Trounce's Clinical Pharmacology for Nurses and Allied Health Professionals
- 19th Edition - December 10, 2019
- Imprint: Elsevier
- Authors: Clive P. Page, Ruma Anand, Stephen DeWilde
- Language: English
- Paperback ISBN:9 7 8 - 0 - 7 0 2 0 - 6 7 0 4 - 4
- Paperback ISBN:9 7 8 - 0 - 7 0 2 0 - 6 7 0 5 - 1
- eBook ISBN:9 7 8 - 0 - 7 0 2 0 - 6 7 2 2 - 8
Since it was first published in 1958, Trounce’s Clinical Pharmacology has been the go-to resource for health professionals who prescribe as well as administer medicatio… Read more
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Request a sales quoteSince it was first published in 1958, Trounce’s Clinical Pharmacology has been the go-to resource for health professionals who prescribe as well as administer medications. Now in its nineteenth edition, the text has been fully updated to reflect the breadth and complexity of modern practice.
The book provides everything the reader needs to know when becoming a prescriber. The text is organised by body system, making it easy to follow, and covers considerations for different patient categories as well as the management of pain, cancer and infection, substance abuse and complementary and alternative medicines.
With a strong clinical orientation and written by practising clinicians, essential information is delivered in an engaging and friendly style that will ensure this book’s continued popularity with nurses and allied health professionals for many years to come.
- Easy navigation makes learning enjoyable
- Hot topics including cardiology, rheumatology and the use of targeted therapies in cancer keep the reader up to date
- Learning Objectives, Summary Boxes, Revision Tips and Hints make this suitable for exam preparation
- Updated to include discussion of the expanding role of professionals in prescribing drugs and latest changes in legislation and guidelines
- Extensive glossary for those new to prescribing
Pre-registration and post-registration nurses
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- 1. The Use of Pharmaceuticals
- Drug Development
- Basic Pharmacokinetics
- Absorption, Distribution and Elimination
- Summary
- Factors that May Modify the Efficacy and Choice of Dose of a Drug in Patients
- Basic Pharmacodynamics
- Summary
- 2. The Role of Nurses in Drug Administration
- Non-Medical Prescribers
- Drug History
- The Prescription
- Nursing Aspects of Administration
- Dosage Calculations
- Aids to Taking Oral Drugs
- Drugs Adherence
- Patient Education
- Non-Prescription Drugs
- 3. Adverse Reactions to Drugs, Testing of Drugs and Pharmacovigilance
- Types of Adverse Reactions
- The Introduction and Testing of New Drugs
- Formularies
- Pharmacoeconomics
- 4. The Autonomic System
- Introduction to the Autonomic Nervous System
- Components of the Autonomic Nervous System
- Chemical Transmission of Nerve Impulses
- Sympathomimetic Drugs
- Other Sympathomimetic Drugs
- Adrenergic Blocking Agents
- Parasympathomimetic Drugs
- The Anticholinesterases
- Drugs Inhibiting the Action of Acetylcholine
- Drugs Affecting the Non-Adrenergic Non-Cholinergic System
- Summary
- 5. Cardiovascular System 1: Drugs Acting on the Heart
- Drug Treatment in Two Major Disorders of Heart Function
- Cardiac Failure
- Drugs Used in the Treatment of Cardiac Failure
- Care and Treatment of Patients With Cardiac Failure
- Cardiac Arrhythmias
- Ablation
- 6. Cardiovascular System 2: Drugs Used for Blood Pressure
- The Normal Control of Blood Pressure
- Hypertension
- How Drugs Can Lower Blood Pressure
- Medicines to Lower Total Peripheral Resistance
- Drugs to Lower Cardiac Output
- Drugs to Decrease Blood Volume
- Drugs That Act Centrally
- The Treatment of Hypertension
- Summary
- Drugs to treat Peripheral Vascular Disease
- Drugs for Patients in Shock
- 7. Cardiovascular system 3: Atheroma and Thrombosis – Anticoagulants and Thrombolytic Agents
- Coagulation and Thrombosis
- Prevention of Venous Thrombosis (Thromboprophylaxis)
- Anticoagulation for Venous Thrombosis/Pulmonary Embolism
- Summary
- Atheroma and Arterial Thrombosis
- The Hyperlipidaemias and Cholesterol
