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The Practical Guide to Clinical Research and Publication
- 1st Edition - August 3, 2021
- Author: Uzung Yoon
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 5 1 7 - 0
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 4 5 1 8 - 7
The Practical Guide to Clinical Research and Publication provides a comprehensive overview of the key foundations of epidemiology, statistics and epidemiological studies. This b… Read more
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Request a sales quoteThe Practical Guide to Clinical Research and Publication provides a comprehensive overview of the key foundations of epidemiology, statistics and epidemiological studies. This book presents the most important terms and knowledge in the field from a medical point-of-view. Sections contain numerous, clinically-oriented examples and drawings to facilitate understanding and clarify the relation to clinic and practice. The book contains many graphics and key points for easier understanding and is written using bullet points for ease of use and comprehension. It is ideal for physicians and clinical researchers who want to use it as guidance for clinical research or teaching.
- Contains numerous, clinically-oriented examples and drawings
- Provides an explanation of epidemiology and statistics to aid understanding of clinical research
- Written by a physician with extensive knowledge in research
Physicians and clinical researchers can use this book as a guidance for clinical research or teaching. Medical students could use this book for guidance, examinations or it could be used for medical student lectures
- Cover image
- Title page
- Table of Contents
- Copyright
- Preface
- Acknowledgment
- Chapter 1. Introduction
- Abstract
- Chapter outline
- Clinical research in medicine
- Endnote
- Chapter 2. Evidence-based medicine
- Abstract
- Chapter outline
- Evidence-based medicine
- Science-based medicine
- Biomedical literature databases (Table 2.1)
- Endnotes
- Chapter 3. Epidemiology
- Abstract
- Chapter outline
- Definition and classification
- Association and causality
- Epidemiologic measures
- Endnotes
- Chapter 4. Biostatistics
- Abstract
- Chapter outline
- Fundamentals of statistics
- Graphics in statistics
- Data distribution
- Significance value
- Confidence interval (Fig. 4.9)
- Diagnostic testing
- Measure of association
- Endnote
- Chapter 5. Planning a research study
- Abstract
- Chapter outline
- Planning a research study (Fig. 5.1)
- Research question
- Hypothesis
- Study protocol
- Study registration
- Sample size
- Endnotes
- Chapter 6. Study design
- Abstract
- Chapter outline
- Classification of clinical studies (Fig. 6.1)
- Descriptive studies
- Analytical studies
- Literature analytical studies
- Clinical practice guidelines
- HTA reports
- Health economic studies
- Pharmacological studies
- Endnotes
- Chapter 7. Hierarchy of evidence
- Abstract
- Chapter outline
- Hierarchy of evidence
- Recommendation scale according SIGN (Table 7.1)
- Disadvantages
- Recommendation scale according Cox (Table 7.2)
- Randomized controlled trials versus observational studies. Which one is better?
- Endnotes
- Chapter 8. Funding
- Abstract
- Chapter outline
- Funding sources
- Types of fund based on carrier level (Figs. 8.1 and 8.2; Table 8.1)
- Applying for a grant (Fig. 8.3)
- Components of research strategy
- Budget
- Important writing tips
- Chapter 9. Data collection
- Abstract
- Chapter outline
- Data collection
- Questionnaire
- Checklist to review a questionnaire
- Quality criteria
- Quality of life measuring instruments
- Chapter 10. Scaling and coding
- Abstract
- Chapter outline
- Scaling and coding
- Chapter 11. Statistical tests
- Abstract
- Chapter outline
- Statistic software
- Comparison of proportions
- Comparison of mean values
- Regression analysis
- Survival analysis
- Correlation coefficient
- Consistency measurements
- Statistical errors
- Statistical data presentation
- Chapter 12. Random and systematic errors
- Abstract
- Chapter outline
- Random and systematic errors (Fig. 12.1)
- Effect modification/interaction
- Chapter 13. Writing a manuscript and publication (Fig. 13.1)
- Abstract
- Chapter outline
- Purpose of scientific publishing
- Finding the appropriate journal
- Impact factor
- Journal rankings
- Scientific writing
- Journal submission
- Review process
- Revision
- Journal rejection
- Chapter 14. Critical literature review
- Abstract
- Chapter outline
- Not everything is evidence
- Report quality & methodical quality
- Chapter 15. Checklist for quality assessment
- Chapter outline
- Timmer score (Table 15.1)
- Jadad scale
- Consort for abstract—items to include when reporting a randomized trial in a journal or conference abstract (Table 15.3)
- CONSORT statement (Table 15.4)
- CONSORT flowchart (Fig. 15.1)
- STROBE statement (Table 15.5)
- SIGN 50 for systematic review and meta analysis (Table 15.6)
- SIGN 50 for randomized controlled trials (Table 15.7)
- SIGN 50 for cohort study (Table 15.8)
- SIGN 50 for case control study (Table 15.9)
- Index
- No. of pages: 222
- Language: English
- Edition: 1
- Published: August 3, 2021
- Imprint: Academic Press
- Paperback ISBN: 9780128245170
- eBook ISBN: 9780128245187
UY
Uzung Yoon
Dr. Yoon (MD, MPH) graduated from Hannover Medical School in Germany. During that time he conducted 5 years of laboratory and clinical research and graduated with a MD/PHD equivalent degree. Additionally, he finished a 1 year public health master at Berlin School of Public Health. He wrote a book in German” Von der wissenschaftlichen Fragestellung zur Publikation“ published with Elsevier Germany in 2014. Currently he is a faculty member for Anesthesiology at Thomas Jefferson University Hospital in Philadelphia and continues to conduct and lead clinical research.
Affiliations and expertise
Assistant Professor, Director of Anesthesia, Coagulation Laboratory, Thomas Jefferson University Hospital, Philadelphia, USARead The Practical Guide to Clinical Research and Publication on ScienceDirect