
The Sepsis Codex
- 1st Edition - November 30, 2022
- Imprint: Elsevier
- Editors: Marcio Borges, Jorge Hidalgo, Javier Perez-Fernandez
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 8 2 7 1 - 2
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 8 2 8 0 - 4
Offering a global, multidisciplinary perspective on this life-threatening medical emergency, The Sepsis Codex provides a concise yet comprehensive look at a complex topic. Nearly… Read more
Purchase options

Institutional subscription on ScienceDirect
Request a sales quoteOffering a global, multidisciplinary perspective on this life-threatening medical emergency, The Sepsis Codex provides a concise yet comprehensive look at a complex topic. Nearly 20% of global deaths are attributed to sepsis annually, nearly half of which are in children under the age of five, with low-resource settings being disproportionately affected. A “one size fits all” approach is not sufficient to meet individual patients’ needs, instead requiring a therapeutic approach that considers different ages, predisposing factors, genetic traits, and more. This cutting-edge resource brings you up to date with recent medical advances in this challenging area.
Covers pathophysiology, early detection, biomarkers and diagnosis, therapies, controversies, future research, the use of AI, professional organizations and public health in sepsis.
Includes chapters on sepsis in special populations such as in pregnant women, transplanted patients, and children.
Consolidates today's available information on this timely topic into a single, convenient resource.
Infectious Disease
PART I INTRODUCTION
1 Sepsis: Past, Present, and Futured Lessons Learned from COVID-19
2 Sepsis Definitions: A Historical Perspective
3 The Epidemiology of Sepsis
PART II BASIC CONCEPTS
4 Pathophysiology of Sepsis
5 Sepsis and Microcirculation
6 Genetics and Sepsis
PART III DIAGNOSIS AND MONITORING
7 Screening and early detection of sepsis
8 Diagnosis and Monitoring of Sepsis
9 Sepsis: Molecular Diagnostics and Biomarkers
10 Hemodynamic Monitoring: Current Practice and New Perspectives
11 Point of Care Ultrasound in the Management of Sepsis
12 New Approaches and Understanding of Sepsis
13 Sepsis Quality Indicators in the Emergency Department
PART IV TREATMENT
14 Sepsis Treatment: Fluids
15 Vasopressor Therapy in Septic Shock
16 Mechanical Ventilation in Sepsis
17 Extracorporeal Membrane Oxygenation for the Support of Patients with Refractory Septic Shock
18 Antimicrobials in the Management of Sepsis
19 Kidney Support in Sepsis
20 Hematological Support in Sepsis
21 Specific Treatment of Focus Control in Sepsis
22 Sepsis Adjunctive Therapies
23 Glycemic Control and Stress Ulcer Prophylaxis
24 Nutrition in Sepsis
PART V SPECIAL SETTINGS
25 Fever in Intensive Care Units
26 SepsisdIn the Era of Antimicrobial Resistance
27 Factors Underlying Racial and Gender Disparities in Sepsis Management
28 Sepsis in Special Populations
29 Comprehensive Management of Sepsis in Pediatrics
30 Maternal Sepsis
PART VI SPECIAL CONSIDERATIONS
31 Role of Preventive Measures in Sepsis
32 Value of the Protocolization and Sepsis Performance Improvement Program in Early Identification
33 Long-Term Sequelae of Sepsis
PART VII FUTURE OUTLOOK
34 New Diagnostic and Therapeutic Perspectives
35 Artificial Intelligence in Sepsis
INDEX
1 Sepsis: Past, Present, and Futured Lessons Learned from COVID-19
2 Sepsis Definitions: A Historical Perspective
3 The Epidemiology of Sepsis
PART II BASIC CONCEPTS
4 Pathophysiology of Sepsis
5 Sepsis and Microcirculation
6 Genetics and Sepsis
PART III DIAGNOSIS AND MONITORING
7 Screening and early detection of sepsis
8 Diagnosis and Monitoring of Sepsis
9 Sepsis: Molecular Diagnostics and Biomarkers
