Trounce's Clinical Pharmacology for Nurses and Allied Health Professionals

19th Edition - December 10, 2019
Authors: Clive P. Page, Ruma Anand, Stephen DeWilde
Language: English
Paperback ISBN:
9 7 8 - 0 - 7 0 2 0 - 6 7 0 4 - 4
Paperback ISBN:
9 7 8 - 0 - 7 0 2 0 - 6 7 0 5 - 1
eBook ISBN:
9 7 8 - 0 - 7 0 2 0 - 6 7 2 2 - 8

Since it was first published in 1958, Trounce’s Clinical Pharmacology has been the go-to resource for health professionals who prescribe as well as administer medicatio… Read more

Trounce's Clinical Pharmacology for Nurses and Allied Health Professionals

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Since it was first published in 1958, Trounce’s Clinical Pharmacology has been the go-to resource for health professionals who prescribe as well as administer medications. Now in its nineteenth edition, the text has been fully updated to reflect the breadth and complexity of modern practice.

The book provides everything the reader needs to know when becoming a prescriber. The text is organised by body system, making it easy to follow, and covers considerations for different patient categories as well as the management of pain, cancer and infection, substance abuse and complementary and alternative medicines.

With a strong clinical orientation and written by practising clinicians, essential information is delivered in an engaging and friendly style that will ensure this book’s continued popularity with nurses and allied health professionals for many years to come.

