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Use of X-Ray Crystallography in the Design of Antiviral Agents

  • 1st Edition - January 1, 1990
  • Editor: W Laver
  • Language: English
  • eBook ISBN:
    9 7 8 - 0 - 3 2 3 - 1 5 2 4 5 - 7

Use of X-Ray Crystallography in the Design of Antiviral Agents describes materials presented at an International Workshop held in Kona, Hawaii on February 6-8, 1989, which… Read more

Use of X-Ray Crystallography in the Design of Antiviral Agents

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Use of X-Ray Crystallography in the Design of Antiviral Agents describes materials presented at an International Workshop held in Kona, Hawaii on February 6-8, 1989, which discussed the use of X-ray crystallography in the design of antiviral agents. This book focuses on the approach that determines the three-dimensional structures of viruses and virus proteins with biological activity, such as computer molecular modeling. The three-dimensional structures of a number of immune complexes that involve complexes of antigen with antibodies or peptide antigens complexed with an MHC molecule are also deliberated. This text emphasizes that the three-dimensional structures allow the rational design of virus replication inhibitors that control virus infections in man and economically important domestic animals. This publication is a good reference for pharmacists, biochemists, and clinicians researching on the design of antiviral agents.