Trichinella and Trichinellosis
- 1st Edition - July 22, 2021
- Imprint: Academic Press
- Editor: Fabrizio Bruschi
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 1 2 0 9 - 7
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 1 2 6 7 - 7
Trichinella and Trichinellosis provides an up-to-date account of the nematode Trichinella spp., including infections and diseases caused by this parasite in both animals and hum… Read more
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Trichinella and Trichinellosis provides an up-to-date account of the nematode Trichinella spp., including infections and diseases caused by this parasite in both animals and humans. This book will fill the long gap in time during which an exhaustive monograph on this subject has been missing in the international literature. The chapters have been written by the most prolific researchers in the world on the different aspects of Trichinella and trichinellosis.
This book serves as an original resource for research on Trichinella and trichinellosis, exploring cutting-edge advances on such parasites and the infections they cause.
This book will be a valuable resource for students, biologists, epidemiologists, veterinarians, physicians, and scientists involved in the study of the parasites of the Trichinella genus and their related diseases. It will be particularly helpful for those who are beginning their research in this fascinating field.
- Offers a broad overview on the parasites belonging to the Trichinella genus
- Presents recent cutting-edge advances on this zoonotic parasite, focusing on the molecular epidemiology, systematics of the parasite, clinical aspects of the diseases, and the roadmap to the control of infection in domestic pigs
- Discusses ground-breaking approaches designed to meet the medical needs in trichinellosis
Undergraduate and graduate students, scientists and professors in medical and veterinary immunology, infectious and tropical diseases, veterinary medicine and public health
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- List of contributors
- Foreword
- Preface
- Acknowledgments
- Part I: General aspects
- Chapter 1. History of the parasite and disease
- Abstract
- 1.1 History of the discovery
- 1.2 Paleopathological findings
- 1.3 Conclusions
- Acknowledgment
- References
- Chapter 2. The genetics of Trichinella populations: a study in contrasts
- Abstract
- 2.1 Species of Trichinella harbor distinct levels of genetic variability, reflecting contrasting histories
- 2.2 Related species of Trichinella maintain distinctions despite occasional gene flow among them
- 2.3 Extreme inbreeding in Trichinella typically engenders highly uniform infections
- 2.4 Work remains to establish efficient, robust tools for outbreak tracing where populations are highly inbred
- 2.5 Population genetics sheds light on the origins of current challenges
- References
- Chapter 3. Taxonomy of the Trichinella genus
- Abstract
- 3.1 Introduction
- 3.2 Expansion of the single species concept of Trichinella
- 3.3 The taxonomy of the genus Trichinella
- 3.4 Phylogeny of the Trichinella genus
- 3.5 Zoogeography of the Trichinella genus
- 3.6 The key for Trichinella taxon identification
- 3.7 The Trichinella biobank
- 3.8 The importance of Trichinella taxon identification
- 3.9 Concluding remarks and future prospective
- References
- Chapter 4. Biology of Trichinella
- Abstract
- 4.1 Introduction
- 4.2 Overall structure
- 4.3 Life cycle
- 4.4 Muscle larvae
- 4.5 Adult worm
- 4.6 Newborn larvae of Trichinella
- 4.7 Body wall of Trichinella
- 4.8 Locomotion and movement
- 4.9 Protection
- 4.10 Exocrine system
- 4.11 Cyst (the parasite nurse cell complex or capsule)
- References
- Chapter 5. Proteomics of Trichinella
- Abstract
- 5.1 Global proteomic analysis of Trichinella
- 5.2 Functional characterization of Trichinella proteins
- References
- Chapter 6. Epidemiology
- Abstract
- 6.1 Introduction
- 6.2 Trichinella hosts
- 6.3 Trichinella cycles
- 6.4 Trichinella spp. and the international trade of live animals and meat
- 6.5 Trichinella infections in humans
- 6.6 Trichinella and trichinellosis in the world
- 6.7 Conclusions
