Translational Neuroimmunology, Volume 7
Neuroinflammation
- 1st Edition - June 16, 2023
- Latest edition
- Editors: Nima Rezaei, Niloufar Yazdanpanah
- Language: English
Translational NeuroImmunology: Neuroinflammation updates on bench to bedside studies on neurological disorders that have immunological etiologies. The book covers neuroimmu… Read more
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Description
Description
Translational NeuroImmunology: Neuroinflammation updates on bench to bedside studies on neurological disorders that have immunological etiologies. The book covers neuroimmunology and the principles of autoimmune and autoinflammatory neurological disorders, with multiple sclerosis as the main focus. The immunopathology, genetics and epigenetics, microbiome, diagnosis and treatment of multiple sclerosis will be explained in ten chapters. A chapter also examines distinct aspects of pericytes, with final discussions on the neurologic manifestations, diagnostic approaches and treatments of the various neuroimmune disorders and lessons learned from translational research on non-human primates and zebrafish.
All sections are presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research.
Key features
Key features
- Gives an introduction on neuroimmunological diseases, from bench to bedside
- Encourages the development of immunologic approaches to analyze the interaction and specific properties of nervous tissue elements during development and disease
- Focuses on understanding and therapeutically manipulating immunological responses to injury, degeneration and autoimmunity in the central nervous system
- Proves changes in relevant immune and inflammatory reactions at the cellular and molecular level during the development of nervous system diseases
Readership
Readership
Table of contents
Table of contents
1. Introduction on neuroimmunology
2. Neuroimmune interactions: from bench to bedside
3. Neuroimmunology: translational lessons from zebrafish
4. COVID-19-related neuroinflammation may reveal the triggers for healthy longevity
5. Role of neural-immune dysregulation in the periphery in the development of immune dysfunctions
6. Pericytes, a cell type contributing to immune tolerance and autoimmunity
7. Immunity and cognition
8. Neuroimmunology and sleep
9. Impact of systemic inflammation on neuroinflammation
10. Rare autoimmune and autoinflammatory neurologic disorders
11. Epstein-Barr virus and neuroinflammation
12. The potential role of dietary intervention for the treatment of neuroinflammation
13. Immune dysregulation and neurodegenerative diseases
14. Immunological Aspects of Glaucomatous Optic Neuropathy Etiology and Treatments
15. Imaging characteristics of neuroimmunological disorders
16. Contribution of neuroimaging studies to understanding of immunology and inflammation in epilepsy
17. Bedside to bench side translation with the targeting of the BAFF/APRIL axis in neurological autoimmune disorders
18. New insights on Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) as potential therapeutic target for immune mediated neurological disorders
19. Inflammasome Elements in Epilepsy and Seizures
20. Treatment Approaches to Neuroimmunological Diseases: Therapeutic Candidates Affecting Neuroinflammation
Product details
Product details
- Edition: 1
- Latest edition
- Published: June 20, 2023
- Language: English
About the editors
About the editors
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Nima Rezaei
Nima Rezaei, MD, PhD, is Professor of Clinical Immunology and Allergy at Tehran University of Medical Sciences, where he also serves as Associate Dean of International Affairs for the School of Medicine and Director of the Global Academic Program. He is Deputy President of the Research Center for Immunodeficiencies and holds an affiliated research appointment in the Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska Institutet, Sweden. He earned his MD from Tehran University of Medical Sciences and his PhD in Clinical Immunology and Human Genetics from the University of Sheffield, United Kingdom. His research addresses primary immunodeficiencies and translational immunology, with recent work extending into computational and AI-based approaches to immune profiling. He is the founder and President of the Universal Scientific Education and Research Network (USERN) and serves as co-editor of the Springer Nature series Advances in Experimental Medicine and Biology.
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