Swaiman's Pediatric Neurology

Principles and Practice

7th Edition - February 12, 2025
Imprint: Elsevier
Editors: Stephen Ashwal, Phillip L. Pearl
Language: English
Hardback ISBN:
9 7 8 - 0 - 4 4 3 - 1 0 9 4 4 - 7
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 1 1 1 0 6 - 8

**Selected for 2025 Doody’s Core Titles® in Pediatrics and with "Essential Purchase" designation in Neurology**For fifty years, experienced clinicians and physicians in training… Read more

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**Selected for 2025 Doody’s Core Titles® in Pediatrics and with "Essential Purchase" designation in Neurology**

For fifty years, experienced clinicians and physicians in training have relied on Swaiman’s cornerstone text as their #1 source for authoritative guidance in pediatric neurology. Swaiman's Pediatric Neurology: Principles and Practice, 7th Edition, continues this tradition of excellence under the expert editorial direction of Drs. Stephen Ashwal and Phillip L. Pearl, along with a team of key leaders in the field who serve as associate and section editors in their areas of expertise. Thorough revisions—including new chapters, new videos, new editors, and expanded content—bring you up to date with this dynamic field.

PART I: Clinical Evaluation

1. General Aspects of the Patient’s Neurologic History

2. Neurologic Examination of the Older Child

3. Neurologic Examination of Young Children (Ages 1–5 Years)

4. Neurologic Examination of Infants (Ages 0–1 Year)

5. Motor Signs

6. Vision Loss

7. Hearing Impairment

8. Vertigo

9. Taste and Smell

10. Neuropsychological Assessment

PART II: Care of the Child With Neurologic Disorders

11. Counseling Children With Neurologic Disorders and Their Families

12. Pediatric Neurorehabilitation Medicine

13. Pediatric Palliative Care, Pain, and Symptom Management

14. Practical Bioethics in Child Neurology

15. Transitional Care for Children With Neurologic Disorders

16. Practice Guidelines in Pediatric Neurology

17. Measurement of Health Outcomes in Pediatric Neurologic Disorders

18. Computer Resources, Artificial Intelligence, and Telemedicine

19. Education and Training of Child Neurologists and Workforce Issues

PART III: Neurodiagnostic Testing

20. Cerebrospinal Fluid Examination

21. Pediatric Neuroimaging

22. Pediatric Neurophysiologic Evaluation

PART IV: Global Child Neurology

23. Regional and Global Implications for Children’s Brain Health

24. Implementing Child Neurology Care in Resource-Limited Settings

25. Adaptation and Implementation of Guidelines at the Local Level

PART V: Neonatal Neurology

26. Neonatal Neuro-Intensive Care

27. Provoked Neonatal Seizures and Neonatal Onset Epilepsy

28. Hypoxic-Ischemic Brain Injury in the Term Newborn

29. Cerebrovascular Disorders in the Newborn

30. Neonatal Nervous System Trauma

31. Injury to the Developing Preterm Brain: Intraventricular Hemorrhage and White Matter Injury

32. Perinatal Metabolic Encephalopathies

PART VI: Environment and Brain Development

33. The Neural Exposome and Environmental Neuroscience

34. Adverse Childhood Experiences

35. The Neurological Impact of Prenatal Substance Exposure

36. Environmental Pollutants

37. Malnutrition, Nutrition, and Dietary Toxins

38. Poisoning and Drug-Induced Neurologic Diseases

PART VII: Congenital Structural Defects

39. Introduction to Human Brain Malformations

40. Disorders of Neural Tube Development

41. Disorders of Forebrain Development

42. Disorders of Cerebellar and Brainstem Development

43. Microcephaly and Megalencephaly: Disorders of Brain Size

44. Malformations of Cortical Development

45. Hydrocephalus, Cysts, and Cystic Malformations

46. Congenital Anomalies of the Skull

47. Prenatal Diagnosis of Structural Brain Anomalies

PART VIII: Neurogenetics

48. Neurogenetics in the Genome Era

49. Genetic Counseling in the Genomic Era

50. Chromosomes and Chromosomal Abnormalities

51. Single-Gene Abnormalities

52. Neurocutaneous Disorders

53. Emerging Gene-Based Pathways: Channelopathies (Epilepsy and Beyond)

54. Emerging Gene-Based Pathways: mTORopathies

55. Emerging Gene-Based Pathways: RASopathies

56. Emerging Gene-Based Pathways: Chromatin Remodeling Disorders

57. The Neuronal Ceroid Lipofuscinoses

PART IX: Metabolic Disorders