Cover image
Title page
Table of Contents
Copyright
Contributors
1. The Use of Pharmaceuticals
Drug Development
Basic Pharmacokinetics
Absorption, Distribution and Elimination
Summary
Factors that May Modify the Efficacy and Choice of Dose of a Drug in Patients
Basic Pharmacodynamics
Summary
2. The Role of Nurses in Drug Administration
Non-Medical Prescribers
Drug History
The Prescription
Nursing Aspects of Administration
Dosage Calculations
Aids to Taking Oral Drugs
Drugs Adherence
Patient Education
Non-Prescription Drugs
3. Adverse Reactions to Drugs, Testing of Drugs and Pharmacovigilance
Types of Adverse Reactions
The Introduction and Testing of New Drugs
Formularies
Pharmacoeconomics
4. The Autonomic System
Introduction to the Autonomic Nervous System
Components of the Autonomic Nervous System
Chemical Transmission of Nerve Impulses
Sympathomimetic Drugs
Other Sympathomimetic Drugs
Adrenergic Blocking Agents
Parasympathomimetic Drugs
The Anticholinesterases
Drugs Inhibiting the Action of Acetylcholine
Drugs Affecting the Non-Adrenergic Non-Cholinergic System
Summary
5. Cardiovascular System 1: Drugs Acting on the Heart
Drug Treatment in Two Major Disorders of Heart Function
Cardiac Failure
Drugs Used in the Treatment of Cardiac Failure
Care and Treatment of Patients With Cardiac Failure
Cardiac Arrhythmias
Ablation
6. Cardiovascular System 2: Drugs Used for Blood Pressure
The Normal Control of Blood Pressure
Hypertension
How Drugs Can Lower Blood Pressure
Medicines to Lower Total Peripheral Resistance
Drugs to Lower Cardiac Output
Drugs to Decrease Blood Volume
Drugs That Act Centrally
The Treatment of Hypertension
Summary
Drugs to treat Peripheral Vascular Disease
Drugs for Patients in Shock
7. Cardiovascular system 3: Atheroma and Thrombosis – Anticoagulants and Thrombolytic Agents
Coagulation and Thrombosis
Prevention of Venous Thrombosis (Thromboprophylaxis)
Anticoagulation for Venous Thrombosis/Pulmonary Embolism
Summary
Atheroma and Arterial Thrombosis
The Hyperlipidaemias and Cholesterol
Summary
Ischaemic Heart Disease
Acute Coronary Syndrome
Treatment of Acute Coronary Syndrome
Strokes
8. Resuscitation
Background
Oral Rehydration Solutions
Intravenous Fluids
Isotonic, Hypotonic and Hypertonic Fluids
Crystalloids and Colloids
Intravenous Fluid Treatment
Drugs Used During Cardiopulmonary Resuscitation
Summary
9. The Respiratory System
Asthma
Chronic Obstructive Pulmonary Disease
Inhalation Delivery Systems
Cough Remedies
Inhalations and Mucolytic Agents
Respiratory Failure
Summary
10. Drugs Affecting the Gastrointestinal System
The Mouth
The Oesophagus and Stomach
Summary
The Intestines
The Treatment of Chronic Inflammatory Bowel Disease
Biologic Therapy
The Treatment of Constipation
Summary
Intestinal ‘Sedatives’
Pancreatic Supplements
Gallstones
Drugs and the Liver
Emetics
Antiemetics
Summary
11. Vitamins, Iron and Treatment of Anaemia
Vitamins
Iron Deficiency Anaemia
Drugs Used to Treat Other Anaemias
Summary
12. Drugs Affecting the Kidney
Introduction to Diuretics
Diuretic Drugs
Making Urine Alkaline
Summary
13. Drugs Used for the Treatment of Rheumatological Conditions: Treatment of Arthritis and Gout
The Acute Inflammatory Reaction
Non-Steroidal Antiinflammatory Drugs
Summary
Rheumatoid Arthritis (and Other Rheumatic Disorders)
Summary
Gout
Summary
14. Endocrine system 1: The Hypothalamus and Pituitary
Hormones
The Hypothalamic–Pituitary Axis
Control of Pituitary Hormone Release
The Hypothalamus and Obesity
Summary
15. Endocrine system 2: Hormones and Metabolism – Thyroid and Parathyroid Disorders
The Thyroid Gland and Thyroid Hormones
Abnormalities of Thyroid Function
Treatment of Thyrotoxicosis
Summary
Bone Metabolism, the Parathyroid Glands and Calcium
The Parathyroid Glands and Parathyroid Hormone
Hypercalcaemia
Calcitonin
Osteoporosis and Its Treatment
Summary
16. Endocrine system 3: Hormones and Metabolism – Diabetes
The Pancreas
Insulin
Diabetes Mellitus
Treatment of Type 1 Diabetes
Management of Patients with Type 2 Diabetes Mellitus
Glucagon
The Nurse and the Patient with Diabetes At Home
Appetite Suppression and Obesity
Summary
17. Endocrine system 4: Hormones and Metabolism – The Adrenal Glands
The Adrenal Glands
The Cortex
Glucocorticoid Hormones
The Adrenal Medulla
Summary
18. Endocrine system 5: Hormones and Reproduction
The Female Sex Hormones
The Male Sex Hormones
Summary
The Oestrogens
Oral Contraception
The UK Medical Eligibility Criteria
Intrauterine System
Summary
Hormone Replacement Therapy
