
Tourette Syndrome, An Issue of Psychiatric Clinics of North America
- 1st Edition, Volume 48-1 - February 1, 2025
- Imprint: Elsevier
- Editor: Joseph F. McGuire
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 3 1 3 6 2 - 2
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 1 3 6 3 - 9
In this issue of Psychiatric Clinics, guest editor Dr. Joseph F. McGuire brings his considerable expertise to the topic of Tourette Syndrome. Over the past decade there has bee… Read more

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Request a sales quoteIn this issue of Psychiatric Clinics, guest editor Dr. Joseph F. McGuire brings his considerable expertise to the topic of Tourette Syndrome. Over the past decade there has been a marked increase in research on the assessment and treatment of persistent tic disorders and Tourette syndrome (collectively referred to as TS) in both children and adults. In this issue, top experts provide a summary of foundational knowledge on this topic, and as well as insights into recent advancements and future directions.
- Contains 13 relevant, practice-oriented topics including neurobiology of Tourette syndrome; neuroimaging and neuro-correlates of Tourette syndrome; evidence-based assessment of Tourette syndrome; functional tics; Tourettic OCD; and more
- Provides in-depth clinical reviews on Tourette syndrome, offering actionable insights for clinical practice
- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews
Psychiatrists
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Foreword
- Preface
- Genetics of Tourette Syndrome
- Key points
- Introduction
- Evidence for the genetic basis of Tourette syndrome
- Genetic findings in Tourette syndrome
- Discussion
- Clinics care points
- The Pathophysiology of Tics: An Anatomic Review
- Key points
- Introduction
- Simplified approach to explaining the pathophysiology of tics
- Overview of cortical-basal ganglia-thalamo-cortical circuits
- Basic cortico-basal ganglia-thalamocortical pathways and their explaination of tics
- Summary
- Clinics care points
- Functional Neuroanatomy of Tics: A Brain Network Perspective
- Key points
- Introduction
- Tic-related brain activity
- Discussion
- Summary
- Clinics care points
- Neurocognitive Functioning in Tourette Syndrome: From Research Findings to Clinical Implementation
- Key points
- Introduction
- Cognitive domains
- Discussion
- Summary
- Clinics care points
- Evidence-Based Assessment of Tourette Syndrome
- Key points
- Introduction
- Screening for Tourette syndrome
- Making a Tourette syndrome diagnosis
- Self-report measures of tic severity
- Child and parent reports of tic severity
- Measures of somatosensory phenomenology in Tourette syndrome
- Measures of other constructs relevant to Tourette syndrome
- Discussion
- Summary
- Clinics care points
- Evidence-Based Behavior Therapy for Tourette Syndrome
- Key points
- Introduction
- Habit reversal training
- Comprehensive behavioral intervention for tics
- Exposure with response prevention
- New directions for behavioral therapies for tics
- Discussion
- Summary
- Clinics care points
- Pharmacotherapy for Tourette Syndrome
- Key points
- Introduction
- General pharmacologic tic treatment guidelines
- First-generation (typical) antipsychotics
- Second-generation (atypical) antipsychotics
- Alpha-2 adrenergic agonists (alpha-agonists)
- Gamma-aminobutyric acid modulating
- Traditional Chinese medicine
- Cannabis/endocannabinoids
- Vesicular monoamine transporter 2 inhibitors
- Ecopipam
- Pharmacology for co-occurring conditions
- Treatment algorithm
- Summary
- Clinics care points
- Mindfulness-Based Interventions for Tourette Syndrome: Current Status and Future Directions
- Key points
- Introduction
- Mindfulness-based intervention for tics
- Review of current evidence
- Discussion
- Summary
- Clinics care points
- Quality of Life in Tourette Syndrome
- Key points
- Introduction
- Measuring quality of life in patients with Tourette syndrome
- Studies of the clinical correlates of quality of life in patients with Tourette syndrome
- Discussion
- Summary
- Clinics care points
- When It’s Not Tics: Functional Tic-Like Behaviors
- Key points
- Introduction
- Clinical presentation
- Etiology
- Epidemiology
- Emerging treatments
- Discussion
- Clinics care points
- Repetitive but Not Interchangeable: Similarities and Differences in the Repetitive Behaviors of Tourette Syndrome, Obsessive-Compulsive Disorder, Tourettic Obsessive-Compulsive Disorder, and Autism Spectrum Disorder
- Key points
- Introduction
- Subtypes of repetitive behaviors
- Tourettic obsessive-compulsive disorder: compulsive complex tics?
- Neuroimaging of Tourette syndrome, obsessive-compulsive disorder, and autism spectrum disorder
- Genetics
- Treatment
- Discussion
- Clinics care points
- Systematic Literature Review on Public Health Impacts of Persistent Tic Disorders: Health Care Needs and Health Care Use
- Key points
- Introduction
- Methods
- Current evidence
- Discussion
- Summary
- Clinics care points
- Disclaimer
- The Role of CBGTC Synaptic Neurotransmission in the Pathophysiology of Tics
- Key points
- Introduction
- Overview of synaptic neurotransmission
- Specific neurotransmitters and evidence for their involvement in tic disorders
- Second messengers and other neuromodulators as potential causes of tics
- Summary
- Clinics care points
- Edition: 1
- Volume: 48-1
- Published: February 1, 2025
- Imprint: Elsevier
- No. of pages: 240
- Language: English
- Hardback ISBN: 9780443313622
- eBook ISBN: 9780443313639
JM
Joseph F. McGuire
Dr. McGuire has over 10 years of research and clinical experience in the assessment and treatment of Tourette syndrome (TS), obsessive compulsive disorder (OCD) and related conditions in children and adults. He has received research support from the National Institute of Mental Health, Tourette Association, and has published over 50 peer-reviewed journal articles related to the assessment and treatment of TS and related conditions.
Affiliations and expertise
Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, USA