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The Common Marmoset in Captivity and Biomedical Research

  • 1st Edition - November 19, 2018
  • Latest edition
  • Editors: Robert P. Marini, Lynn M. Wachtman, Suzette D. Tardif, Keith Mansfield, James G. Fox
  • Language: English

The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the exist… Read more

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Description

The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the American
College of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset
(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such as
macaques, but without the attendant physical and zoonotic risks.

Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. The
marmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primate
model to study a number of poorly understood disorders, like autism.

Key features

  • Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications
  • Includes contributions from renowned and international authors and editors
  • Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series

Readership

Vivarium professionals maintaining marmoset colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using them to gain critical insights into human physiology and disease

Table of contents

Section I: BIOLOGY AND MANAGEMENT

1. Taxonomy and Natural History

2. The Anatomy of the Common Marmoset

3. Neuroanatomy of the Marmoset

4. Marmoset Nutrition and Dietary Husbandry

5. Husbandry and Housing of Common Marmosets

6. Normal Clinical and Biological Parameters of the Common Marmoset (Callithrix jacchus)

7. Behavior and Behavioral Management

8. Reproduction, Growth, and Development

9. Regulatory Considerations

Section II: DISEASES AND CLINICAL APPLICATIONS

10. Physical Examination, Diagnosis, and Common Clinical Procedures

11. Anesthesia and Common Surgical Procedures

12. Diseases of the Urogenital System

13. Diseases of the Gastrointestinal System

14. Bone, Muscle, and Skeletal Disease

15. Viral Diseases of Common Marmosets

16. Bacterial Diseases

17. Parasitic Diseases

18. Neoplastic Diseases

Section III: RESEARCH AND APPLICATIONS

19. The Genome of the Common Marmoset

20. Creating Genetically Modified Marmosets

21. Marmosets in Aging Research

22. The Marmoset Monkey as a Model for Visual Neuroscience

23. Marmosets in Neurologic Disease Research: Parkinson’s Disease

24. Experimental Autoimmune Encephalomyelitis in the Marmoset as a Translational Model for Multiple Sclerosis

25. Marmosets in Auditory Research

26. The Marmoset as a Model in Behavioral Neuroscience and Psychiatric Research

27. The Use of the Marmoset in Toxicity Testing and Nonclinical Safety Assessment Studies

28. Experimental Infections of the Common Marmoset (Callithrix jacchus)

29. Insights Gained from Marmoset Endocrine Research

Review quotes

"This book is the result of an international effort, and it provides an in-depth Review of the common marmoset including numerous excellent illustrations, particularly in the anatomy and neuroanatomy sections. ...This book will be an invaluable reference for colony managers, veterinarians, behaviorists, and investigators involved in the care, propagation, and research application of common marmosets. Moreover, the value of this book extends beyond the biomedical research community because its contents cover the broad topic of the natural history of common marmosets, which will be of interest to the zoological and conservation communities as well."—Journal of the American Veterinary Medical Association

Product details

  • Edition: 1
  • Latest edition
  • Published: November 19, 2018
  • Language: English

About the editors

RM

Robert P. Marini

Robert P. Marini, DVM, DACLAM, Assistant Director, is a member of MIT’s Division of Comparative Medicine’s clinical staff and is Chief of the Division’s clinical surgical facilities. Dr. Marini is responsible for coordinating and supervising all major survival surgery in non-rodent mammalian species.
Affiliations and expertise
MIT Division of Comparative Medicine, Cambridge, MA USA

LW

Lynn M. Wachtman

Harvard Medical School, Boston MA USA
Affiliations and expertise
Lynn M. Wachtman, DVM, MPH, is a clinical veterinarian and instructor in Pathology at Harvard Medical School.

ST

Suzette D. Tardif

Suzette D. Tardif, Ph.D., is the Associate Director of Research at the Southwest National Primate Research Center. She is an adjunct faculty of The Barshop Institute. The Tardif laboratory's activities center on the development of the marmoset monkey as a disease model. Dr. Tardiff is a past-President of the American Society of Primatologists.
Affiliations and expertise
Barshop Institute for Longevity & Aging Studies, San Antonio, TX USA

KM

Keith Mansfield

Keith Mansfield is Associate Director for Resource and Collaborative Affairs and Chair, Division of Primate Resources, New England National Primate Research Center, Harvard Medical School, Harvard University, Southborough, US. His research focuses on primarily on the recognition of spontaneously occurring infectious diseases of nonhuman primates and their development into novel animal models to investigate disease pathogenesis.
Affiliations and expertise
Novartis Institutes for Biomedical Research,Cambridge, MA, U.S.A.

JF

James G. Fox

Prof. James G. Fox obtained his Doctor of Veterinary Medicine at Colorado State University, Fort Collins, and, as an NIH postdoctoral fellow, received a Master of Science in Medical Microbiology at Stanford University. Dr. Fox is an adjunct professor at Tufts University School of Veterinary Medicine. He is a diplomate and a past president of the American College of Laboratory Animal Medicine, as well as a past president of the Massachusetts Society for Medical Research and the American Association of Veterinary Medical Colleges. Additionally, he has served as past chairman of the AAALAC Council and the NCCR/NIH Comparative Medicine Study Section. He is also an elected fellow of the Infectious Disease Society of America and the American Gastroenterological Association. He was recruited to MIT and created the Division of Comparative Medicine, which he directed from 1974 until 2021. As a faculty member in the MIT Department of Biological Engineering, Professor Fox received numerous scientific awards and was elected to the National Academy of Medicine in 2004. Dr. Fox has been the principal investigator of an NIH postdoctoral training grant for veterinarians for 30 years and has trained 90 veterinarians for careers in biomedical research. The NIH has continuously funded him to study infectious diseases of the gastrointestinal tract, where he has studied the gastrointestinal microbiome and how it interfaces with and influences the host’s immune response to gastrointestinal pathogens, particularly oncogenic Helicobacter species. He has authored over 600 papers, 84 chapters, holds 4 patents and has authored or edited 18 comparative medicine texts.

Affiliations and expertise
Division of Comparative Medicine, Department of Biological Engineering, MIT, Cambridge, MA, USA

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