Targeted Cancer Imaging
Design and Synthesis of Nanoplatforms based on Tumor Biology
- 1st Edition - November 24, 2021
- Authors: Mehdi Azizi, Hadi Kokabi, Hassan Dianat-Moghadam, Mohammad Mehrmohammadi
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 5 1 3 - 2
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 4 5 1 4 - 9
Targeted Cancer Imaging: Design and Synthesis of Nanoplatforms based on Tumour Biology reviews and categorizes imaging and targeting approaches according to cancer type, highlight… Read more
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Request a sales quoteTargeted Cancer Imaging: Design and Synthesis of Nanoplatforms based on Tumour Biology reviews and categorizes imaging and targeting approaches according to cancer type, highlighting new and safe approaches that involve membrane-coated nanoparticles, tumor cell-derived extracellular vesicles, circulating tumor cells, cell-free DNAs, and cancer stem cells, all with the goal of pointing the way to developing precise targeting and multifunctional nanotechnology-based imaging probes in the future. This book is highly multidisciplinary, bridging the knowledge gap between tumor biology, nanotechnology, and diagnostic imaging, and thus making it suitable for researchers ranging from oncology to bioengineering.
Although considerable efforts have been conducted to diagnose, improve and treat cancer in the past few decades, existing therapeutic options are insufficient, as mortality and morbidity rates remain high. One of the best hopes for substantial improvement lies in early detection. Recent advances in nanotechnology are expected to increase our current understanding of tumor biology, allowing nanomaterials to be used for targeting and imaging both in vitro and in vivo experimental models.
- Gives understanding of cancer biology that is appropriate for students and researchers in engineering and nanotechnology
- Demonstrates cancer targeting strategies of multifunctional nanotechnology-based imaging probes
- Shows how to design, synthesize and apply cancer imaging nanostructures
Researchers and students in diagnostic imaging, nanomedicine technology, biotechnology, biomedical engineering, cancer biology, molecular biology, epigenetics, oncology
- Cover image
- Title page
- Table of Contents
- Copyright
- Preface
- Chapter 1. Introduction to cancer biology
- 1. Tumor biology
- Chapter 2. Nanotechnology for cancer theranostics
- 1. Nanoscience and nanotechnology
- Chapter 3. Passive targeting
- 1. Enhanced permeability and retention effect
- 2. Tumor microenvironment
- 3. Direct local delivery
- 4. Nanostructure delivery system for cancer with passive targeting
- Chapter 4. Tumor-specific imaging probes in preclinical applications and clinical trials
- 1. Active targeting
- 2. General approach to active targeting
- 3. Tumor microenvironment targeting
- 4. Endothelial cell surface factors targeting
- 5. Cancer cell surface marker targeting
- 6. Cancer-specific ligand targeting
- 7. Tumor-specific imaging probes in clinical trials
- Chapter 5. Challenges and future directions
- 1. Challenges of targeted delivery
- 2. The nanoparticle journey
- 3. Removing barriers from the nanoparticle journey
- 4. Identifying the ideal nanoparticle design
- 5. Computational techniques to process nano/bio interaction data
- Index
- No. of pages: 216
- Language: English
- Edition: 1
- Published: November 24, 2021
- Imprint: Academic Press
- Paperback ISBN: 9780128245132
- eBook ISBN: 9780128245149
MA
Mehdi Azizi
HK
Hadi Kokabi
HD
Hassan Dianat-Moghadam
MM