Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

Books Journals

Essentials of Translational Pediatric Drug Development

1st Edition
July 22, 2024
Elke Gasthuys + 3 more
English
Paperback
9 7 8 0 3 2 3 8 8 4 5 9 4
eBook
9 7 8 0 3 2 3 9 0 4 2 9 2

Essentials of Translational Pediatric Drug Development: From Past Needs to Future Opportunities provides integrated and up-to-date insights relevant for both translational researchers and clinicians active in the field of pediatric drug development. The book covers all key aspects from different stakeholder perspectives, providing a literature overview and careful reflection on state-of-the-art approaches. It will be an ideal guide for researchers in the field who are designing and performing high quality, innovative pediatric-adapted drug development by helping them define needs/challenges and possible solutions that advance and harmonize pediatric drug development.Despite the broad consensus that children merit the same quality of drug treatment as any other age group, children remain frequently neglected during drug research and development. Even with the adoption of multiple legislations addressing this problem, the lack of efficacy and safety data of marketed as well as newly developed drugs still remain in the pediatric population.

Quality Assurance Management

1st Edition
July 20, 2024
Gayathri De Lanerolle + 3 more
English
Paperback
9 7 8 0 1 2 8 2 2 7 3 2 9
eBook
9 7 8 0 1 2 8 2 2 7 3 3 6

Quality Assurance Management: A Comprehensive Overview of Real-World Applications for High Risk Specialties demonstrates how to best design and implement standard operating procedures (SOPs) to ensure protocol and regulation adherence. The book showcases similarities and differences between healthcare and academic quality assurance systems, resulting in counter-productivity and performance issues, in addition to regulatory inspection preparedness. It uses the processes and standards of the UK to demonstrate how to combine QA and research building into ‘building blocks’ that share a common pathway for effective project design, analysis and unbiased interpretation of collated data.This book fills a gap, providing original research in QA that especially focuses on specialist areas. It will be of use to research and clinical staff working in clinical research within healthcare, academia and industry.

The Discovery of New Medicines in Academia

1st Edition
Volume 100
July 18, 2024
Diane Peters + 1 more
English
Hardback
9 7 8 0 4 4 3 2 9 3 2 4 5
eBook
9 7 8 0 4 4 3 2 9 3 2 5 2

The Discovery of New Medicines in Academia, Volume 100 highlight examples of discoveries originating in academia that have been successfully translated into promising therapeutics that have advanced into clinical trials. Chapters in this release cover Design and Discovery of Itaconate prodrugs for Alopecia Areata, Hydroxyl-Dendrimer Delivery System for Neurological Disease, Development of allosteric modulators of G protein-coupled receptors for Psychiatric Disease, Targeting the constitutively active ERK1/2 signaling kinase for cancer, mRNA reprogramming of myeloid cells for tumor immunotherapy, Development of novel drugs targeting protein-protein interactions, and much more.Additional sections cover Neuro-steroids and analogs for the treatment of epilepsy, Development of inhibitors of eukaryotic translation, Discovery/development of antiviral, anticancer and/or anti-inflammatory agents, Discovery of novel anti-infective agents, Targeting proliferating cell nuclear antigen (PCNA) for cancer, and Implementation and Evolution of Quantitative Systems Pharmacology to Patient Digital Twins and Biomimetic Twins.

Advancement of Phenolic Acids in Drug Discovery

1st Edition
June 19, 2024
Naresh Kumar + 2 more
English
Paperback
9 7 8 0 4 4 3 1 8 5 3 8 0
eBook
9 7 8 0 4 4 3 1 8 5 3 9 7

Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. Chapters overview phenolic acids and their characterization, discuss the role of phenolic acids in plant systems, present sources and detailed extraction methods of phenolic acids, and cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases. The book’s final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. This is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science and medicinal chemistry will also benefit from this in-depth profiling of therapeutical properties of phenolic acids.

The Diagnosis and Treatment of Protozoan Diseases

1st Edition
May 29, 2024
Tarun Kumar Bhatt
English
Paperback
9 7 8 0 4 4 3 1 9 1 6 1 9
eBook
9 7 8 0 4 4 3 1 5 2 4 5 0

The Diagnosis and Treatment of Protozoan Diseases discusses major protozoan diseases such as Malaria, Leishmaniasis, etc., including other clinically minor protozoan diseases. This book provides all essential information to professional researchers and medical personnel about the disease, causative organism, and their lifecycle, diagnostics, and treatments, including drugs and vaccine, resistance, and key points of future research. Infectious diseases are accountable for millions of deaths every year throughout the globe. Among them, significant contributors are protozoan parasites.Despite the many research group working on the various protozoan diseases, there are still major gaps to fill. The authors of this book have critically reviewed all the aspects of major protozoan diseases, their diagnostics, and treatments, including resistance.

