Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

Books Journals

31-40 of 811 results in All results

Exosome Communication

1st Edition
November 15, 2024
Dilapathi Gugulothu + 3 more
English
Paperback
9 7 8 - 0 - 4 4 3 - 2 9 0 5 2 - 7
eBook
9 7 8 - 0 - 4 4 3 - 2 9 0 5 3 - 4

Exosome Communication: Advances in Research and Therapeutics for Health and Disease is a reference tailored for pharmaceutical scientists and covers the key qualities of exosomes as drug delivery vehicles. Exosomes are intracellular membrane-based vesicles with diverse compositions, offering advantages over other drug delivery systems like liposomes and polymeric nanoparticles due to their non-immunogenic nature. This book provides a comprehensive exploration of exosomes, starting with their history and development, understanding extracellular vesicles and biogenesis, and techniques for isolation and characterization. It also delves into cargo loading, release strategies, and their potential applications in diagnostics and various diseases, including antigen-specific delivery, gene delivery, and vaccine delivery, highlighting how engineering exosomes can enhance therapeutic efficacy. The book also addresses critical considerations like quality control, heterogeneity reduction, regulatory and ethical aspects, clinical trials, and scale-up manufacturing. By providing a comprehensive and detailed overview of exosome-based therapeutics' potential, "Exosome Communication: Advances in Research and Therapeutics for Health and Disease" serves as a valuable reference for those interested in exploring exosomes' applications in drug delivery and therapeutics.

Quinone-Based Compounds in Drug Discovery

1st Edition
November 1, 2024
Umar Ali Dar + 2 more
English
Paperback
9 7 8 - 0 - 4 4 3 - 2 4 1 2 6 - 0
eBook
9 7 8 - 0 - 4 4 3 - 2 4 1 2 5 - 3

Quinone-Based Compounds in Drug Discovery: Trends and Applications provides a comprehensive and up-to-date overview of the latest advances in the field of drug discovery using quinone-based materials.This book covers various aspects of quinone-based materials such as their synthesis, characterization, and applications in drug discovery, consolidating current research on a single volume. The book introduces quinones in the pharmacology context and then describes the current developments in the development of drugs for key diseases and conditions. The final chapters deal with the regulatory and commercial framework to take quinone-based drugs to the market.Quinone-Based Compounds in Drug Discovery: Trends and Applications benefits a wide range of readers including researchers, scientists, and graduate students in the field of drug discovery, Chemists and biochemists will also benefit from the contents of this book.

Annual Reports on Medicinal Chemistry

1st Edition
Volume 63
November 1, 2024
Radim Nencka
English
Hardback
9 7 8 - 0 - 4 4 3 - 2 9 5 8 4 - 3
eBook
9 7 8 - 0 - 4 4 3 - 2 9 5 8 5 - 0

Annual Reports on Medicinal Chemistry: PROTAC and similar technologies Volume 63 in this series Annual Reports on Medicinal Chemistry, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

Progress in Medicinal Chemistry

1st Edition
Volume 63
November 1, 2024
Jonathan Bentley + 1 more
English
Hardback
9 7 8 - 0 - 4 4 3 - 2 9 7 8 0 - 9
eBook
9 7 8 - 0 - 4 4 3 - 2 9 7 8 1 - 6

Progress in Medicinal Chemistry, Volume 63 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Specific chapters in this release include Harnessing conformational drivers in drug design, Recent Advances in the Medicinal Chemistry of Heterobifunctional Derivatives for Protein Homeostasis, and A Decade of Antimalarial Drug Discovery: New Targets, Tools and Molecules.

Annual Reports in Medicinal Chemistry: Roadmaps

1st Edition
Volume 62
October 1, 2024
Katherine Seley-Radtke
English
Hardback
9 7 8 - 0 - 4 4 3 - 2 9 6 1 0 - 9
eBook
9 7 8 - 0 - 4 4 3 - 2 9 6 1 1 - 6

Annual Reports in Medicinal Chemistry: Roadmaps, Volume 62 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. This release provides a compendium of information on newly approved drugs and compounds entering late-stage clinical trials, making it a valuable resource for graduate students pursuing research in medicinal chemistry

mRNA Therapeutics

1st Edition
September 2, 2024
Anya Hillery
English
Paperback
9 7 8 - 0 - 4 4 3 - 2 8 9 3 4 - 7
eBook
9 7 8 - 0 - 4 4 3 - 2 8 9 3 5 - 4

mRNA Therapeutics: Foundations, Innovations, and Clinical Applications summarizes the scientific development of mRNA vaccines that have revolutionized the way we treat disease. This approach has the potential to treat a wide range of diseases, including COVID-19, cancer, and infectious diseases. The first section of the book introduces mRNA vaccines, including their history, mechanism of action, and potential applications. The second section delves into the science of mRNA vaccines, covering topics such as the structure of mRNA, the delivery of mRNA to cells, and the immune response to mRNA vaccines.The third section discusses the future of mRNA technology, exploring potential applications such as cancer therapy, prevention of infectious diseases, and replacement of missing or damaged proteins. This is a valuable resource for scientists, researchers, and clinicians who are interested in the latest developments in mRNA technology. It is also a useful reference for students and professionals who are working in the fields of biotechnology, pharmaceutical science, and vaccine development.

