biology and human physiology.Read Wise Use of Null Hypothesis Tests on ScienceDirect