Textbook of Pathology, 2nd Editon
- 2nd Edition - September 18, 2024
- Imprint: Elsevier India
- Authors: Rajeswari Kathiah, Gayathri Devi T, Indhu Kannan
- Language: English
- Paperback ISBN:9 7 8 - 8 1 - 3 1 2 - 6 9 8 3 - 1
- eBook ISBN:9 7 8 - 8 1 - 3 1 2 - 6 9 8 5 - 5
The second edition of this book is meticulously crafted to align with the CBME curriculum, addressing every facet of the new guidelines comprehensively. The content is not only… Read more
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Request a sales quoteThe second edition of this book is meticulously crafted to align with the CBME curriculum, addressing every facet of the new guidelines comprehensively. The content is not only updated and advanced but also clinically correlated and tailored to meet the learners’ needs. This book represents endeavour to render Pathology not only simple and engaging but also deeply fascinating and inspires learners to delve further into the subject and discover its profound implications beyond the classroom.
New to This Edition
Each chapter opens with a list of competencies, guiding learners through essential topics and “must-read” concepts.
Self-assessment have been introduced at the end of each chapter enable learners to evaluate their understanding, incorporating Multiple Choice Questions, problem-based and case-based learning scenarios.
Additional content on noncore topics enhances the learning experience with self-directed study options.
Mind maps at the end of chapters offer a unique strategy to help learners retain and recall information effectively.
Histopathological illustrations of tissues used in disease analysis at the end of book bolster understanding and aid in memorizing complex concepts.
Key Features
Adopts a conceptual approach to both core and non-core competencies.
Each chapter begins with relevant anatomy and histology, refreshing learners’ foundational knowledge.
Clinical correlations are seamlessly integrated within the content.
One of the critical aspects of pathology, “Morphology,” is emphasized throughout to engage and captivate learners.
A high number of images, charts and illustrations comprehend aids in memorizing complex concepts
Online Features at www.medenact
Complimentary access to full e-book.
Lecture PPTs designed to simplify teaching and enhance the learning experience during lectures, featuring high-quality images.
New to This Edition
Each chapter opens with a list of competencies, guiding learners through essential topics and “must-read” concepts.
Self-assessment have been introduced at the end of each chapter enable learners to evaluate their understanding, incorporating Multiple Choice Questions, problem-based and case-based learning scenarios.
Additional content on noncore topics enhances the learning experience with self-directed study options.
Mind maps at the end of chapters offer a unique strategy to help learners retain and recall information effectively.
Histopathological illustrations of tissues used in disease analysis at the end of book bolster understanding and aid in memorizing complex concepts.
Key Features
Adopts a conceptual approach to both core and non-core competencies.
Each chapter begins with relevant anatomy and histology, refreshing learners’ foundational knowledge.
Clinical correlations are seamlessly integrated within the content.
One of the critical aspects of pathology, “Morphology,” is emphasized throughout to engage and captivate learners.
A high number of images, charts and illustrations comprehend aids in memorizing complex concepts
Online Features at www.medenact
Complimentary access to full e-book.
Lecture PPTs designed to simplify teaching and enhance the learning experience during lectures, featuring high-quality images.
- Textbook of Pathology
- Cover image
- Title page
- Table of Contents
- Copyright
- Preface to the second edition
- Preface to the first edition
- Acknowledgements
- Contributors
- Reviewers for the second edition
- Competency map: Pathology
- List of Illustrations
- List of Tables
- 1. Cell as a unit of health and disease
- Introduction
- Normal cell structure
- The genome
- Fundamental housekeeping mechanisms of cells
- Growth factors and receptors
- Signalling pathways (Fig. 1.16)
- Role of extracellular matrix
- Cell cycle
- Stem cells
- 2. Cell injury and adaptations
- Overview of cellular responses to stress
- Cellular adaptations PA 2.6
- Overview of cell injury and cell death
- Causes of cell injury PA 2.1
- Mechanisms of cell injury PA 2.2
- Morphological changes in cell injury (Table 2.3) PA 2.2
- Ischaemia–reperfusion injury
- Apoptosis PA 2.4, PA 2.7
- Autolysis PA 2.4
- Autophagy
- Intracellular accumulations PA 2.3
