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Elsevier

The Rose and Mackay Textbook of Autoimmune Diseases

  • 7th Edition - July 26, 2024
  • Latest edition
  • Editors: M. Eric Gershwin, George C. Tsokos, Betty Diamond
  • Language: English

**Selected for 2025 Doody’s Core Titles® with "Essential Purchase" designation in Allergy/Clinical Immunology**The Rose-Mackay Textbook of Autoimmune Diseases, Seventh Edit… Read more

Description

**Selected for 2025 Doody’s Core Titles® with "Essential Purchase" designation in Allergy/Clinical Immunology**

The Rose-Mackay Textbook of Autoimmune Diseases, Seventh Edition is a comprehensive reference that emphasizes the "3 P’s" of 21st Century medicine: precision, prediction, and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients.

This new edition continues its success with 75% of the content revised, updated, or completely new. This edition is a valuable resource to clinicians involved in the diagnosis and treatment of autoimmune disease, as well as to scientists who want to follow developments in the field.

Key features

  • Provides new research on autoimmune diseases, their diagnosis, prevention, and therapy
  • Covers a complete range of all common, rare and new autoimmune diseases, including cancer and COVID
  • Extensively revised with 75% new material based on autoimmunity, developments in the different diagnosis and therapies for these autoimmune diseases, and a completely updated description of the different diseases
  • Supplemented with a website that hosts a Podcast per chapter

Readership

Researchers, scientists, clinicians, clinical investigators, pathologists, medical students, and graduate students in the biomedical sciences in immunology, rheumatology, genetics, cell biology and molecular biology, Academic institutions especially those researchers active in immunology/oncology/infectious disease and those teaching immunology for graduate and post-graduate degrees, Basic and clinical scientists working in immunology, rheumatology and autoimmune diseases

