Genome Editing and Nanotechnology-Based Treatment for Breast Cancers comprehensively covers an introduction to breast cancer, describes the histological and molecular subtypes, gives insight into early detection, provides imaging techniques, and explores the possible treatments.Through 9 sections, it further investigates the factors enhancing the metastasis of breast cancer while also covering the cutting-edge technology of genome editing and nanotechnology for treatment. All these findings offer basic knowledge for the application of genome editing tools in treating breast cancer, which is a key element for producing customized drugs.This book is a valuable resource for researchers and graduate students in cancer research and bioinformatics; oncologists, and all those who wish to broaden their knowledge in the field.
Pediatric Deep Brain Stimulation explores the significance and diverse treatment options using DBS for childhood disorders. The text is structured into four key sections, the first of which provides an extensive overview of a pediatric DBS program, including essential aspects like imaging techniques, potential complications, and ethical considerations. This initial section lays the foundation for understanding the transformative impact of DBS on young patients' lives. The subsequent sections delve into specific applications of DBS. The second section focuses on treating various movement disorders such as dystonia and non-dystonic movement disorders. The third section highlights neuromodulation techniques for managing childhood epilepsy.Finally, the book addresses the use of DBS in treating other pediatric neurodevelopmental disorders. Edited by leading pediatric neurosurgeons, this resource stands as the definitive guide to pediatric brain stimulation, offering invaluable insights for clinicians and researchers alike.
Insights into Migraine Treatments: Towards Personalized Medicine provides knowledge to facilitate the choice of optimal treatment for each patient in the context of migraine care. It presents the numerous therapies to treat migraines, and the methods by which they function. Further, this book discusses the challenges of determining which option is best for a particular patient. It offers key information on efficacy, safety, and biomarkers of patient responses to currently available therapies, thereby providing a resource to help healthcare professionals choose treatments tailored to individual patients. Researchers and clinicians alike will benefit from its solution-driven perspective.Insights into Migraine Treatments: Towards Personalized Medicine discusses topics ranging from pathophysiology of migraines to acute treatments, pharmacological and non-pharmacological preventive treatments, neuroimaging and neurophysiology, all with a view toward meeting the unique needs of each migraine patient.
The Analytical Chemistry of Cannabis, Second Edition provides analytical chemistry methods that address the latest issues surrounding cannabis-based products. Since the first edition was published in 2015, the cannabis industry and their portfolio of recreational and medicinal products has continued to grow and evolve rapidly. The plethora of marketed strains of cannabis and cannabinoid-containing products, combined with the lack of industry standards and labelling requirements, adds to the general perception of poor-quality control and limited product oversight.The methods described in this leading-edge volume help to support the manufacturing, labelling, and distribution of safe and consistent products with known chemical content and demonstrated performance characteristics. The book treats analytical chemistry within the context of the diverse issues surrounding medicinal and recreational cannabis in a manner designed to foster understanding and rational perspective in non-scientist stakeholders as well as scientists who are concerned with bringing a necessary degree of order to a field now characterized by confusion and contradiction. The second edition will provide an update to the basic information regarding chemistry and pharmacology of cannabis and cannabinoids and will further illustrate how analytical chemistry and scientific methods can address, inform, and eventually resolve the variety of challenges faced by industry, consumers, regulators, and researchers are currently experiencing.The Analytical Chemistry of Cannabis, Second Edition is written for a broad spectrum of analytical chemists, pharmacologists, medical doctors, clinical trials specialists, public health officials, international food and drug monitoring agencies, forensics specialists, law enforcement officers. It will also be invaluable to advanced undergraduate and graduate level courses in pharmacy, pharmacology, experimental therapeutics, analytical chemistry, and forensics.
During the last years, there is an increase of field knowledge on a number of comorbidities and extra-articular manifestations (EAMs) associated with inflammatory arthritis. Many adults suffering from inflammatory arthritis also have other chronic conditions, so early detection is key to a patient’s quality of life and survivability outcomes. Comorbidities and Extra-articular Manifestations in Inflammatory Arthritis, the 18th volume in Elsevier’s Handbook for Systemic Autoimmune Diseases series, provides a comprehensive review of the latest research on various comorbidities and EAMs associated with inflammatory arthritis.The book chapters review comorbidities and extra-articular manifestations in early and late disease stages, mechanisms involved in comorbidities development, as well as the impact of new treatment strategies specific to inflammatory arthritis and cardiovascular disease, metabolic syndrome, metabolic bone, infection, neoplasia, respiratory, gastrointestinal, kidney, mental health disease, and neurological disease. This book serves as an ideal reference for researchers and clinicians focused on inflammatory arthritis and related diseases.
