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The Neuroscience of Depression
Genetics, Cell Biology, Neurology, Behavior, and Diet
- 1st Edition - March 5, 2021
- Editors: Colin R Martin, Lan-Anh Hunter, Vinood Patel, Victor R Preedy, Rajkumar Rajendram
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 1 7 9 3 5 - 2
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 7 9 3 6 - 9
The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet is a comprehensive reference to the aspects, features and effects of depression. This book… Read more
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Request a sales quoteThe Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet is a comprehensive reference to the aspects, features and effects of depression. This book provides readers with the behavior and psychopathological effects of depression, linking anxiety, anger and PSTD to depression. Readers are provided with a detailed outline of the genetic aspects of depression including synaptic genes and the genome-wide association studies (GWAS) of depression, followed by a thorough analysis of the neurological and imaging techniques used to study depression. This book also includes three full sections on the various effects of depression, including diet, nutrition and molecular and cellular effects. The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet is the only resource for researchers and practitioners studying depression.
- Features a section on neurological and imaging, including SPECT Neuroimaging
- Analyzes how diet and nutrition effect depression
- Examines the molecular and cellular effects of depression
- Covers genetics of depression
- Includes more than 250 illustrations and tables
Researchers, graduate students, and clinicians in behavioral neuroscience, cognitive neuroscience, neurobiology, translational neuroscience, and neuropsychology
Part I. Genetic Aspects of Depression 1. Epigenetics in depressionPiotr Czarny, Katarzyna Bialek, Sylwia Ziolkowska, Monika Talarowska, and Tomasz Sliwinski2. Genes, depression and nuclear DNA Xenia Gonda and Peter Petschner3. Gene expression in depression: Molecular aspects of postpartum depression Anna Landsman4. Genetics and epigenetics of the SLC6A4 gene in depressionM. S. Mendonça, Paula M. Mangiavacchi, and Álvaro F.L. Rios5. Molecular basis of tryptophan metabolism disorders associated with depression Paulina Wigner, Piotr Gałecki, and Tomasz Śliwiński6. Metalloproteinases genes and their relationship with depressionMonika Sienkiewicz, Michał Seweryn Karbownik, Mateusz Kowalczyk, Edward Kowalczyk, and Monika Talarowska7. Linking gene regions jointly with environment and depressionArianna M. Gard and Erin B. Ware
Part II. Molecular and cellular effects of depression
8. Linking depression, mRNA translation, and serotonin Emily Arsenault, Aisha Asad Ahmed, Ayeila Daneshmend, Zeynep JihadMohamad, Edna Matta-Camacho, Melissa Nyveld, Fatimeh-Frouh TaghaviAbkuh, Molly Zhang, Nahum Sonenberg, Jean-Claude Lacaille, and Argel Aguilar-Valles9. Changes in cortical gene expression in major depressive disorders: More evidence implicating inflammatory-related pathways in disease etiologyBrian Dean10. FKBP5 gene expression as a biomarker for treatment outcome in depressionMarcus Ising11. Neuroimaging a cytokine storm by transducing IL-1α to hippocampal cornu ammonis: COVID-19 SARS-CoV-2Patricia A. Broderick and Steven L. Cofresi12. Linking interleukin-6 and depressionManivel Rengasamy and Rebecca B. Price13. The role of inflammatory signaling in comorbid depression and epilepsyJana Dimitrova Tchekalarova, Dimitrinka Atanasova, and Nikolai Lazarov14. Brain inflammasomes in depression Stefanie Hoffmann and Cordian Beyer15. Inflammatory factors and depression in substance use disorder María Flores-López, Oscar Porras-Perales, Nerea Requena-Ocaña, Nuria García-Marchena, Pedro Araos, Antonia Serrano, Manuel Jiménez-Navarro, Fernando Rodríguez de Fonseca, and Francisco Javier Pavón16. Linking Huntington disease, brain-derived neurotrophic factor, and depressive-like behaviors Evelini Plácido, Cristine de Paula Nascimento-Castro, Priscilla Gomes Welter, Joana Gil-Mohapel, and Patricia S. Brocardo17. Depression and the NMDA receptor/NO/cGMP pathwayJoão Ronielly Campêlo Araújo and Ana Cristina de Oliveira Monteiro-Moreira18. Translocator protein (18 kDa TSPO) binding in depression Szabolcs Kéri19. Axonal transport proteins: What they are and how they relate to depressive behaviorsArezo Nahavandi and Soraya Mehrabi20. Molecular features of adenylyl cyclase isoforms and cAMP signaling: A link between adenylyl cyclase 7 and depressionGianna Giacoletti, Abdulwhab Shremo Msdi, Ryan Cook, and Tarsis F. Brust 21. Neurobiology of depression: The role of glycogen synthase kinase 3Minal Sonawane, Giuseppe Aceto, Jessica Di Re, Marcello D’Ascenzo, Thomas A Green, and Fernanda Laezza22. Sortilin/neurotensin receptor-3 and its derived peptides in depressionJean Mazella, Marc Borsotto, and Catherine Heurteaux23. Implication of Wnt/beta-catenin signaling and its components in depression and neuropsychiatric disordersAkanksha Mishra, Sonu Singh, and Shubha Shukla24. The prefrontal cortex in depression: Use of proteomicsGábor Juhász, Vanda Tukacs, Dániel Mittli, and Katalin Adrienna KékesiPart III. Neurological and imaging features25. How