Pharmacology in Drug Discovery and Development

3rd Edition
May 21, 2024
Terry P. Kenakin
English
Paperback
9 7 8 0 4 4 3 1 4 1 2 4 9
eBook
9 7 8 0 4 4 3 1 4 1 2 5 6

Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition is an introductory resource that illustrates how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization.The updates to the Third Edition include a new section converting “descriptive” data into “predictive” data through comparison to mathematical models, expansion on enzymes, drug metabolites and drug–drug interactions, and two new chapters. The newly developed companion website hosts further educational resources to complement the book. As in previous editions, this new edition includes numerous valuable chapter summaries, detailed references, practical examples, and case studies throughout.

Progress and Prospect of Nanocarriers

1st Edition
May 6, 2024
Sushil K. Kashaw + 2 more
English
Paperback
9 7 8 0 1 2 8 1 9 9 7 9 4
eBook
9 7 8 0 3 2 3 9 0 3 1 1 0

Progress and Prospect of Nanocarriers: Design, Concept, and Recent Advances examines the different nanocarriers that are currently being developed for specific applications in biomedical drug delivery, disease management, diagnosis and therapy. Nanosized drug delivery systems have gained tremendous amounts of clinical interest due to their effective bio-distribution and enhanced pharmacokinetic and selective targeting capability which results in high therapeutic potential, low side effects, and the generation of cost-effective drug delivery systems. Numerous effective nanocarriers have been evolving, including polymeric nanoparticles, liposomes, microspheres, dendrimers, and carbon nanotubes.This book is a helpful reference for scientists and students in the fields of drug delivery, biomaterials and nanomedicine, as well as scientists and engineers in industrial disciplines of drug delivery and drug formulation.

Rang y Dale. Farmacología

10th Edition
May 15, 2024
James M. Ritter + 4 more
Spanish

Nueva edición del texto clásico en Farmacología y de referencia para los estudiantes de Medicina en el que se aborda de forma exhaustiva, pero clara y organizada el mecanismo de acción de los fármacos más comúnmente usados, tanto a nivel molecular o celular, como de los mecanismos fisiológicos sobre los que actúan.Se ha mantenido la organización general del libro, dividido en 6 grandes secciones en las que se ofrece una descripción de los efectos y usos de los diferentes fármacos junto con su acción sobre las vías de señalización subyacentes a todos los procesos fisiológicos que ocurren en el ser humano. En cuanto a las novedades, si bien todos los capítulos se han actualizado, algunos de ellos han sufrido grandes cambios. Así cabe destacar: Cap 5 (se han incluido un mayor número de fármacos RNA), Cap 24 (recientes avances en la medición de la presión de oxígeno), Cap 40 (se ha puesto el foco en el Alzheimer y la demencia vascular y la asociada a los cuerpos de Levy), Cap 43 (nueva sección destinada al tratamiento del dolor crónico), Cap 51 (nuevos diagramas que ilustran los lugares de acción de los antibióticos a nivel de los ribosomas), Cap 53 (información sobre el modo de replicación de los retrovirales y una sección específica de Covid19) y Cap 57 ( gran y amplia cobertura de los nuevos fármacos anticancerosos). Se ha introducido dos nuevos capítulos. Uno de ellos dedicado a la Farmacología ocular y otro dedicado al tratamiento farmacológico de la migraña en el que se incluyen los nuevos antagonistas de CGRP y su uso profiláctico para la migraña. La nueva edición incluye acceso al e-book en español en el que se incluye contenido adicional (casos clínicos y preguntas de autoevaluación) también en español.

Therapeutic Drug Monitoring

2nd Edition
April 26, 2024
Amitava Dasgupta
English
Hardback
9 7 8 0 4 4 3 1 8 6 4 9 3
eBook
9 7 8 0 4 4 3 1 8 6 5 0 9

Therapeutic Drug Monitoring: Newer Drugs and Biomarkers, Second Edition is an updated reference on TDM analytical techniques in diverse clinical settings. This new edition reviews exciting new developments in the area, including seven new chapters covering immunoassay design and applications, combined chromatographic techniques in therapeutic monitoring, drug monitoring in alternative specimens, pharmacogenomics of anticancer drugs, pharmacogenomics testing for patient management, selected antifungal agents, pharmacodynamic monitoring, and therapeutic drug monitoring of selected anticoagulants. All remaining chapters in the first edition were thoroughly revised and updated.This book is the ideal reference for clinical pathologists, pharmacologists, and toxicologists involved with TDM. Scientists working in diagnostic companies, developing reagents for monitoring therapeutic drugs will also find relevant information in this book.

Brody's Human Pharmacology

7th Edition
January 31, 2024
Lynn Wecker + 1 more
English

Brody’s Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives. What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals.

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