Table of contents

Section 1: Immunologic Basis of Autoimmunity

1. Prelude: Historical introduction to autoimmunity and autoimmune disease

2. Structural and Functional Aspects of the Innate and Adaptive Systems of Immunity

3. General Features of Autoimmune Diseases (same title new contributor, new content)

4. Antigen Presentation, Dendritic Cells, and Autoimmunity

5. T cells and their subsets

6. Role of Th1 Th2 Th17 Cells in Autoimmunity

7. Tolerance and Autoimmunity: T Cells

8. Regulatory T Cells

9. B Cells and Autoimmunity

10. Immunological memory T cells

11. Immunological memory B cells

12. Apoptotic Cells as a Source of Autoantigens

13. Effector Mechanisms of Autoimmunity: Antibodies and Immune Complexes

14. Functional Effects of Autoantibodies

15. Cytokine, Chemokines 16. Signaling Pathways in T and B Lymphocytes

17. HLA Genetics and Autoimmunity

18. Non HLA Genetics

19. AIRE related Autoimmunity

20. Immune Deficiencies and Autoimmunity

21. Infections and Autoimmunity

22. Noninfectious Environmental Agents and Autoimmunity

23. Sex, Pregnancy and Autoimmunity

24. Animal Models of Autoimmune Disease

Section 2: Multisystem Diseases

25. Systemic Lupus Erythematosus

26. Systemic Sclerosis, Scleroderma

27. Antiphospholipid Syndrom

28. Sjogren Syndrome

29. Rheumatoid Arthritis

30. Spondyloarthritis and Chronic Idiopathic Arthropathies

31. Myositis

32. Thyroid Disease

33. Type 1 Diabetes

34. Adrenalitis

35. Polyendocrine Syndromes

36. Gastritis and Pernicious Anemia

37. Hypophysitis

38. Hemolytic Anemia

39. Thrombocytopenic Purpura

40. Neutropenia

41. Aplastic Anemia

42. Clotting Disorders

43. Multiple Sclerosis

44. Peripheral Neuropathy

45. Myasthenia Gravis

46. Ocular Disease

47. Inner Ear Disease

48. Celiac Disease

49. Inflammatory Bowel Diseases: Ulcerative Colitis and Crohn’s Disease

50. Chronic Hepatitis

51. Primary Billiary Cirrhosis

52. Primary Sclerosing Cholangitis

53. Pancreatitis

54. Bullous Skin Diseases: Pemphigus and Pemphigoid

55. Non-Bullous Skin Diseases: Alopecia, Vitiligo, Psoriasis and Urticaria

56. Kidney Disease: Goodpasture’s Disease, Lupus Nephritis, ANCA-Associated Glomerulonephritis

57. Orchitis and Male Infertility

58. Oophoritis

59. Rheumatic Heart Disease

60. Myocarditis and Dilated Cardiomyopathy

61. Necrotizing Arteritis and Small Vessel Vasculitis

62. Large and Medium Vessel Vasculitides

63. Autoimmune Disorders of the Lung

64. Paraneoplastic Diseases

65. Antibody-Associated Neurological Diseases

66. Autoinflammatory and other Related Diseases

67. Autoinflammatory diseases and autoimmune responses to tumors

68. COVID

Section 3: Diagnosis, Prevention, and Therapy

69. Autoantibody Assays, Testing, and Standardization

70. Prediction of Autoimmune Disease

71. Emerging Therapies for Autoimmune Diseases

72. Postlude

Review quotes

"...provides comprehensive information on autoimmune diseases, covering the basics to clinical practice. Authored by over 200 experts on the subject, the purpose of this book is to provide in-depth and up-to-date information on the basics and clinical aspects of autoimmune diseases....emphasizes the '3 Ps: Precision, Prediction, and Prevention,' aiming to present this collection as an authoritative resource on autoimmune diseases. The target groups are rheumatologists, allergists, and clinical immunologists, as well as fellows-in-training and scientists interested in autoimmune diseases....This comprehensive collection includes every autoimmune disease and related concept, formatted as two volumes divided into 11 parts and 80 chapters,...[which] contain various colorful visual aids, which are essential teaching tools, especially in the presentation of immune-related topics. The present edition continues the legacy of being a single authoritative resource of information on autoimmune diseases."©Doody's Book Review Service, 2025, Massoud Mahmoudi, DO, PhD (University of California San Francisco)

Product details

  • Edition: 7
  • Latest edition
  • Published: August 5, 2024
  • Language: English

About the editors

MG

M. Eric Gershwin

M. Eric Gershwin, MD, is chief of the division of rheumatology, allergy, and clinical immunology at the University of California at Davis. Gershwin is currently working to further understand the molecular basis of immune regulation in autoimmunity. He also studies the molecular-genetic basis of autoimmune liver disease. Gershwin is interested in the molecular and genetics tools being utilized to study the genes that contribute to a patient's susceptibility to lupus and the cellular and subcellular mechanisms that lead to immune disease.
Affiliations and expertise
Distinguished Professor of Medicine, The Jack and Donald Chia Professor of Medicine and Chief, Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, USA

GT

George C. Tsokos

George C. Tsokos, MD, is a Professor of Medicine at Harvard Medical School and Chief of Rheumatology and Clinical Immunology at Beth Israel Deaconess Medical Center. Dr Tsokos has served as President of the Clinical Immunology Society, on the boards of directors for the American College of Rheumatology and the Lupus Foundation of America, member/chair of multiple federal study sections, and editor/member of the editorial boards for top scientific journals. He has received several awards, including a MERIT from NIH, the Lee C. Howley Sr. Prize, the Evelyn V. Hess, the Distinguished Basic Investigator Award from the American College of Rheumatology, the Lupus Insight Prize from the Lupus Research Alliance, and the Carol Nachman Prize for Rheumatology. He is a Master of the American College of Physicians and the American College of Rheumatology, a member of American Association of Physicians and Fellow of AAAS.

Affiliations and expertise
Professor of Medicine, Harvard Medical School and Chief of Rheumatology and Clinical Immunology, Beth Israel Deaconess Medical Center, USA

BD

Betty Diamond

Dr. Betty Diamond graduated with a BA from Harvard University and an MD from Harvard Medical School. Dr. Diamond has headed the rheumatology divisions at Albert Einstein School of Medicine and at Columbia University Medical Center. She also directed the Medical Scientist Training Program at Albert Einstein School of Medicine for many years. She is currently director of the Institute of Molecular Medicine at The Feinstein Institutes for Medical Research and director of the PhD and MD/PhD programs of the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell. Dr. Diamond is a fellow of the American Association for the Advancement of Science (AAAS) and a member of the National Academy of Medicine and the National Academy of Sciences.

Affiliations and expertise
Institute of Molecular Medicine, Feinstein Institutes for Medical Research, New York, NY, USA

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