58. Approach to the Patient With a Metabolic Disorder

59. Aminoacidemias and Organic Acidemias

60. Urea Cycle Disorders

61. Diseases Associated With Primary Abnormalities in Carbohydrate Metabolism

62. Disorders of Glycosylation

63. Lysosomal Storage Diseases

64. Mitochondrial Diseases

65. Peroxisomal Disorders

66. Neurotransmitter-Related Disorders

67. Disorders of Vitamin Metabolism

PART X: Neurodevelopmental Disorders

68. Neurodevelopmental Disabilities: Conceptual Framework

69. Intellectual Developmental Disorder and Global Developmental Delay

70. Regressive and Degenerative Genetic Neurological Disorders

71. Developmental Encephalopathies

72. Developmental Language Disorders

73. Nonverbal Learning Disorders

74. Dyslexia

75. Attention-Deficit/Hyperactivity Disorder

76. Autism Spectrum Disorder

77. Cerebral Palsy

78. Developmental Coordination Disorder

79. Treatment of Neurodevelopmental Disorders

80. Neuropsychopharmacology

PART XI: Epilepsy

81. Overview of Seizures and Epilepsy in Children

82. Principles of Management and Outcome

83. Pathophysiology of Seizures and Epilepsy

84. Epilepsy Genetics

85. Febrile Seizures

86. Generalized Seizures

87. Focal and Multifocal Seizures

88. Myoclonic Seizures

89. Infantile Epileptic Spasms Syndrome

90. Status Epilepticus

91. Electroclinical Syndromes: Neonatal Onset

92. Electroclinical Syndromes: Infantile Onset

93. Electroclinical Syndromes: Childhood Onset

94. Electroclinical Syndromes: Adolescent Onset

95. Focal Structural Epilepsy

96. Acquired Epilepsies: Trauma, Stroke, and Tumors

97. Inherited Metabolic Epilepsies

98. Antiseizure Medication Therapy in Children

99. Epilepsy Surgery in the Pediatric Population

100. Neuromodulation in Epilepsy

101. Ketogenic Diets

102. Behavioral, Cognitive, and Social Implications of Childhood Epilepsy

103. Mortality in Children With Epilepsy

PART XII: Nonepileptiform Paroxysmal Disorders

104. Headache in Children and Adolescents

105. Breath-Holding Spells and Reflex Anoxic Seizures

106. Psychogenic Nonepileptic Seizures and Psychiatric Disorders

107. Functional Neurological Symptom Disorder in Children and Adolescents

108. Syncope and Postural Orthostatic Tachycardia Syndrome

109. Brief Resolved Unexplained Events, Apparent Life-Threatening Events, and Sudden Infant Death Syndrome

PART XIII: Disorders of Sleep

110. Restless Legs Syndrome and Periodic Limb Movement Disorder in Children and Adolescents

111. Nocturnal Paroxysmal Disorders

112. Disorders of Excessive Sleepiness

PART XIV: Disorders of Balance and Movement

113. The Cerebellum and the Hereditary Ataxias

114. Movement Disorders: An Overview

115. Paroxysmal Dyskinesias

116. Movement Disorders of Infancy

117. Drug-Induced Movement Disorders in Children

118. Tics and Tourette Syndrome

PART XV: White Matter Disorders

119. Genetic and Metabolic Disorders of the White Matter

120. Acquired Disorders Affecting the White Matter

PART XVI: Brain Injury and Disorders of Consciousness

121. Impairment of Consciousness and Coma

122. Traumatic Brain Injury in Children

123. Abusive Head Trauma

124. Hypoxic-Ischemic Encephalopathy in Infants and Older Children

125. Disorders of Intracranial Pressure

126. Spinal Cord Injury

127. Determination of Brain Death/Death by Neurologic Criteria in Infants and Children

PART XVII: Cerebrovascular Disease in Children

128. Arterial Ischemic Stroke in Infants and Children

129. Sinovenous Thrombosis

130. Vascular Malformations, Intracerebral Hemorrhage, and Subarachnoid Hemorrhage in Infants and Children

131. Cerebral Arteriopathies

132. Coagulation Disorders and Cerebrovascular Disease in Children

PART XVIII: Infections of the Nervous System

133. Bacterial Infections of the Nervous System

134. Viral Infections of the Nervous System

135. Fungal, Rickettsial, and Parasitic Diseases of the Nervous System

136. Neurologic Complications of Immunization

PART XIX: Immune-Mediated Disorders of the Nervous System

137. Diagnosis and Management of Pediatric Neuroimmunological Disorders

138. Autoimmune Encephalitis

139. Autoimmune-Associated Epilepsies

140. Sydenham Chorea, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcus, and Pediatric Acute Neuropsychiatric Syndrome

