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The Toxicology Handbook
- 4th Edition - June 25, 2022
- Authors: Jason Armstrong, Ovidiu Pascu
- Language: English
- Paperback ISBN:9 7 8 - 0 - 7 2 9 5 - 4 4 3 6 - 8
- eBook ISBN:9 7 8 - 0 - 7 2 9 5 - 8 9 3 1 - 4
Now in its fourth edition, the Toxicology Handbook is Australia’s leading reference guide for quick and evidence-informed decision making on treatment of the acutely poisoned pa… Read more
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Request a sales quoteNow in its fourth edition, the Toxicology Handbook is Australia’s leading reference guide for quick and evidence-informed decision making on treatment of the acutely poisoned patient.
The book has been streamlined and fully updated to provide a comprehensive yet concise guide for all medical practitioners and health-care professionals who deal with poisonings. It contains quickly accessible information on poisons, toxins, antidotes, envenomings and antivenoms, and uses a structured and rigorous risk assessment-based approach to guide appropriate treatment decisions.
Written by leading Australian specialists in toxicology and informed by the latest clinical research, this is a must-have addition to all emergency departments and poison information centres.
- Concisely written – helps the student, trainee, and clinician to find information quickly and easily
- A simple, easily remembered and elegant framework (R RSI DEAD) forming the basis of care for all toxicology patients
- Fully revised content, streamlined to be more user-friendly
- Evidence based and up to date – supports appropriate decision making
- Helps resolve common treatment dilemmas, including for digoxin and lithium poisoning, corrosive ingestions and management of envenomings
- Written and edited by experts in the field of toxicology
- An eBook included in all print purchases
- Cover Image
- Title Page
- Copyright
- Table of Contents
- Foreword to 4th Edition
- Preface to 4th Edition
- Editors
- Contributors
- Chapter 1 Approach to the Poisoned Patient
- 1.1 Overview
- 1.2 Resuscitation
- 1.3 Risk Assessment
- 1.4 Supportive Care and Monitoring
- 1.5 Investigations
- 1.6 Gastrointestinal Decontamination
- 1.7 Enhanced Elimination
- 1.8 Antidotes
- 1.9 Disposition
- Chapter 2 Specific Considerations
- 2.1 Coma
- 2.2 Hypotension
- 2.3 Seizures
- 2.4 Approach to Delirium
- 2.5 Serotonin Toxicity
- 2.6 Anticholinergic Toxicity
- 2.7 Cholinergic Toxicity
- 2.8 Neuroleptic Malignant Syndrome
- 2.9 Alcohol Use Disorder
- 2.10 Amphetamine Use Disorder
- 2.11 Opioid Use Disorder
- 2.12 Sedative-Hypnotic Use Disorder
- 2.13 Solvent Abuse
- 2.14 Body Packers and Stuffers
- 2.15 Osmolar Gap
- 2.16 Acid–Base Disorders
- 2.17 The 12-Lead ECG in Toxicology
- 2.18 Approach to Mushroom Poisoning
- 2.19 Approach to Plant Poisoning
- 2.20 Poisoning During Pregnancy and Lactation
- 2.21 Poisoning in Children
- 2.22 Poisoning in the Elderly
- Chapter 3 Specific Toxins
- 3.1 Alcohol: Ethanol
- 3.2 Alcohol: Ethylene Glycol
- 3.3 Alcohol: Isopropanol (isopropyl alcohol)
- 3.4 Alcohol: Methanol (methyl alcohol)
- 3.5 Alcohol: Other Toxic Alcohols
- 3.6 Amisulpride
- 3.7 Amphetamines and Amphetamine-Like Substances
- 3.8 Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin II Receptor Blockers (ARBs)
- 3.9 Anticoagulant Rodenticides
- 3.10 Anticonvulsants: Newer Agents
- 3.11 Antihistamines (non-sedating)
- 3.12 Antihistamines (sedating)
- 3.13 Arsenic
- 3.14 Baclofen
- 3.15 Barbiturates
- 3.16 Benzodiazepines
- 3.17 Benztropine
- 3.18 Beta-Blockers
- 3.19 Bupropion
- 3.20 Button Batteries
- 3.21 Calcium Channel Blockers (CCBs)
- 3.22 Cannabinoids and synthetic cannabinoid receptor agonists (SCRAs)
- 3.23 Carbamazepine
