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The HDL Handbook
Biological Functions and Clinical Implications
1st Edition - August 12, 2010
Editor: Tsugikazu Komoda
Hardback ISBN:9780123821713
9 7 8 - 0 - 1 2 - 3 8 2 1 7 1 - 3
eBook ISBN:9780123821720
9 7 8 - 0 - 1 2 - 3 8 2 1 7 2 - 0
The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians… Read more
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The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol.
Comprehensive coverage of basic science, genetics, epidemiology and treatment
Reputable content on latest advances in HDL cholesterol research
Inclusive, worldwide content with country specific information
In depth discussion of potential targets to modify HDL
The primary audience for this work is researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular biology, molecular medicine, and pathophysiology of cardiovascular diseases; researchers and clinicians working with an aging population; corporate researchers; postdocs; medical students and graduate students.
The secondary audience is allied health professionals, nurses, and researchers and clinicians studying nutrition.
Introduction
Role of phospholipid transfer protein (PLTP) in HDL remodelling and Atherosclerosis
The role of CETP in HDL metabolism
The physiological role of CETP in HDL molecule metabolism
HDL and reverse cholesterol transport: Physiological modulation
Serum Paraoxonase PON1 and its interactions with HDL: Relationship between PON1 and oxidative stress
Paraoxonase PON1 and its interaction with HDL: Molecular structures of PON1 and HDL
Apoliopoprotein A-I mutations
The Scavenger Receptor Class B Type I: An HDL Receptor Involved in Lipid Transport and HDL Dependent Signaling
HDL and its mimetic peptides: Novel therapeutic strategies for the treatment of inflammatory vascular disease
Sterol efflux by ABCA1 and ABCG1
Possible roles of oxidized HDL: Structural change of HDL particle by oxidative modification and its contribution to vascular diseases
Pre¿1-HDL: Conversion to and from spherical ¿-migrating HDL in human plasma
Determination of circulating native and denaturated HDL concentrations and its clinical implications
No. of pages: 296
Language: English
Edition: 1
Published: August 12, 2010
Imprint: Academic Press
Hardback ISBN: 9780123821713
eBook ISBN: 9780123821720
TK
Tsugikazu Komoda
Dr. Komoda is a visiting professor at Toho University School of Medicine in Japan. He has extensive expertise with research in alkaline phosphatase, amylase, and oxidized HDL. He co-operated the intestinal alkaline phosphatase at Washington University School of Medicine in St. Louis, Missouri. He is the recipient of the Kodama Memorial Award from Japanese Society of Electrophoresis.
Affiliations and expertise
Visiting Professor, Toho University School of Medicine, Japan