- Pathological calcification PA 2.5
- Cellular ageing PA 2.7
- 3. Inflammation, healing and repair
- Overview of inflammation
- Acute inflammation PA 4.1
- Chronic inflammation PA 4.3
- Systemic effects of inflammation (Fig. 3.27)
- Healing and repair PA 5.1
- Mind maps
- 4. Haemodynamic disorders
- Introduction
- Hyperaemia and congestion PA 6.2
- Haemorrhage PA 6.2
- Oedema and effusions PA 6.1
- Haemostasis PA 6.4
- Thrombosis PA 6.4
- Embolism PA 6.5
- Infarction PA 6.6
- Shock PA 6.3
- Mind maps
- 5. Genetic disorders
- Introduction
- Mendelian disorders PA 11.1
- Autosomal disorders with defects in structural proteins
- Autosomal disorders with defective receptor proteins
- Autosomal disorders with enzyme defects PA 11.3
- Non-mendelian disorders
- Complex multigenic disorders/multifactorial disorders
- Chromosomal disorders
- Molecular genetic diagnosis
- Mind maps
- 6. Immune disorders
- The immune system
- The normal immune response PA 9.1
- Hypersensitivity reactions PA 9.2
- Autoimmune disorders PA 9.4, PA 9.5, PA 9.7
- Immunodeficiency disorders
- Acquired immunodeficiency syndrome PA 9.6
- Transplant rejection reactions PA 9.3
- Amyloidosis PA 3.1
- Mind maps
- 7. Neoplasia
- Overview PA 7.1
- Epidemiology and aetiology of cancer
- Molecular basis of malignancies PA 7.2
- Carcinogenic agents and carcinogenesis PA 7.3
- Clinical presentation of tumours
- Paraneoplastic syndromes (Table 7.20) PA 7.4
- Laboratory diagnosis of cancer
- Molecular profiling of tumours: Precision oncology
- Mind maps
- 8. Infectious diseases
- Introduction
- Common bacterial infections
- Common viral infections
- Common fungal infections
- Parasitic infections
- Emerging infectious diseases
- Special techniques for diagnosis of infectious diseases
- 9. Environmental and nutritional disorders
- Introduction
- Environmental effects on global disease burden
- Environmental pollution
- Effects of tobacco PA 12.1
- Effects of alcohol PA 12.1
- Injury by physical agents
- Nutritional diseases
- Mind map
- 10. Disorders of infancy and childhood
- Introduction
- Congenital anomalies
- Diseases associated with prematurity
- Fetal hydrops
- Inborn errors of metabolism
- Other genetic disorders
- Sudden infant death syndrome
- Tumours and tumour-like lesions of infancy and childhood PA 11.2
- Mind maps
- 11. Basic diagnostic cytology and clinical pathology
- I. Basic diagnostic cytology
- Introduction
- Role of diagnostic cytology PA 8.1
- Advantages and disadvantages of cytology
- Staining methods in cytology
- Types of diagnostic cytology
- II. Clinical pathology
- Urine analysis PA 23.1
- Examination of body fluids PA 23.2
- Organ function tests PA 23.3
- Semen analysis
- 12. Advanced diagnostic techniques
- Introduction
- Immunohistochemistry
- Immunofluorescence
- Frozen section
- Flow cytometry
- Electron microscopy
- Polarizing microscopy
- Fluorescence in situ hybridization
- Electrophoresis
- Blotting techniques
- Polymerase chain reaction
- Next-generation sequencing
- Multiplex ligation-dependent probe amplification
- Linkage analysis
- Tissue microarray
- Digital pathology
- 13. Blood vessels
- Overview of vascular system
- Vessel wall response to injury
- Hypertensive vascular disease
- Arteriosclerosis PA 27.1
- Atherosclerosis PA 27.1
- Aneurysms and dissection PA 27.2
- Vasculitis
- Vascular tumours
- 14. The heart
- Introduction
- Overview of cardiac structure and physiology
- Overview of cardiac pathophysiology
- Heart failure PA 27.3
- Congenital heart diseases
- Ischaemic heart disease PA 27.5
- Arrhythmias
- Sudden cardiac death
- Hypertensive heart disease
- Syphilitic heart disease PA 27.10
- Diseases of the valves
- Cardiomyopathies PA 27.9
- Pericardial diseases PA 27.7
- Cardiac tumours
- 15. Red cell disorders
- Introduction and basic haematology
- Anaemias PA 13.3
- Polycythaemia
- Mind maps
- 16. Disorders of white blood cells, lymph nodes, spleen and thymus
- Introduction
- I. White blood cells and lymph nodes
- II. Spleen
- III. Thymus
- Mind maps
- 17. Bleeding disorders
- Review of haemostasis PA 21.1
- Bleeding disorders
- Disorders due to vessel wall abnormality PA 21.2
- Disorders due to platelet abnormality
- Disseminated intravascular coagulation PA 21.4
- Vitamin K deficiency PA 21.5
- Platelet versus clotting disorders (Table 17.8) PA 21.3
- Approach to a patient with bleeding disorder (Flowchart 17.5)
- Mind maps
- 18. Transfusion medicine
- Introduction to transfusion medicine
- Blood group systems (Table 18.1) PA 22.1
- Pretransfusion compatibility tests PA 22.2
- Blood components (cellular and plasma) and plasma derivatives (fractions) PA 22.4
- Transfusion reactions PA 22.6
