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Textbook of Medical Virology
- 1st Edition - June 28, 2014
- Editors: Erik Lycke, Erling Norrby
- Language: English
- Paperback ISBN:9 7 8 - 1 - 4 8 3 1 - 7 6 1 3 - 0
- eBook ISBN:9 7 8 - 1 - 4 8 3 1 - 9 1 9 4 - 2
Textbook of Medical Virology presents a critical review of general principles in the field of medical virology. It discusses the description and molecular structures of virus. It… Read more
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Request a sales quoteTextbook of Medical Virology presents a critical review of general principles in the field of medical virology. It discusses the description and molecular structures of virus. It addresses the morphology and classifications of viruses. It also demonstrates the principal aspects of virus particle structure. Some of the topics covered in the book are the symmetrical arrangements of viruses; introduction to different families of animal viruses; biochemistry of virus particles; the immunological properties and biological activities of viral gene products; description of enzymatic activities of viruses; and haemagglutination, cell fusion, and haemolysis of viruses. The description and characteristics of viral antigens are covered. The identification and propagation of viruses in tissue and cell cultures are discussed. An in-depth analysis of the principles of virus replication is provided. A study of the morphogenesis of virions is also presented. A chapter is devoted to virus-induced changes of cell structures and functions. The book can provide useful information to virologists, microbiologists, students, and researchers.
1 Viruses - A Unique Kind of Infectious Agent
2 The Morphology of Virus Particles. Classification of Viruses
Infectious Nucleic Acid
Principal Aspects of Virus Particle Structure
Live or Dead Materia?
Structural Proteins - Symmetry Arrangements
The Virus Envelope
Classification of Viruses
Introduction to Different Families of Animal Viruses
3 The Biochemistry of Virus Particles
Virus-DNA
Virus-RNA
Virus Proteins
Additional Components in Virions
4 Viral Gene Products; Their Immunological Properties and Biological Activities
Viral Antigens
Haemagglutination
Cell Fusion and Haemolysis
Enzymatic Activities of Viral Gene Products
5 Cultivation of Viruses
Identification and Propagation of Viruses in Tissue and Cell Cultures
Identification and Propagation of Viruses in Embryonated Hen's Eggs
Identification and Cultivation of Viruses in Experimental Animals
6 General Views on Virus Replication
Morphological Methods for Analysis of Virus Replication
Molecular Methods for Characterization of Virus Replication
Quantitative Determination of Virus Infectivity
Quantitative Determination of Other Biological Properties of Viral Products
The Different Phases of Virus Replication
7 Attachment of Viruses to Cell Receptors and Penetration of Viruses Into Cells
Virus and Receptors
Penetration
8 Replication, Transcription and Translation of RNA Viruses
Classes of RNA Viruses
Reoviruses
Picornaviruses
Togaviruses
Rhabdoviruses and Paramyxoviruses
Orthomyxoviruses
Retroviruses
9 Replication, Transcription and Translation of DNA Viruses
Parvoviruses
Papovaviruses
Adenoviruses
Herpesviruses
Poxviruses
10 The Morphogenesis of Virions
The Maturation and Release of Non-Enveloped Viruses
The Morphogenesis of Enveloped Viruses
11 Virus-Induced Changes of Cell Structures and Functions
Cytopathic Changes
Inclusions in Virus-Infected Cells
The Effect of Integration of Viral Antigens in Cellular Membranes
Effects of Viruses on Functions of Highly Specialized Cells
Chromosomal Changes
Virus-Induced Cell Transformation
Interferon
12 Virus Genetics
Mutations
Recombination
Phenotypic Mixing and Complementation
13 General Aspects of Pathogenesis of Virus Infections
Modes of Transmission of Virus Diseases
The Importance of Cellular and Viral Receptor Functions
The Spread of Virus Infections within The Body
The Importance of Barrier Systems in Limiting the Spread of the Infection
Influence of Immune Reactions On The Pathogenesis
Influence of Constitution, Age, Sex and Genetic Background
14 Pathogenesis of Acute Virus Infections
Respiratory Infections
Infections of Visceral Organs
Infections of the Skin and Mucous Membranes
Infections of the Nervous System
15 The Pathogenesis of Congenital Infections
Different Ways by Which a Virus May Cause Fetal Damage
Spread of Virus in Congenital Infections
Direct Effects of Fetal Infections
Indirect Fetal-Damaging Effects in Connection with Infections of Pregnant Women
16 The Pathogenesis of Persistent Infections
Chronic Subclinical Infections with Immune Pathological Reactions
Latent Infections
Slow Virus Infections Caused by Conventional Viruses
17 Slow Infections Caused by Non-Immunogenic Infectious Agents
Different Forms of Infectious Encephalopathy
Biological and Physical-Chemical Properties of Atypical Infectious Agents
How do Atypical Infectious Agents Spread?
