Nanomaterials in the Plant-Soil Continuum explores the various nanomaterials that are impacting agriculture whether through intentional or unintentional pathways. Providing a concise outlook of NMs in soil chemistry, physics, and biology, it highlights nanomaterial transformation in soil and subsequent plant uptake. Plants may be exposed to naturally generated or artificially produced nanomaterials (ENMs). They can absorb NMs from the soil through roots or leaves but return them to the soil through litter, creating an intricate network of NMs cycling in a soil-plant continuum. Understanding this NM transformation in soil and subsequent plant uptake is integral to understanding, and protecting, an ecosystem. Nanomaterials in the Plant-Soil Continuum also discusses the translocation and biotransformation of NMs in plants and their effects on plant metabolism. Considering NMs as new and emerging agrochemicals, a detailed understanding of their role in the soil-plant continuum, ecosystem functioning, and services will also be discussed. This volume in the "Nanomaterial Plant Interactions" series highlights the recent insights into the impact, fate, and transport of NMs in the soil-plant continuum and their potential impacts on soil and plant health.
Atlas of Endoscopy Imaging in Inflammatory Bowel Disease, Second Edition, serves as a comprehensive guide to the latest advancements in IBD. This new edition keeps readers updated with cutting-edge medical treatments, state-of-the-art endoscopy, and imaging technologies, as well as the evolution of interventional IBD. It explores the latest advancements in IBD diagnosis and management, including the most recent endoscopy instruments for measuring disease activity and the transformative world of image-enhanced endoscopy. Additionally, it delves into the groundbreaking application of Artificial Intelligence (AI) in IBD, revolutionizing diagnosis, disease monitoring, and dysplasia surveillance. New content introduces a range of topics to stay at the forefront of Inflammatory Bowel Disease (IBD) knowledge. These include Intestinal Ultrasound, Device-Associated Enteroscopy in Crohn’s Disease, insights into IBD-Like Conditions (Autoinflammatory Disorders), and the value of Intraoperative Endoscopy in IBD procedures. The book also integrates New Consensus Guidelines for Endoscopy Imaging in IBD, explores the Applications of Artificial Intelligence (AI) in IBD diagnosis and monitoring, addresses the intersection of COVID, COVID Vaccines, and IBD, and presents New Applications of Interventional IBD techniques. This second edition serves as a dynamic repository of state-of-the-art information, providing invaluable insights on differential diagnosis, advanced endoscopy, and imaging technologies, with a pronounced focus on AI. It also offers updated guidelines for disease activity assessment and the latest advancements in endoscopic therapy modalities. Designed to cater to a diverse range of medical professionals, it stands as an indispensable reference, fostering a comprehensive and up-to-date understanding of Inflammatory Bowel Disease (IBD). Within these pages,Gastroenterologists and IBD specialists will discover a wealth of resources to aid their pursuit of cutting-edge treatments and AI-driven insights. Primary care clinicians will find an expanded list of differential diagnoses that enables more accurate early-stage identification. Surgeons can elevate their expertise by delving into the intricacies of interventional IBD techniques, while pathologists and radiologists can enhance their diagnostic skills through AI and image-enhanced endoscopy. This comprehensive resource ensures that medical professionals across various disciplines are well-equipped to navigate the evolving landscape of IBD diagnosis, treatment, and management.
Immuno-oncology and immunotherapy, Part D, Volume 196 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Extraction and quantification of histones from human cells, Expression and characterization of Phosphatidylserine-targeting antibodies for biochemical and therapeutic applications, ILC differentiation from HSCs in vitro, Methods to expand human Treg cells and assay their function, Monitoring rapid activation of human gamma/delta T cells by multicolor flow cytometry, Methods to induce T cell exhaustion in vitro, Ex vivo assessment of human neutrophil motility and migration, and much more.Additional chapters focus on Flow cytometry-based monitoring of myeloid-derived suppressor cells in the peripheral blood of patients with solid tumors, Deciphering human blood and tumor neutrophil heterogeneity: Methods for isolation and assessing suppression of T-cell proliferation, Splenocyte anticancer citotoxicity assessment after prophylactic vaccination or drug treatment of tumor-bearing mice, Therapeutic treatment of tumor-bearing mice with drug-killed cancer cells: a method to confirm immunogenic cell death and assess its therapeutic effectiveness, and much more.
Pharmacology of Ketamine: Fundamentals, Applications, Delivery Systems and Clinical Aspects explores the multifaceted properties of ketamine for diverse applications, delving into dosing strategies, routes of administration, and their pharmacological implications. The book begins with an introduction that underscores the need to bridge research and practice. It then delves into the pharmacological intricacies of ketamine, dissecting mechanisms and dosing strategies and exploring the diverse routes of administration and their impact on ketamine's metabolites.The book then explores the PK and PD characteristics of ketamine, followed by a deep dive into clinical applications emphasizing anesthesia, psychiatric therapy, and emerging treatments. The final part of the book covers addiction, toxicity, and future research perspectives. It will serve as a comprehensive reference tailored to the needs of both researchers and clinicians involved in the administration and study of ketamine.