141. Immune-Mediated Cerebellar Disorders

142. Neurorheumatology

PART XX: Pediatric Neuro-Oncology

143. Pediatric Neuro-Oncology: An Overview

144. Medulloblastoma

145. Other Embryonal and Pineal Malignancies of the Central Nervous System

146. Ependymoma

147. Pediatric-Type Diffuse High-Grade Glioma

148. Pediatric Low-Grade Glioma

149. Diffuse Intrinsic Pontine Glioma and Diffuse Midline Glioma

150. Atypical Teratoid/Rhabdoid Tumors

151. Central Nervous System Germ Cell Tumors

152. Craniopharyngiomas, Meningiomas, and Schwannomas

153. Pediatric Intradural Spinal Cord Tumors

154. Systemic Cancers and Central Nervous System Involvement

155. Treatment-Related Neurologic Sequelae of Pediatric Central Nervous System Tumors

PART XXI: Neuromuscular Disorders

156. Muscle and Nerve Development in Health and Disease

157. Diagnostic Testing in Children With Suspected Neuromuscular Disorders

158. Clinical Assessment of Pediatric Neuromuscular Disorders

159. The Floppy Infant

160. Classic Proximal Spinal Muscular Atrophy

161. Other Motor Neuron Diseases of Childhood

162. Genetic Peripheral Neuropathies

163. Acquired Peripheral Neuropathies

164. Inflammatory Neuropathies

165. Congenital Myasthenic Syndromes

166. Acquired Disorders of the Neuromuscular Junction

167. Duchenne and Becker Muscular Dystrophy

168. Congenital, Limb-Girdle, and Other Muscular Dystrophies

169. Congenital Myopathies

170. Metabolic Myopathies

171. Inflammatory Myopathies

172. Channelopathies: Myotonic Disorders and Periodic Paralysis

173. Multidisciplinary Management of Children With Neuromuscular Conditions

PART XXII: Systemic and Autonomic Nervous System Diseases

174. Endocrine Disorders of the Hypothalamus and Pituitary in Childhood and Adolescence

175. Disorders of the Autonomic Nervous System: Autonomic Dysfunction in Pediatric Practice

176. Disorders of Micturition and Defecation

177. Neurologic Disorders in Children With Heart Disease

178. Neurologic Disorders Associated With Renal Diseases

179. Neurologic Manifestations and Disorders Associated With Gastrointestinal Diseases

Index

Stephen Ashwal

Stephen Ashwal, MD, is Distinguished Professor and former Chief of the Division of Child Neurology in the Department of Pediatrics at Loma Linda University School of Medicine. He is a graduate of New York University School of Medicine (1966-1970) and completed his residency training programs in Pediatrics (Bellevue Hospital, 1970-1973) and in Child Neurology (University of Minnesota, 1973-1976). His research activities have focused on critical care issues in child neurology related to brain death, the vegetative and minimally conscious states, bacterial meningitis, and near drowning; the role of nitric oxide in focal cerebral ischemia; development of animal models of neonatal stroke and the use of proton spectroscopy for outcome prediction after acute CNS injuries. Dr. Ashwal has been a member of the Child Neurology Society since 1975 and served as chair of the Scientific Selection, Ethics, Archives and Practice Committee, Councilor from the West, Secretary-Treasurer of the Society, and President (2001-2003). He edited The Founders of Child Neurology, published on behalf of the Society in 1990, which is a history of the field of child neurology and its major contributors. He served as co-chair (representing the CNS) on the Multi-Society Task Force on the Persistent Vegetative State. He has been active in the development of practice guidelines related to child neurology and served as a member of the Guidelines Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology that is responsible for development of guidelines dealing with issues related to the evaluation of children with autism, cerebral palsy, developmental delay, headaches and status epilepticus. With Dr. Kenneth Swaiman and other co-editors, he has served as co-editor of one of the main textbooks in the field of child neurology, Swaiman's Pediatric Neurology: Principles & Practice.

Affiliations and expertise

Distinguished Professor of Pediatrics, Former Chief of the Division of Child Neurology and Pediatrics, Loma Linda University School of Medicine, Loma Linda, California, USA

Phillip L. Pearl

Phillip L. Pearl, MD, is Director of Epilepsy and Clinical Neurophysiology and William G. Lennox Chair in the Department of Neurology at Boston Children’s Hospital and Professor of Neurology at Harvard Medical School. Dr. Pearl, originally from Baltimore, attended Johns Hopkins University, Peabody Conservatory of Music, and University of Maryland School of Medicine. He took his residency at Baylor College of Medicine in Houston and fellowship at Boston Children’s Hospital. Dr. Pearl has published over 210 manuscripts and over 100 chapters and reviews, and he has authored or edited five books in the field of child neurology, two of which have been translated into Chinese and Japanese. He is also on the faculty of the Music and Health Institute of the Berklee College of Music in Boston. His major research interest is inherited metabolic epilepsies. Dr. Pearl is Past President of the Professors of Child Neurology and former President of the Child Neurology Society.

Affiliations and expertise

Director of Epilepsy and Clinical Neurophysiology, William G. Lennox Chair and Professor of Neurology, Harvard Medical School, Boston, Massachusetts, USA

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