
The Origins of Life
From Abiotic Chemistry to the First Cells
- 1st Edition - April 25, 2025
- Imprint: Academic Press
- Authors: Randy O. Wayne, Thomas Owens, Karl Niklas
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 3 3 5 4 4 - 0
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 3 5 4 5 - 7
The Origins of Life: From Abiotic Chemistry to the First Cells is an essential textbook that tackles one of the greatest mysteries in science, how inanimate matter evolved into t… Read more

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Request a sales quoteThe Origins of Life: From Abiotic Chemistry to the First Cells is an essential textbook that tackles one of the greatest mysteries in science, how inanimate matter evolved into the first living things. The book takes an interdisciplinary approach, delving into the basic principles of the earth’s chemistry, the formation of pre-cellular entities, and the acquisition of chemical complexity. It explains the creation of chromosomes, metabolic pathways, and the features of the earliest prokaryotes. Users will find a detailed exposition of the World RNA Hypothesis in an accessible and easy-to-read style which is comprehensible for both science and non-science majors.
This textbook is a critical resource for upper-level undergraduate students in Cellular Biology, specifically those studying or researching evolution, cellular chemistry, and pre-biotic chemistry, as well as non-science majors in courses on the philosophy of science or related topics. It is also useful for professionals in biochemistry, evolutionary biology, and astrobiology who wish to understand the origins of life and first cells. Science communicators could use this interdisciplinary textbook for teaching and dissemination to broader audiences as well.
This textbook is a critical resource for upper-level undergraduate students in Cellular Biology, specifically those studying or researching evolution, cellular chemistry, and pre-biotic chemistry, as well as non-science majors in courses on the philosophy of science or related topics. It is also useful for professionals in biochemistry, evolutionary biology, and astrobiology who wish to understand the origins of life and first cells. Science communicators could use this interdisciplinary textbook for teaching and dissemination to broader audiences as well.
- Functions as a readable and instructive book on the evolution of life
- Offers a deep dive into the first principles of the physical sciences
- Explores, in detail, the emergence of life from inanimate matter
- Presents the RNA World Hypothesis in considerable depth
Students in undergraduate courses on Cellular Biology
- Title of Book
- Cover image
- Title page
- Table of Contents
- Copyright
- Preface
- Introduction
- Chapter 1. Basic Principles and How They Constrain the Path to Life
- Chapter 2. Abiotic Chemistry, Physicochemical Selection, and the First Steps Toward Life
- Chapter 3. Membranes and the Critical Role of Containment
- Chapter 4. “Defeating” Chemical Equilibrium and the Rise of Chemical Complexity
- Chapter 5. Catalysis and Molecular Selection: The RNA World Hypothesis
- The Oparin-Haldane coacervate model
- The Wachtershaüser model
- The Martin-Russell model
- The Lancet-Segrè lipid-world model
- The RNA world hypothesis
- Commonalities
- Chapter 6. From the RNA World to the DNA Genetic Code
- Chapter 7. Controlling Chemistry: Metabolism and Systemic Time
- Chapter 8. Genome Concatenation and Controlled Division: The Final Steps
- Chapter 9. Natural Selection and Major Evolutionary Transitions
- Glossary
- Index
- Edition: 1
- Published: April 25, 2025
- Imprint: Academic Press
- No. of pages: 300
- Language: English
- Paperback ISBN: 9780443335440
- eBook ISBN: 9780443335457
RW
Randy O. Wayne
Randy O. Wayne is a plant cell biologist at Cornell University notable for his work on plant development. In particular, along with his colleague Peter K. Hepler, Wayne established the powerful role of calcium in regulating plant growth; accordingly, their 1985 article, Calcium and plant development, was cited by at least 405 subsequent articles to earn the "Citation Classic" award from Current Contents magazine and has been cited by hundreds more since 1993. He is an authority on how plant cells sense gravity through pressure, on the water permeability of plant membranes, light microscopy, as well as the effects of calcium on plant development. He has published over 50 articles and is the author of another book, Light and Video Microscopy.
Affiliations and expertise
Plant Cell Biologist, Cornell University, USATO
Thomas Owens
Tom Owens is an emeritus professor at Cornell University. Over the course of his career, he taught classes that spanned the range from Introductory Biology through the physiology, biochemistry, and biophysics of plant processes. His research encompassed the physiology and molecular biophysics of photosynthesis
Affiliations and expertise
Cornell University, USAKN
Karl Niklas
Karl Niklas is an emeritus professor at Cornell University. He is the author of five books, and has taught classes ranging from Introductory Biology, Introductory Botany, Evolution, and Biomechanics. His research has focused on the application of engineering principles and physics to understand biology and evolution.
Affiliations and expertise
Cornell University, USA