- References
- Part II: Immunology and immunopathology
- Chapter 7. Immunity to Trichinella
- Abstract
- 7.1 Introduction
- 7.2 Primary and secondary infections: kinetics and resistance
- 7.3 Mechanisms of immunity to enteral stages of infection
- 7.4 Immunity to parenteral stages of infection
- 7.5 Mechanisms of immunity in nonrodent hosts
- 7.6 Conclusions
- Acknowledgments
- References
- Chapter 8. Immunopathology of myositis, myocarditis, and central nervous system involvement in trichinellosis
- Abstract
- 8.1 Introduction
- 8.2 Conclusions
- References
- Part III: The disease
- Chapter 9. Trichinellosis in animals
- Abstract
- 9.1 Introduction
- 9.2 Swine
- 9.3 Horse
- 9.4 Ruminants
- 9.5 Carnivores
- 9.6 Nonhuman primates
- 9.7 Birds
- 9.8 Reptiles
- 9.9 Conclusions
- References
- Chapter 10. Clinical picture and diagnosis of human trichinellosis
- Abstract
- 10.1 Infectious doses, severity of the disease, and clinical forms
- 10.2 Description of the moderately severe form
- 10.3 Severe forms and complications
- 10.4 Other forms
- 10.5 Biological diagnosis
- 10.6 Circumstances of diagnosis
- 10.7 Conclusion
- References
- Part IV: Diagnosis and treatment
- Chapter 11. Anatomical pathology
- Abstract
- 11.1 Introduction
- 11.2 Skeletal muscle involvement
- 11.3 Electron microscopy data
- 11.4 More about the nurse cell
- 11.5 Myocardial involvement
- 11.6 Central nervous system involvement
- 11.7 Lung involvement
- 11.8 Renal involvement
- 11.9 Liver involvement
- 11.10 Small bowel involvement
- 11.11 Conclusion
- References
- Further reading
- Chapter 12. Immunodiagnosis
- Abstract
- 12.1 Introduction
- 12.2 Source of antigens
- 12.3 Immunodiagnostic assays
- 12.4 Evaluations and recommendations
- 12.5 Conclusions
- 12.6 Protocol for enzyme-linked-immunosorbent-assay
- References
- Chapter 13. Molecular methods for identifying and diagnosing Trichinella; from historical perspectives to the “-omics” revolution
- Abstract
- 13.1 Introduction
- 13.2 Identifying Trichinella genotypes; prepolymerase chain reaction technologies
- 13.3 Polymerase chain reaction and identifying Trichinella genotypes
- 13.4 DNA sequencing
- 13.5 Transcriptomics, genomics, and Trichinella
- 13.6 The future
- References
- Chapter 14. Treatment
- Abstract
- 14.1 Available antiparasitic drugs
- 14.2 Control of inflammation—role of glucocorticosteroids
- 14.3 Special recommendations
- References
- Part V: Control measures
- Chapter 15. Preharvest and postharvest control of Trichinella in meat
- Abstract
- 15.1 Introduction
- 15.2 Preharvest prevention of infection
- 15.3 Postharvest prevention
- 15.4 Postharvest processing
- 15.5 Trade
- 15.6 Summary
- References
- Chapter 16. Antigenic shift during Trichinella cycle, consequences for vaccine developments
- Abstract
- 16.1 Introduction
- 16.2 Evaluation of anti-Trichinella vaccine candidates: toward a proof of concept?
- 16.3 Vaccine developments: from irradiated parasites to antigen pools from Trichinella sp
- 16.4 Purification of protein with monoclonal antibodies and new vaccination approaches
- 16.5 From “wet lab to dry lab” to select candidate vaccines
- 16.6 Caveats and future developments of anti-Trichinella vaccines
- 16.7 Future developments for a vaccine against Trichinella, a foodborne zoonotic parasite
- Acknowledgments
- References
- Index
- Edition: 1
- Published: July 22, 2021
- Imprint: Academic Press
- No. of pages: 554
- Language: English
- Paperback ISBN: 9780128212097
- eBook ISBN: 9780128212677
FB
Fabrizio Bruschi
Fabrizio Bruschi is a professor of parasitology and parasitic diseases at the School of Medicine, Università di Pisa, Italy. Prof. Bruschi has been a member of the International Commission on trichinellosis since 1988. Additionally, he is currently President of the Italian Society of Parasitology (SoIPa). Furthermore, he is a corresponding member of the National School of Tropical Medicine (NSTM) at the Baylor College of Medicine, Houston, United States.
Affiliations and expertise
Department of Translational Research, N.T.M.S.,
School of Medicine, Universita` di Pisa, Pisa, ItalyRead Trichinella and Trichinellosis on ScienceDirect