- Transfusion-transmissible infections PA 22.5
- Autologous blood donation PA 22.7
- Mind maps
- 19. The lungs
- Introduction
- Atelectasis
- Pulmonary oedema
- Acute lung injury and acute respiratory distress syndrome
- Obstructive and restrictive lung diseases (Table 19.3)
- Obstructive pulmonary diseases PA 26.3
- Restrictive lung diseases
- Diseases of pulmonary blood vessels
- Tuberculosis PA 26.4
- Pulmonary infections
- Tumours PA 26.6
- Lung transplantation
- Pleura
- 20. Head and neck
- I. Diseases of the oral cavity
- II. Diseases of the upper airways
- III. Diseases of the neck
- IV. Diseases of the salivary glands
- 21. The gastrointestinal tract
- Anatomy and histology
- Congenital anomalies
- Oesophagus
- Stomach
- Small intestine and colon
- Mind maps
- 22. Liver and gallbladder
- Introduction
- Anatomy, histology and functions of the liver
- Mechanisms of injury and repair
- Liver failure PA 25.2
- Hepatitis PA 25.3
- Fatty liver disease
- Alcoholic liver disease PA 25.4
- Inherited liver diseases
- Cholestatic diseases
- Autoimmune cholangiopathies
- Nodules and tumours of the liver
- Gallbladder
- 23. The pancreas
- Anatomy and histology of pancreas
- Congenital anomalies
- Pancreatitis
- Non-neoplastic cysts of the pancreas
- Pancreatic neoplasms
- 24. The kidney
- Introduction and basics
- Clinical manifestations of renal disease
- Renal failure PA 28.2
- Glomerular diseases PA 28.5
- Tubular and interstitial diseases
- Vascular diseases PA 28.11
- Cystic diseases of the kidney PA 28.12
- Obstructive uropathy (urinary tract obstruction) PA 28.13
- Neoplasms of the kidney PA 28.14
- Mind maps
- 25. The lower urinary tract and male genital system
- I. Lower urinary tract
- Development, anatomy and histology
- Congenital anomalies of the lower urinary tract
- Ureters
- Urinary bladder
- Urethra
- Diseases of the ureters
- Diseases of the urinary bladder
- Diseases of the urethra
- II. Male genital system
- Development, anatomy and histology of the male genital system
- Congenital anomalies
- Diseases of the penis
- Diseases of the testis and epididymis
- Prostate
- 26. The female genital tract
- Introduction
- Vulva
- Vagina
- Cervix
- Endometrium and body of the uterus
- Fallopian tubes
- Ovaries
- Gestational trophoblastic diseases PA 30.5
- Mind maps
- 27. The breast
- Introduction
- Clinical presentation of breast diseases
- Developmental disorders
- Inflammatory lesions
- Benign epithelial lesions PA 31.1
- Stromal tumours PA 31.1
- Gynaecomastia PA 31.4
- Carcinoma of the breast PA 31.2
- Male breast cancer
- Other malignant tumours of the breast
- Tubular carcinoma (Fig. 27.30)
- Cribriform carcinoma
- Mucinous carcinoma (Fig. 27.31)
- Medullary carcinoma (Fig. 27.32)
- Invasive papillary carcinoma
- Invasive micropapillary carcinoma (Fig. 27.33)
- Apocrine carcinoma
- Neuroendocrine tumour
- Secretory carcinoma
- Metaplastic carcinoma
- Inflammatory carcinoma (Fig. 27.34)
- Invasive lobular carcinoma
- 28. The endocrine system
- Introduction
- I. The thyroid gland
- II. The parathyroid gland
- III. The endocrine pancreas
- IV. The adrenal gland
- 29. The skin
- Introduction
- Inflammatory dermatoses
- Blistering (bullous) diseases
- Infections
- Disorders of melanocytes
- Benign epithelial tumours
- Premalignant epidermal tumours
- Malignant epidermal tumours
- Adnexal tumours
- Dermal tumours
- Tumours of migrants to skin
- 30. Bones, joints, soft-tissue tumours, skeletal muscle and peripheral nervous system
- I. Bones
- Structure and functions of bone
- Developmental disorders of bone and cartilage
- Metabolic disorders of bone
- Osteomyelitis PA 33.1
- Tumours and tumour-like lesions PA 33.2
- II. Joints
- Osteoarthritis
- Rheumatoid arthritis PA 33.5
- Seronegative spondyloarthropathies
- Infectious arthritis
- Crystal-induced arthritis
- III. Soft tissues
- Tumours PA 33.3
- Tumours of adipose tissue
- Fibrous tumours
- Smooth muscle tumours
- Tumours of uncertain origin
- Undifferentiated pleomorphic sarcoma
- IV. Skeletal muscles
- Inherited diseases
- Skeletal muscle tumours
- Tumours
- Rhabdomyoma
- Rhabdomyosarcoma (RMS)
- V. Peripheral nerve sheath tumours
- Tumours
- Schwannoma
- Neurofibroma
- Mind Maps
- 31. Central nervous system and eye
- Anatomy and histology
- Reaction of cells of central nervous system to injury
- Cerebrovascular disease
- Infections
- Mechanism of injury
- Prion diseases
- Demyelinating diseases
- Neurodegenerative diseases
- Tumours of the brain PA 35.2
- Eye
- Appendix: Histopathology, cytopathology and haematology diagrams
- Index
- Edition: 2
- Published: September 18, 2024
- Imprint: Elsevier India
- Language: English
- Paperback ISBN: 9788131269831
- eBook ISBN: 9788131269855