TRP Channels as Therapeutic Targets

2nd Edition
August 26, 2024
Arpad Szallasi
English
Hardback
9 7 8 - 0 - 4 4 3 - 1 8 6 5 3 - 0
eBook
9 7 8 - 0 - 4 4 3 - 1 8 6 5 4 - 7

TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use, Second Edition is a comprehensive reference on the roles of TRP Channels in health and disease states. Chapters are completely updated, withe new topics on TRP channels biology, the crystalline structure of TRP channels, targeting TRP channels for pain relief, the relationship with migraine, emerging pain targets, a comprehensive view of the role of TRP channels in respiratory diseases and COVID complications, anxiety relief, renal disease, arthritis, and therapeutic opportunities for thermal regulation. This is a great reference for broad segments of the scientific and medical community. Researchers working on TRP channel drug discovery will benefit from the overview of applications to conditions in specific organ systems. Clinicians interested in new drugs in the pipeline will also find this book helpful for biologic principles of action.

Essentials of Translational Pediatric Drug Development

1st Edition
July 22, 2024
Elke Gasthuys + 3 more
English
Paperback
9 7 8 - 0 - 3 2 3 - 8 8 4 5 9 - 4
eBook
9 7 8 - 0 - 3 2 3 - 9 0 4 2 9 - 2

Essentials of Translational Pediatric Drug Development: From Past Needs to Future Opportunities provides integrated and up-to-date insights relevant for both translational researchers and clinicians active in the field of pediatric drug development. The book covers all key aspects from different stakeholder perspectives, providing a literature overview and careful reflection on state-of-the-art approaches. It will be an ideal guide for researchers in the field who are designing and performing high quality, innovative pediatric-adapted drug development by helping them define needs/challenges and possible solutions that advance and harmonize pediatric drug development.Despite the broad consensus that children merit the same quality of drug treatment as any other age group, children remain frequently neglected during drug research and development. Even with the adoption of multiple legislations addressing this problem, the lack of efficacy and safety data of marketed as well as newly developed drugs still remain in the pediatric population.

Quality Assurance Management

1st Edition
July 20, 2024
Gayathri De Lanerolle + 3 more
English
Paperback
9 7 8 - 0 - 1 2 - 8 2 2 7 3 2 - 9
eBook
9 7 8 - 0 - 1 2 - 8 2 2 7 3 3 - 6

Quality Assurance Management: A Comprehensive Overview of Real-World Applications for High Risk Specialties demonstrates how to best design and implement standard operating procedures (SOPs) to ensure protocol and regulation adherence. The book showcases similarities and differences between healthcare and academic quality assurance systems, resulting in counter-productivity and performance issues, in addition to regulatory inspection preparedness. It uses the processes and standards of the UK to demonstrate how to combine QA and research building into ‘building blocks’ that share a common pathway for effective project design, analysis and unbiased interpretation of collated data.This book fills a gap, providing original research in QA that especially focuses on specialist areas. It will be of use to research and clinical staff working in clinical research within healthcare, academia and industry.

The Discovery of New Medicines in Academia

1st Edition
Volume 100
July 18, 2024
Diane Peters + 1 more
English
Hardback
9 7 8 - 0 - 4 4 3 - 2 9 3 2 4 - 5

The Discovery of New Medicines in Academia, Volume 100 highlight examples of discoveries originating in academia that have been successfully translated into promising therapeutics that have advanced into clinical trials. Chapters in this release cover Design and Discovery of Itaconate prodrugs for Alopecia Areata, Hydroxyl-Dendrimer Delivery System for Neurological Disease, Development of allosteric modulators of G protein-coupled receptors for Psychiatric Disease, Targeting the constitutively active ERK1/2 signaling kinase for cancer, mRNA reprogramming of myeloid cells for tumor immunotherapy, Development of novel drugs targeting protein-protein interactions, and much more.Additional sections cover Neuro-steroids and analogs for the treatment of epilepsy, Development of inhibitors of eukaryotic translation, Discovery/development of antiviral, anticancer and/or anti-inflammatory agents, Discovery of novel anti-infective agents, Targeting proliferating cell nuclear antigen (PCNA) for cancer, and Implementation and Evolution of Quantitative Systems Pharmacology to Patient Digital Twins and Biomimetic Twins.