10 Hemodynamic Monitoring: Current Practice and New Perspectives
11 Point of Care Ultrasound in the Management of Sepsis
12 New Approaches and Understanding of Sepsis
13 Sepsis Quality Indicators in the Emergency Department
PART IV TREATMENT
14 Sepsis Treatment: Fluids
15 Vasopressor Therapy in Septic Shock
16 Mechanical Ventilation in Sepsis
17 Extracorporeal Membrane Oxygenation for the Support of Patients with Refractory Septic Shock
18 Antimicrobials in the Management of Sepsis
19 Kidney Support in Sepsis
20 Hematological Support in Sepsis
21 Specific Treatment of Focus Control in Sepsis
22 Sepsis Adjunctive Therapies
23 Glycemic Control and Stress Ulcer Prophylaxis
24 Nutrition in Sepsis
PART V SPECIAL SETTINGS
25 Fever in Intensive Care Units
26 SepsisdIn the Era of Antimicrobial Resistance
27 Factors Underlying Racial and Gender Disparities in Sepsis Management
28 Sepsis in Special Populations
29 Comprehensive Management of Sepsis in Pediatrics
30 Maternal Sepsis
PART VI SPECIAL CONSIDERATIONS
31 Role of Preventive Measures in Sepsis
32 Value of the Protocolization and Sepsis Performance Improvement Program in Early Identification
33 Long-Term Sequelae of Sepsis
PART VII FUTURE OUTLOOK
34 New Diagnostic and Therapeutic Perspectives
35 Artificial Intelligence in Sepsis
INDEX
- Edition: 1
- Published: November 30, 2022
- Imprint: Elsevier
- Language: English
- Paperback ISBN: 9780323882712
- eBook ISBN: 9780323882804
MB
Marcio Borges
Affiliations and expertise
Associate Professor of Infectious Disease Balearic Islands University; Coordinator, Multidisciplinary Sepsis Unit, Critical Care Medicine, Son Llatzer University Hospital, Palma de Mallorca, SpainJH
Jorge Hidalgo
Dr. Jorge Hidalgo is a Professor of Critical Care and the Head of the Division of Critical Care at Karl Heusner Memorial Hospital in Belize, Central America. He is the President Elect of the World Federation of Societies of Critical Care and Intensive Care Medicine. He has won several awards with the highest recognition and the Director of the very prestigious ACP Review Course hosted by the Paraguay Society of Internal Medicine. Due to his outstanding contribution to the Society of Critical Care Medicine he received the Presidential Citation Award. And Global Safar Award, becoming the First Latin American Intensivist to get this Nomination. He is involved in numerous congresses and a well-recognized international speaker.
Affiliations and expertise
Professor and Head, Division of Critical care, Karl Heusner Memorial Hospital, Belize, Central AmericaJP
Javier Perez-Fernandez
Dr. Javier Perez-Fernandez serves as Medical Director of the Critical Care Services at Baptist Hospital of Miami. He is a Clinical Associate Professor of Medicine at Florida International University, Herbert Wertheim College of Medicine and Professor Pulmonary and Critical Care Medicine at Larkin University, Miami-Dade Florida. He is the Secretary-General of the World Federation of Intensive Care.
Dr. Perez-Fernandez manages a large group of critical care physicians, South Florida Critical Care Services, overseeing the operations of seven ICUs with over 350 beds. He has been a regional and national recognized leader during the COVID-19 pandemic with multiple TV and media appearances and consulting services for several national and international organizations. He has been directly involved in the development of Rapid Response Teams, technology implementation and “open ICU” models. He has lectured worldwide and author of many original publications with the Society of Critical Care Medicine.
Affiliations and expertise
Medical Director, Critical Care Services Baptist Hospital of Miami, Florida, USARead The Sepsis Codex on ScienceDirect