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The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, wh… Read more
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Immediately download your ebook while waiting for your print delivery. No promo code needed.
The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives.
This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe.
Part I. Immune Medicated Cardiac Injury, Accelerated Atherosclerosis and the Study of Cardiac Involvements in Systemic Diseases
Chapter 1. Pathophysiology of Autoimmunity and Immune-Mediated Mechanisms in Cardiovascular Diseases
Chapter 2. Organ-Specific Autoimmune Myocardial Diseases: From Pathogenesis to Diagnosis and Management
Chapter 3. Autoantibodies Directed Against G-Protein-Coupled Receptors in Cardiovascular Diseases: Basics and Diagnostics
Chapter 4. Immune-Mediated Accelerated Atherosclerosis
Chapter 5. A Study of Cardiac Function, Atherosclerosis, and Arrhythmogenicity
Part II. Cardiac Manifestations of Inflammatory Arthritis
Chapter 6. Rheumatoid Arthritis
Chapter 7. Juvenile Idiopathic Arthritis
Chapter 8. Spondyloarthritides: Ankylosing Spondylitis, Psoriatic Arthritis, and Reactive Arthritis
Chapter 9. Polymyalgia Rheumatica
Part III. Cardiac Involvement in Autoimmune and Connective Tissue Diseases
Chapter 10. Systemic Lupus Erythematosus
Chapter 11. Neonatal Lupus
Chapter 12. Sjögren’s Syndrome
Chapter 13. Systemic Sclerosis
Chapter 14. Dermatomyositis and Polymyositis
Part IV. Cardiac Manifestations Crystal-Induced Arthritis
Chapter 15. Gout
Part V. Cardiac Manifestations of Large Vessel Vasculitides
Chapter 16. Giant Cell Arteritis
Chapter 17. Takayasu’s Arteritis
Part VI. Cardiac Manifestations of Medium Vessel Vasculitides
Chapter 18. Polyarteritis Nodosa
Chapter 19. Kawasaki Disease
Part VII. Cardiac Manifestations of Small Vessel Vasculitides
Chapter 20. ANCA-Associated Vasculitis: Microscopic Polyangiitis, Eosinophilic Granulomatosis With Polyangiitis (Churg–Strauss Syndrome) and Granulomatosis With Polyangiitis (Wegener’s Granulomatosis)
Part VIII. Cardiac Manifestations of Variable Vessel Vasculitides
Chapter 21. Behçet’s Disease
Part IX. Post-Infectious Autoimmune Cardiac Diseases
Chapter 22. Rheumatic Fever and Rheumatic Heart Disease
Chapter 23. Chagas Cardiomyopathy
Part X. Autoinflammation
Chapter 24. Familial Mediterranean Fever
Part XI. Therapeutic Approaches: Mechanisms of Action and Cardiac Effects
Chapter 25. Desirable and Adverse Effects of Antiinflammatory Agents on the Heart
Chapter 26. The Effects of Immunosuppressive and Cytotoxic Drugs on the Heart
Chapter 27. Autoantibody-Directed Therapy in Cardiovascular Diseases
Chapter 28. Cardiac Immunomodulation
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