Summary
Drugs That Affect Uterine Smooth Muscle
Summary
Male Sex Hormones
19. Nervous System 1: General Anaesthesia and Local Anaesthetics
History
Preoperative Assessment of the Patient
Premedication
Maintenance of Anaesthesia
The Neuromuscular Junction
Malignant Hyperpyrexia
Local Anaesthetics
Summary
20. Nervous system 2: Opioid Analgesics
The Perception of Pain
Drugs That Relieve Pain
Analgesics for the Treatment of Acute Pain
Opioid Analgesics
Opioid Agonists
Opioid Partial Agonists
Opioid Antagonists
Summary
Analgesics for Terminal Disease
Terminal Care Services and the Pain Control Team
21. Drugs Used in Neurological Diseases: Migraine, Epilepsy and Parkinson’s Disease
Migraine
Epilepsy
Summary
Parkinson’s Disease
22. Drugs Used in Psychiatric Disorders: Antipsychotics, Antidepressants, Anxiolytics, Hypnotics and Anti-dementia drugs
Introduction
Types of Mental Illness
Brain Neurotransmitters and Psychiatric Disorders
Administration of Drugs to Psychiatric Patients
Antipsychotic Drugs
First Generation Antipsychotic Drugs
Second Generation Antipsychotic Drugs
Treatment of Schizophrenia
Acute Confusional State
Anxiety
Anxiolytic Drugs
Insomnia
Sedatives Prior to Minor Procedures
Depression
Electroconvulsive Therapy
Mania/Bipolar Disorder
Dementia
Attention Deficit Hyperactivity Disorder
Jet Lag
Summary
23. Drug Dependence and Drug Abuse
Introduction
Alcohol
Opioids (see chapter 20)
Cocaine
Amphetamines and Ecstasy
Barbiturates
Cannabis (Marijuana)
Volatile Solvents
Hallucinogens
Nicotine
Caffeine
Summary
24. Drugs Used for Dermatological Conditions
Dermatological Diagnosis and Treatment
Emollients
Types of Skin Applications
Ingredients in Preparations
Treatment of Some Common Skin Conditions
Application of Skin Preparations
Drug Eruptions
Summary
25. Drugs Used For Ear, Nose and Throat Disorders
The Ear
The Nose
The Throat
The Mouth
Summary
26. Antibacterials
Introduction
How Antibacterial Substances Work
Gram-Positive and Gram-Negative Bacteria
Choosing an Antibiotic
Sulphonamides
Nitrofurans
Quinolones
β-Lactam Antibiotics
Aminoglycosides
Tetracyclines
Chloramphenicol
Macrolides
Glycopeptides
Miscellaneous Antibiotics
Tuberculosis
Bacterial Resistance to Antibiotics
Antimicrobial Stewardship
Antibiotic Drugs in the Treatment of Common Infections
Prevention of Surgical Site Infection
Routine Surveillane of Healthcare-Associated Infections
27. Antivirals: Treatments for HIV, Hepatitis and Influenza
The Virus
Antiviral Agents
Cytomegalovirus
Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS)
Summary
Hepatitis B and Hepatitis C Virus
Influenza
Summary
Antifungal Agents
Summary
28. Vaccines
The Immune Reaction
Active Immunization
Passive Immunization
Administration of Serum
Antisera
Vaccines
Contraindications to Immunization
COVID-19
Drugs That Block the Immune Reaction
Summary
29. Drugs Used in the Treatment of Malignant Diseases
Introduction
Approaches to Cancer Treatment
Drug Treatments for Cancer
Targeted Therapies
Immunotherapy
Sex Hormones and Hormone Antagonists
Combination Therapy
Adjuvant Treatment
Palliative Chemotherapy
Practical Points
Long-Term Risks of the Use of Cytotoxic Drugs
The Role of the Nurse in Cancer Chemotherapy
30. Drugs Used in the Treatment of Tropical Diseases
Introduction
Preparations and Bite Avoidance
Diseases and Infestations
Anthelmintics
31. Drugs Used in the Treatment of Ophthalmological Diseases
Structure of the Eye
Types of Drugs Used
Antibacterial Agents
Antifungal Drugs
Antiviral Agents
Antiprotozoan Drugs
Drugs Affecting Pupil Size
The Treatment of Glaucoma
The Treatment of Age-Related Macular Degeneration
Local Anaesthetics
Ocular Lubricants
Stains Used in Ophthalmology
Drugs with Adverse Effects on the Eye
Summary
32. Special Considerations in Drug Use: Pregnancy, Paediatrics and the Older Patient
Introduction
Drugs in Pregnancy
Drugs in Newborn Infants
Breastfeeding and Drugs
Dosage of Medcines in Children
Use of Drugs in the Older Patient
Palliative Care
33. Toxicity of Drugs and Treatment
Introduction
General Management
Treatment
Individual Poisons
Chelating Agents
General Information
34. Herbal Medicines and Homeopathy
Herbal Medicines
Homeopathy
Appendix. Biologic Agents
Glossary
Index

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Trounce's Clinical Pharmacology for Nurses and Allied Health Professionals

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Save 50% on book bundles

Institutional subscription on ScienceDirect

Clive P. Page

Stephen DeWilde