- Summary
- Ischaemic Heart Disease
- Acute Coronary Syndrome
- Treatment of Acute Coronary Syndrome
- Strokes
- 8. Resuscitation
- Background
- Oral Rehydration Solutions
- Intravenous Fluids
- Isotonic, Hypotonic and Hypertonic Fluids
- Crystalloids and Colloids
- Intravenous Fluid Treatment
- Drugs Used During Cardiopulmonary Resuscitation
- Summary
- 9. The Respiratory System
- Asthma
- Chronic Obstructive Pulmonary Disease
- Inhalation Delivery Systems
- Cough Remedies
- Inhalations and Mucolytic Agents
- Respiratory Failure
- Summary
- 10. Drugs Affecting the Gastrointestinal System
- The Mouth
- The Oesophagus and Stomach
- Summary
- The Intestines
- The Treatment of Chronic Inflammatory Bowel Disease
- Biologic Therapy
- The Treatment of Constipation
- Summary
- Intestinal ‘Sedatives’
- Pancreatic Supplements
- Gallstones
- Drugs and the Liver
- Emetics
- Antiemetics
- Summary
- 11. Vitamins, Iron and Treatment of Anaemia
- Vitamins
- Iron Deficiency Anaemia
- Drugs Used to Treat Other Anaemias
- Summary
- 12. Drugs Affecting the Kidney
- Introduction to Diuretics
- Diuretic Drugs
- Making Urine Alkaline
- Summary
- 13. Drugs Used for the Treatment of Rheumatological Conditions: Treatment of Arthritis and Gout
- The Acute Inflammatory Reaction
- Non-Steroidal Antiinflammatory Drugs
- Summary
- Rheumatoid Arthritis (and Other Rheumatic Disorders)
- Summary
- Gout
- Summary
- 14. Endocrine system 1: The Hypothalamus and Pituitary
- Hormones
- The Hypothalamic–Pituitary Axis
- Control of Pituitary Hormone Release
- The Hypothalamus and Obesity
- Summary
- 15. Endocrine system 2: Hormones and Metabolism – Thyroid and Parathyroid Disorders
- The Thyroid Gland and Thyroid Hormones
- Abnormalities of Thyroid Function
- Treatment of Thyrotoxicosis
- Summary
- Bone Metabolism, the Parathyroid Glands and Calcium
- The Parathyroid Glands and Parathyroid Hormone
- Hypercalcaemia
- Calcitonin
- Osteoporosis and Its Treatment
- Summary
- 16. Endocrine system 3: Hormones and Metabolism – Diabetes
- The Pancreas
- Insulin
- Diabetes Mellitus
- Treatment of Type 1 Diabetes
- Management of Patients with Type 2 Diabetes Mellitus
- Glucagon
- The Nurse and the Patient with Diabetes At Home
- Appetite Suppression and Obesity
- Summary
- 17. Endocrine system 4: Hormones and Metabolism – The Adrenal Glands
- The Adrenal Glands
- The Cortex
- Glucocorticoid Hormones
- The Adrenal Medulla
- Summary
- 18. Endocrine system 5: Hormones and Reproduction
- The Female Sex Hormones
- The Male Sex Hormones
- Summary
- The Oestrogens
- Oral Contraception
- The UK Medical Eligibility Criteria
- Intrauterine System
- Summary
- Hormone Replacement Therapy
- Summary
- Drugs That Affect Uterine Smooth Muscle
- Summary
- Male Sex Hormones
- 19. Nervous System 1: General Anaesthesia and Local Anaesthetics
- History
- Preoperative Assessment of the Patient
- Premedication
- Maintenance of Anaesthesia
- The Neuromuscular Junction
- Malignant Hyperpyrexia
- Local Anaesthetics
- Summary
- 20. Nervous system 2: Opioid Analgesics
- The Perception of Pain
- Drugs That Relieve Pain
- Analgesics for the Treatment of Acute Pain
- Opioid Analgesics
- Opioid Agonists
- Opioid Partial Agonists
- Opioid Antagonists
- Summary
- Analgesics for Terminal Disease
- Terminal Care Services and the Pain Control Team
- 21. Drugs Used in Neurological Diseases: Migraine, Epilepsy and Parkinson’s Disease
- Migraine
- Epilepsy
- Summary
- Parkinson’s Disease
- 22. Drugs Used in Psychiatric Disorders: Antipsychotics, Antidepressants, Anxiolytics, Hypnotics and Anti-dementia drugs
- Introduction
- Types of Mental Illness
- Brain Neurotransmitters and Psychiatric Disorders
- Administration of Drugs to Psychiatric Patients
- Antipsychotic Drugs
- First Generation Antipsychotic Drugs
- Second Generation Antipsychotic Drugs
- Treatment of Schizophrenia
- Acute Confusional State
- Anxiety
- Anxiolytic Drugs
- Insomnia
- Sedatives Prior to Minor Procedures
- Depression
- Electroconvulsive Therapy
- Mania/Bipolar Disorder
- Dementia
- Attention Deficit Hyperactivity Disorder
- Jet Lag
- Summary
- 23. Drug Dependence and Drug Abuse