18 Viruses and Tumors
Tumor Viruses in Animals
Human Tumor Viruses
Human Tumor Virus Candidates
19 Mechanisms of Defense Against Virus Infections
Non-Specific Immunity
Humoral Immunity
Cell-Mediated Immunity
Immunopathological Effects of Virus Infections
Virus Infections in Connection with Malignant Diseases and Immune Suppression
Immunological Defense Against Congenital Virus Infections
20 Laboratory Techniques for Diagnosis of Virus Infections
Isolation of Viruses
Direct Identification of Virus or Viral Antigens in Samples from Patients
Analysis of Antibody Response In Patients
Evaluation of Laboratory Results
21 The Epidemiology of Virus Diseases
Methods of Surveillance of the Epidemiological Occurrence of Infectious Diseases
The Dissemination Mechanisms of Virus Infections
Epidemiological Patterns of Virus Infections
Examples of the Epidemiology of Some Virus Diseases
22 Inactivation of Viral Infectivity and Disinfection
23 Immune Prophylaxis
Passive Immunization
Active Immunization
24 Antiviral Drugs
Mechanisms of Action of Antiviral Drugs
Antiviral Drugs Used for Clinical Chemotherapy
Antiviral Drugs with a Potential Clinical Usefulness
Interferon
25 Picornaviruses
Properties of Picornaviruses
Enteroviruses
Rhinoviruses
26 Togaviruses
Alphaviruses
Flaviviruses
Rubellavirus (Rubivirus)
27 Orthomyxoviruses (Influenza Viruses)
Properties of the Virus
Clinical Features
Pathogenesis
Epidemiology
Laboratory Diagnosis
Prophylaxis
28 Paramyxoviruses
Parainfluenza Virus
Mumps Virus
Measles Virus
Respiratory Syncytial (RS) Virus
29 Adenoviruses
Properties of the Virus
Clinical Features
Epidemiology
Prophylaxis
30 Hepatitis Viruses
Properties of the Virus
Clinical Features
Pathogenesis
Immunity
Laboratory Diagnosis
Epidemiology
Prophylaxis
31 Herpesviruses
Properties of the Virus
Latency and Transformation
Herpes Simplex Virus (HSV) Infections
Varicella Zoster Virus (VZV) Infections
Cytomegalovirus (CMV) Infections
Epstein-Barr Virus (EBV) Infections
32 Poxviruses
Classification
Properties of the Virus
Variola (Smallpox)
Smallpox Vaccine (Vaccinia Virus)
The WHO Smallpox Eradication Program
Clinical Features of Variola
Laboratory Diagnosis
Other Medically Important Poxviruses
33 Other Viruses
Reoviruses
Retroviruses
Bunyaviruses
Arenaviruses
Coronaviruses
Rhabdoviruses (Rabies Virus)
Marburg/Ebola Virus
Parvoviruses
Papovaviruses
34 Viral Syndromes
Respiratory Tract Infections
Infections of the Pharynx
Infections with Exanthemas
Hepatitis
Gastrointestinal Infections
Urogenital Infections
Infections of the Nervous System
Infections of the Sensory Organs
Neonatal Infections
Appendix. Chlamydia
Microbiology of Chlamydiae
Chlamydia Psittaci Infections
Chlamydia Trachomatis Infections
Laboratory Diagnosis
Susceptibility of Chlamydiae to Antibiotics
Index
- No. of pages: 384
- Language: English
- Edition: 1
- Published: June 28, 2014
- Imprint: Butterworth-Heinemann
- Paperback ISBN: 9781483176130
- eBook ISBN: 9781483191942
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