Sustainable Solutions for Food Waste: From Recovery to Resource Efficiency explores the magnitude, causes, and environmental impacts of food waste. This book offers practical strategies and innovative technologies for reducing food waste and transforming it into valuable resources. With contributions from leading experts in the field, the book offers a unique perspective on the utilization of food waste in various industries, including grape and winery, fruit juice, olive oil, tea and coffee, dairy, and tropical fruits.Organized into four sections, it comprehensively covers the issue of food waste and sustainability. Section 1 provides an overview of the problem of food waste and the importance of reducing it sustainably, Section 2 focuses on the utilization of waste generated by specific industries, including grape and winery, fruit juice, olive and olive oil, tea and coffee, brewery, dairy, and citrus, Section 3 explores the utilization of waste generated by plant-based industries, including tropical fruit, vegetable, soy, tuberous plant, rice, and hard-shell fruit, and section 4 discusses advanced applications of food waste and resource efficiency.
Applications in Microwave Processing: Expanding the Scope beyond Cooking, Benefits and Risks provides a comprehensive guide on the principles and recent interest in microwave technology, along with its cross-disciplinary applications. Divided into two sections, the first one discusses the foundation of the principle, emerging applications, and recent interest in microwave technology. The second section explores the cross-discipline applications of microwave technology in different fields, which include bioactive extraction, clinical thermo-therapy, polymer processing, catalytic pyrolysis, thermal sterilization, biopharmaceuticals, wastewater treatment, drying process, mineral processing, and in biological process.Overall, this title discusses the drawback of microwave assisted technology, scalability concerns and outlook. Edited by a team of experts in the field, this book is a great asset for all researchers, Industrial expert, Biotechnologist and all interested in optimal management and usage of microwaves.
Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes, Second Edition offers new discoveries in clinical settings, cellular, molecular, genetic, and epigenetic mechanisms which have led to novel understanding of the key role of endothelium in both cardiovascular and non-cardiovascular diseases. The innovations it presents have implications for both pathophysiological concepts and clinical decisions. Among other topics, cardiovascular and pulmonary medicine, immunity and inflammation, genetics and epigenetics, heart failure, renal disease, familial hypercholesterolemia, diabetes, and hypertension are discussed at length.With 20 new chapters covering everything from endothelium transition to connective tissue disorders, this second edition is sure to be indispensable to anyone wishing to learn the importance of endothelium to every facet of health.
Interaction of Food Macromolecules: The Matrix of Future Foods provides a detailed understanding on why biological macromolecules, i.e., proteins, lipids, and carbohydrates with ligands interactions are essential to understanding biology at the molecular level. The book aims to create a multidisciplinary forum of discussion on the interaction between macromolecules and ligands, providing an understanding on how biological macromolecules with ligands interactions are central to facilitating the discovery, design, and development of future, functional foods. In addition, it outlines information available on the macromolecules-ligands interaction that happens inside the food matrixes and inside our bodies.Knowing about the mechanisms responsible for the macromolecules-ligands recognition and binding facilitates the discovery, design, and development of future and functional foods.
Polyamine-Phytohormone-Nutrient Network: Nexus in Plant Responses to Abiotic Stresses presents the latest global research on the these important tools for improving physiological / biochemical molecular mechanisms for improved plant health and production. Exposure of plants (crop and non-crop) to abiotic stresses is inevitable; hence, impairments in plant growth, metabolism and productivity due to abiotic stresses seem obvious. Naturally, plants are endowed with endogenous chemicals including intracellular messengers and signalling molecules to counteract the potential stress-impacts, protect cellular functions, and grow and produce well. Polyamines (PAs) are low molecular weight nitrogen- containing compounds with aliphatic polycationic properties. In addition to their roles in diverse growth and development processes, Pas(such as putrescine, spermidine, and spermine) have been implicated in improving plant tolerance to abiotic stresses. On the other hand, PAs have their close relation with both phytohormones (such as cytokinins, abscisic acid, auxins, gibberellins and gaseous hormone ethylene), and most mineral nutrients (such as N and S). Interestingly, the interactive response and outcomes of PAs with either phytohormones or mineral nutrients could exhibit synergistic or antagonistic effects. Thus, either the functions of PAs can be modulated by phytohormones and mineral nutrients; or the cellular/organ or whole plant level PAs may potentially affect the role of both phytohormones and mineral nutrients. With a globally diverse team of expert contributors, this book focuses on the PA-phytohormone-mineral nutrient interactions that is significant for establishing connections between nutrient assimilation, C-fixation, and secondary metabolic pathways.