- Introduction
- Alcohol
- Opioids (see chapter 20)
- Cocaine
- Amphetamines and Ecstasy
- Barbiturates
- Cannabis (Marijuana)
- Volatile Solvents
- Hallucinogens
- Nicotine
- Caffeine
- Summary
- 24. Drugs Used for Dermatological Conditions
- Dermatological Diagnosis and Treatment
- Emollients
- Types of Skin Applications
- Ingredients in Preparations
- Treatment of Some Common Skin Conditions
- Application of Skin Preparations
- Drug Eruptions
- Summary
- 25. Drugs Used For Ear, Nose and Throat Disorders
- The Ear
- The Nose
- The Throat
- The Mouth
- Summary
- 26. Antibacterials
- Introduction
- How Antibacterial Substances Work
- Gram-Positive and Gram-Negative Bacteria
- Choosing an Antibiotic
- Sulphonamides
- Nitrofurans
- Quinolones
- β-Lactam Antibiotics
- Aminoglycosides
- Tetracyclines
- Chloramphenicol
- Macrolides
- Glycopeptides
- Miscellaneous Antibiotics
- Tuberculosis
- Bacterial Resistance to Antibiotics
- Antimicrobial Stewardship
- Antibiotic Drugs in the Treatment of Common Infections
- Prevention of Surgical Site Infection
- Routine Surveillane of Healthcare-Associated Infections
- 27. Antivirals: Treatments for HIV, Hepatitis and Influenza
- The Virus
- Antiviral Agents
- Cytomegalovirus
- Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS)
- Summary
- Hepatitis B and Hepatitis C Virus
- Influenza
- Summary
- Antifungal Agents
- Summary
- 28. Vaccines
- The Immune Reaction
- Active Immunization
- Passive Immunization
- Administration of Serum
- Antisera
- Vaccines
- Contraindications to Immunization
- COVID-19
- Drugs That Block the Immune Reaction
- Summary
- 29. Drugs Used in the Treatment of Malignant Diseases
- Introduction
- Approaches to Cancer Treatment
- Drug Treatments for Cancer
- Targeted Therapies
- Immunotherapy
- Sex Hormones and Hormone Antagonists
- Combination Therapy
- Adjuvant Treatment
- Palliative Chemotherapy
- Practical Points
- Long-Term Risks of the Use of Cytotoxic Drugs
- The Role of the Nurse in Cancer Chemotherapy
- 30. Drugs Used in the Treatment of Tropical Diseases
- Introduction
- Preparations and Bite Avoidance
- Diseases and Infestations
- Anthelmintics
- 31. Drugs Used in the Treatment of Ophthalmological Diseases
- Structure of the Eye
- Types of Drugs Used
- Antibacterial Agents
- Antifungal Drugs
- Antiviral Agents
- Antiprotozoan Drugs
- Drugs Affecting Pupil Size
- The Treatment of Glaucoma
- The Treatment of Age-Related Macular Degeneration
- Local Anaesthetics
- Ocular Lubricants
- Stains Used in Ophthalmology
- Drugs with Adverse Effects on the Eye
- Summary
- 32. Special Considerations in Drug Use: Pregnancy, Paediatrics and the Older Patient
- Introduction
- Drugs in Pregnancy
- Drugs in Newborn Infants
- Breastfeeding and Drugs
- Dosage of Medcines in Children
- Use of Drugs in the Older Patient
- Palliative Care
- 33. Toxicity of Drugs and Treatment
- Introduction
- General Management
- Treatment
- Individual Poisons
- Chelating Agents
- General Information
- 34. Herbal Medicines and Homeopathy
- Herbal Medicines
- Homeopathy
- Appendix. Biologic Agents
- Glossary
- Index
- Edition: 19
- Published: December 10, 2019
- Imprint: Elsevier
- No. of pages: 568
- Language: English
- Paperback ISBN: 9780702067044
- Paperback ISBN: 9780702067051
- eBook ISBN: 9780702067228
CP
Clive P. Page
Affiliations and expertise
Director, Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, UKSD
Stephen DeWilde
Dr Stephen DeWilde is Senior Lecturer in General Practice in the Population Health Research Institute. He is interested in primary care databases; their development and preparation for research purposes, and their use in epidemiological research.
Dr DeWilde works part time as a general practitioner (GP) and is involved in GP education and GP information technology. His research has focused on cardiovascular epidemiology, but he has also worked on diverse areas, including polypharmacy in the elderly, mental health and ocular disease.
Affiliations and expertise
Senior Lecturer in General Practice in the Population Health Research Institute, St George's, University of London.