brain single photon emission computed topography imaging informs the diagnosis and treatment of mood disordersDaniel Amen, Jay Faber, Muneer Ali, Nelson Bennett, Rishi Sood, and Mona Karimpour26. Resting-state functional magnetic resonance imaging (rsfMRI) in bipolar and unipolar depressionKristen K. Ellard, Sofia Uribe, and Christopher J. Funes27. Linking amygdala blood oxygenation-level-dependent (BOLD) activity and frontal EEG in depressionVadim Zotev and Jerzy Bodurka28. The rostromedial tegmental nucleus: Features and links with alcohol and depressionQi Kang Zuo, Wanhong Zuo, Jean Daniel Eloy, and Jiang-Hong Ye29. Human serotonergic neurons, selective serotonin reuptake inhibitor (SSRI) resistance and major depressive disorderKrishna C. Vadodaria, Kelly J. Heard, and Fred H. Gage30. Role of nesfatin-1 in major depressionEce Türkyılmaz Uyar and Efruz Pirdoğan Aydın31. Impact of NGF signaling in neuroplasticity during depression: Insights in neuroplasticity dependent therapeutic approachesMir Hilal Ahmad, M. Moshahid Alam Rizvi, Mahino Fatima, and Amal Chandra Mondal
Part IV. Behaviour and Psychopathological Effects32. Inherited depression and psychological disorders and mental illness by germ cells and their memoryAmani Ahmed and Muaweah Ahmad Alsaleh33. Cognitive function and neurocognitive deficits in depressionMaria Semkovska34. Cognitive and interpersonal contributors to relationship distress and depression: A review of the dyadic partner-schema modelJesse Lee Wilde, Jennifer C.P. Gillies, and David J.A. Dozois35. Cognitive vulnerability to depression in adolescenceRichard T. Liu, Jessica L. Hamilton, and Alexandra H. Bettis36. Determining the cognitive performance in the first episode of depressionMuriel Vicent-Gil and Maria J. Portella37. Body image and depressionPäivi Pylvänäinen (Maria), Anita Forsblom, Joona Muotka, and Katriina Hyvönen38. Sleep, anxiety and depressionLi-Ting Huang and Kelly L. Sullivan39. Depression, anxiety and quality of lifeKeming Gao and Jian Zhang40. Reward processing and depression: Current findings and future directionsDaniel M. Mackin, Brady D. Nelson, and Daniel N. Klein41. Sexual functioning in depressionSandeep Grover and Swapnajeet Sahoo
V. Diet, Nutrition and Botanicals 42. Linking dietary glycemic index and depressionSima Jafarirad and Mehran Rahimlou43. Gut microbiota and depressionAsma Kazemi and Kurosh Djafarian44. Linking dietary methyl donors, maternal separation, and depressionMirian Sanblas, Xabier Bengoetxea, Fermin Milagro, and Maria J. Ramirez45. Convolvulus pluricaulis usage and depressionPriyank Shah and Girdhari Lal Gupta46. Antidepressant activity of Crocus sativus L. and its main constituents: A review Bibi Marjan Razavi, Azar Hosseini, and Hossein Hosseinzadeh47. Mechanisms of action of herbal antidepressantsMahboobeh Ghasemzadeh Rahbardar and Hossein Hosseinzadeh48. Antidepressant-like effects and mechanisms of the herbal formula Xiaochaihutang in depressionKuo Zhang, Jingyu Yang, and Chunfu Wu
Part VI. Resources
49. Recommended resources on the neuroscience of depression: Genetics, cell biology, neurology, behavior, and dietRajkumar Rajendram, Vinood B. Patel, and Victor R. Preedy- No. of pages: 574
- Language: English
- Edition: 1
- Published: March 5, 2021
- Imprint: Academic Press
- Paperback ISBN: 9780128179352
- eBook ISBN: 9780128179369
CR
Colin R Martin
Colin R. Martin RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci is Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director of the Institute of Health and Wellbeing at the University of Suffolk, UK. He is a Chartered Health Psychologist and a Chartered Scientist. He also trained in analytical biochemistry, this aspect reflecting the psychobiological focus of much of his research within mental health. He has published or has in press well over 300 research papers and book chapters. He is a keen book author and editor having written and/or edited more than 50 books. These outputs include the prophetic insight into the treatment of neurological disease, Handbook of Behavior, Food and Nutrition (2011), Nanomedicine and the Nervous System (2012), Oxidative Stress and Dietary Antioxidants in Neurological Disease (2020), Zika Virus Impact, Diagnosis, Control and Models (2021), Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior and Diet (2021), Diagnosis and Treatment of Spinal Cord Injury (2022), The Neurobiology, Physiology, and Psychology of Pain (2022) and The Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging (2023). Professor Martin is particularly interested in all aspects of the relationship between underlying physiological substrates and behavior, particularly in how these relationships manifest in both acute and chronic psychiatric disorder. He has published original research germane to significant mental health disorders including the areas of schizophrenia, anxiety, depression, self-esteem, alcohol and drug dependency, high secure forensic mental health and personality disorder. He has a keen interest in the impact of postviral illness and is actively involved in clinical research post-Covid pandemic and in particular, the impact of Long Covid on psychological, neurological, physiological and social functioning. He is involved in collaborative International research with many European and Non-European countries.