- 3.24 Carbon Monoxide
- 3.25 Chloroquine and Hydroxychloroquine
- 3.26 Chloral Hydrate
- 3.27 Clonidine and other central α2-adrenergic agonists
- 3.28 Clozapine
- 3.29 Cocaine
- 3.30 Colchicine
- 3.31 Corrosives
- 3.32 Cyanide
- 3.33 Digoxin: Acute Overdose
- 3.34 Digoxin: Chronic Poisoning
- 3.35 Diphenoxylate–Atropine
- 3.36 Direct Oral Anticoagulants
- 3.37 Gamma-Hydroxybutyrate (GHB)
- 3.38 Glyphosate
- 3.39 Hydrocarbons
- 3.40 Hydrofluoric Acid
- 3.41 Hydrogen Peroxide
- 3.42 Insulin
- 3.43 Iron
- 3.44 Isoniazid
- 3.45 Lamotrigine
- 3.46 Lead
- 3.47 Lithium: Acute Overdose
- 3.48 Lithium: Chronic Poisoning
- 3.49 Local Anaesthetic Agents
- 3.50 Mercury
- 3.51 Metformin
- 3.52 Methotrexate
- 3.53 Mirtazapine
- 3.54 Monoamine Oxidase Inhibitors (MAOIs)
- 3.55 Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
- 3.56 Olanzapine
- 3.57 Opioids
- 3.58 Organochlorines
- 3.59 Organophosphorus Agents (organophosphates and carbamates)
- 3.60 Paracetamol: Immediate-Release Preparations (Acute Overdose)
- 3.61 Paracetamol: Modified-Release Formulations
- 3.62 Paracetamol: Repeated Supratherapeutic Ingestion
- 3.63 Paraquat
- 3.64 Phenothiazines and Butyrophenones (antipsychotic agents)
- 3.65 Phenytoin
- 3.66 Potassium Chloride
- 3.67 Pregabalin
- 3.68 Quetiapine
- 3.69 Quinine
- 3.70 Risperidone
- 3.71 Salicylates
- 3.72 Selective Serotonin Reuptake Inhibitors (SSRIs)
- 3.73 Strychnine
- 3.74 Sulfonylureas
- 3.75 Theophylline
- 3.76 Thyroxine
- 3.77 Tramadol and Tapentadol
- 3.78 Tricyclic Antidepressants (TCAs)
- 3.79 Valproic Acid (sodium valproate)
- 3.80 Venlafaxine and Desvenlafaxine
- 3.81 Warfarin
- Chapter 4 Antidotes
- 4.1 Atropine
- 4.2 Calcium
- 4.3 Cyproheptadine
- 4.4 Desferrioxamine
- 4.5 Digoxin Immune Fab
- 4.6 Dimercaprol
- 4.7 DMSA (Succimer) and DMPS (Unithiol)
- 4.8 Ethanol
- 4.9 Flumazenil
- 4.10 Folinic Acid
- 4.11 Fomepizole
- 4.12 Glucose
- 4.13 Hydroxocobalamin
- 4.14 Insulin (high-dose)
- 4.15 Intravenous Lipid Emulsion
- 4.16 Methylene Blue
- 4.17 N-Acetylcysteine
- 4.18 Naloxone
- 4.19 Octreotide
- 4.20 Penicillamine
- 4.21 Physostigmine
- 4.22 Pralidoxime
- 4.23 Pyridoxine
- 4.24 Sodium Bicarbonate
- 4.25 Sodium Calcium Edetate
- 4.26 Sodium Thiosulfate
- 4.27 Vitamin K
- Chapter 5 Envenomings
- 5.1 Approach to Snakebite
- 5.2 Black Snake
- 5.3 Brown Snake
- 5.4 Death Adder
- 5.5 Tiger Snake Group
- 5.6 Taipan
- 5.7 Sea snakes
- 5.8 Australian Scorpions
- 5.9 Bluebottle Jellyfish (Physalia species)
- 5.10 Stonefish
- 5.11 Box Jellyfish
- 5.12 Irukandji Syndrome
- 5.13 Blue-Ringed Octopus
- 5.14 Redback Spider
- 5.15 Funnel-Web (Big Black) Spider
- 5.16 White-Tailed Spider
- 5.17 Ticks
- Chapter 6 Antivenoms
- 6.1 Black Snake Antivenom
- 6.2 Brown Snake Antivenom
- 6.3 Death Adder Antivenom
- 6.4 Tiger Snake Antivenom
- 6.5 Taipan Antivenom
- 6.6 Sea Snake Antivenom
- 6.7 Polyvalent Snake Antivenom
- 6.8 Stonefish Antivenom
- 6.9 Box Jellyfish Antivenom
- 6.10 Redback Spider Antivenom
- 6.11 Funnel-Web Spider Antivenom
- 6.12 Allergic Reactions to Antivenom
- Appendices
- Appendix 1: Poisons Information Telephone Numbers
- Appendix 2: Conversion Factors and Therapeutic Ranges for Important Toxins
- Appendix 3: N-Acetylcysteine (NAC) IV Infusion for Paracetamol Poisoning
- Appendix 4: Alcohol Withdrawal Score
- Toxicology Handbook Index
- No. of pages: 560
- Language: English
- Edition: 4
- Published: June 25, 2022
- Imprint: Elsevier
- Paperback ISBN: 9780729544368
- eBook ISBN: 9780729589314
OP
Ovidiu Pascu
Affiliations and expertise
Consultant Emergency Physician and Clinical Toxicologist, Sir Charles Gairdner Hospital, Perth, WA Poisons Information Centre; Clinical Senior Lecturer in Emergency Medicine, University of Western Australia, WA, Australia