High Intensity Functional Training: Clinical Applications in Training, Rehabilitation, and Sport presents a clear definition of high intensity functional training (HIFT) in medical literature while also examining how HIFT can be used as an exercise/training modality, a rehabilitation protocol, and as a competitive sport unto itself. Topics covered move from the data in the research, the implications to specific patients, and rehabilitation outcomes. Chapter authors are all subject matter experts, some of whom have designed and implemented studies regarding this training modality.This comprehensive book provides a solution on training and the sport, and how to best care for these athletes.
When synthetic drugs produce adverse side effects, practitioners may look to natural alternatives to alleviate symptoms or complement existing treatment. Therapeutic Potential of Medicinal Plants: The Science Behind Natural Remedies, investigates the bioactive compounds and functionality of medicinal plants and herbs which are recommended to help certain health conditions and overall well-being while highlighting cultivation that can be done sustainably to promote biodiversity conservation. Written by over 50 experts in the fields of nutrition, organic food, fertility, phytopharmacology, biotechnology, nanotechnology, plant botanicals, and herbal medicine, “Therapeutic Potential of Medicinal Plants: The Science Behind Natural Remedies,” introduces readers to the the chemical composition of over 75 plants, herbs, grains and seeds while highlighting their anti-inflammatory, antimicrobial, antioxidant, and immunomodulatory effects to improve overall well being and manage certain conditions such as diabetes, osteoarthritis, cardiovascular and neurodegenerative diseases. Bioactive compounds, essential oils and phytochemicals in certain plants and marine compounds are reviewed for their efficacy to help improve gynecological health, alleviate menopausal symptoms and lower blood pressure. The book also discusses the toxicity and safety implications associated with the use of medicinal herbs during pregnancy and other life stages.
Preventable Medical Errors: The Role of Different Sciences in Medical Education and Practice addresses the issues of staying up to date with evolving medical practices, by providing practical examples linked to real-world patient safety concerns and illustrating theoretical discussions with clear clinical practice scenarios. The book is divided into two sections, Part 1 - How Did It Come To This? and Part 2 - Where Does It Go From Here?; which guide the reader through how we got here historically and how we can navigate our way out using the tools the author presents. Thus paving the way, bridging a gap between theory and practice, while emphasizing the importance of patient safety. Written for all medical professionals, at the forefront of postmodern and scientific medical advancements, to ultimately improve clinical outcomes and reduce preventable medical errors.
Targeted Protein Degradation Technologies provides a thorough overview of targeted protein degradation from the latest developments in the field to potential therapeutic applications. The book begins with an introduction to the mechanisms of protein degradation followed by a section covering both protease-mediate degradation and lysosome-mediate degradation. A range of cutting-edge technologies are covered, including PROTAC, AbTAC, molecular glues, hydrophobic tagging, LYTAC, GlueTAC and AUTAC. Degraders of specific proteins are then investigated, including signal transduction receptors, membrane proteins, and transcription factor degraders.The book closes with a section on the clinical applications of targeted protein degradation and a look at future perspectives. It is a useful resource to those in the fields of molecular biology, cell biology, and related areas working with protein degradation and the development of therapeutic technologies in this arena.
Aging in Ophthalmology examines the aging process of the eye and how this affects the future of ophthalmology. With a strong focus on therapeutic options, the book shows the latest improvements in medical and surgical possibilities. It describes both the risks of the aging of the eye, the aging of different parts of the eye (like the retina, lens, and iris), therapeutic approaches to limit the aging processes of the eye, along with a glance into the future. This book is a valuable resource for ophthalmologists of all subspecialties and researchers interested in the aging process in the human eye.
Aquaculture Mycology and Bacteriology is a practical reference to address the steadily increasing importance of infectious diseases of aquatic animals. With the burgeoning expansion of the animal aquaculture industry to new geographic areas, new microbial and parasitic species with pathogenic potential will continue to emerge. This necessitates rapid identification of the new pathogens to enable their control. Each pathogenic bacterial or fungal species is accompanied by the full description of both taxonomic and clinical information for the three major aquatic food animals (fish, crustaceans and mollusks). The book takes a comprehensive approach to facilitate research to develop vaccines or other similar pathogen mitigation measures, and is useful to bacteriologists, mycologists, aquaculturists, clinical practitioners in aquatic animal health and all those in industry, government or academia who are interested in aquaculture, fisheries and comparative biology.