Affiliations and expertise
Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director: Institute for Health and Wellbeing, University of Suffolk, Ipswich, UKLH
Lan-Anh Hunter
Dr Lan-Anh Hunter BSc MBBS DFFP DRCOG MRCGP qualified from Guys, King’s & St. Thomas’ Medical School, London in 2001, where she developed an early interest in psychological medicine. She went on to study culture bound syndromes, whilst reading Medical Anthropology Honours degree at University College London, focusing on the cultural aspects of anorexia nervosa in her thesis. She subsequently worked in Australia and explored the psychological aspects of diabetes and its many complications on the aboriginal population. Prior to becoming a GP Principal, she lectured at Charing Cross Hospital teaching doctors in training, continuing this passion, as a GP trainer in her current role. Much has been written about depression in primary care and hence her call to this area. She specialises in psychological medicine, with training in coaching, narrative based medicine, cognitive behaviour therapy and she continues to see, support, treat and manage clinical depression on an everyday basis as a family GP in her Maidenhead practice.
Affiliations and expertise
Rosemead Surgery, Maidenhead, Berkshire, UKVP
Vinood Patel
Vinood B. Patel, BSc, PhD, FRSC, is currently Professor in Clinical Biochemistry at the University of Westminster. In 2014 Dr Patel was elected as a Fellow to The Royal Society of Chemistry. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King’s College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School, NC, USA studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. Research is being undertaken to study the role of nutrients, antioxidants, phytochemicals, iron, alcohol and fatty acids in the pathophysiology of liver disease. Other areas of interest are identifying new biomarkers that can be used for the diagnosis and prognosis of disease and understanding mitochondrial oxidative stress in neurological disorders and iron dysregulation in diabetes. Dr Patel is a nationally and internationally recognized researcher and has several edited biomedical books related to the use or investigation of active agents or components. These books include The Handbook of Nutrition, Diet, and Epigenetics, Branched Chain Amino Acids in Clinical Nutrition, Cancer: Oxidative Stress and Dietary Antioxidants, Toxicology: Oxidative Stress and Dietary Antioxidants, Molecular Nutrition: Vitamins, The Neuroscience of Pain, Cognitive Behavioural Therapy. He is Editor of the ten-volume series Biomarkers in Disease: Methods, Discoveries and Applications.
Affiliations and expertise
Reader, Clinical Biochemistry, University of Westminster, London, UKVP
Victor R Preedy
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.
Affiliations and expertise
Professor, Department of Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK Visiting Professor, University of Hull, UKRR
Rajkumar Rajendram
Dr Rajkumar Rajendram is a clinician scientist with a focus on internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St. Thomas Medical School, King’s College London in 2001. As an undergraduate he was awarded several prizes, merits and distinctions in pre-clinical and clinical subjects.
Dr Rajendram began his post-graduate medical training in general medicine and intensive care in Oxford. He attained membership of the Royal College of Physicians (MRCP) in 2004 and completed specialist training in acute and general medicine in Oxford in 2010. Dr Rajendram subsequently practiced as a Consultant in Acute General Medicine at the John Radcliffe Hospital, Oxford.
Dr Rajendram also trained in anaesthesia and intensive care in London and was awarded a fellowship of the Royal College of Anaesthetists (FRCA) in 2009. He completed advanced training in regional anaesthesia and intensive care. He was awarded a fellowship of the Faculty of Intensive Care Medicine (FFICM) in 2013 and obtained the European diploma of intensive care medicine (EDIC) in 2014. He then moved to the Royal Free London Hospitals as a Consultant in Intensive Care, Anaesthesia and Peri-operative Medicine. He has been a fellow of the Royal College of Physicians of Edinburgh (FRCP Edin) and the Royal College of Physicians of London (FRCP Lond) since 2017 and 2019 respectively. He is currently a Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia.
Dr Rajendram’s focus on improving outcomes from Coronavirus Disease 2019 (COVID-19) has involved research on point of care ultrasound and phenotypes of COVID-19. Dr Rajendram also recognises that nutritional support is a fundamental aspect of medical care. This is particularly important for patients with COVID-19. As a clinician scientist he has therefore devoted significant time and effort into nutritional science research and education. He is an affiliated member of the Nutritional Sciences Research Division of King’s College London and has published over 400 textbook chapters, review articles, peer-reviewed papers and abstracts.
Affiliations and expertise
Consultant in Internal Medicine, King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi ArabiaRead The Neuroscience of Depression on ScienceDirect