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Books in Psychoneuropharmacology

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11-20 of 36 results in All results

Antipsychotic Drugs and Their Side-Effects

  • 1st Edition
  • October 22, 2013
  • Thomas R.E. Barnes + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 8 8 1 0 - 9
In line with other volumes in the Neuroscience Perspectives Series, this volume covers the background, pharmacology, molecular biology, and biochemistry of antipsychotic drugs, together with an overview assessment of the therapeutic considerations. Over the past 40 years, the effectiveness of conventional neuroleptic agents for psychotic illness has been offset by a wide range of adverse side-effects, including motor side-effects like parkinsonism. Studies show that lowering doses may still produce the antipsychotic effect while lessening the risk of side-effects. As all available antispychotic drugs are able to block dopamine, specifically D2 receptors, doses below the threshold level for producing acute motor disorder can still be therapeutically effective. With the identification and characterization of multiple dopamine receptors, the possibility of more selective drugs with better side-effect potential has arisen. Other novel antipsychotic agents include D1 receptor blockers, partial dopamine agonists and non-dopamine drugs such as 5-HT receptor blockers, sigma receptor antagonists and NMDA receptor agonists. This volume reviews both the basic science of the conventional and atypical neuroleptics and their present and potential therapeutic use.

Brain Browser

  • 1st Edition
  • October 22, 2013
  • Floyd E. Bloom
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 8 4 9 3 - 4
Brain Browser is designed to assist researchers as well as beginning and advanced neuroscience students in their efforts to organize, analyze, and contribute to the growing detailed knowledge of the brain. Brain Browser serves as an electronic notebook for neuroanatomy and offers numerous educational and research applications.For the Student:Learn the organization and structure of the rat brainOrganize your knowledge of brain function and structureStore neuroanatomical references and terms in an efficient mannerFor the Advanced Neuroscientist:Add your own experimental results and build a personal databaseOrganize and recall multiple items of complexly interrelated dataDevelop a more efficient and organized way to write papers and do researchBrain Browser consists of four main Hypertext stacks:Learner introduces the beginner to rat brain organization and provides elementary coverage of circuits, cells, and neurotransmitters.NeuroNavigator presents a computer atlas based on The Rat Brain: In Stereotaxic Coordinates, by George Paxinos and Charles Watson (Academic Press, Second Edition, 1986).Linker is an extensive database of neuronal circuitry (the afferent and efferent connections between brain locations).DataMaker enables users to add or modify templates of the atlas plates with their own data.In addition, the Reference program, containing more than 320 references, links any desired reference to any data point. The Dictionary defines terms used in Brain Browser and allows users to add new entries.The program includes five high-density disks, a user's manual, and a complete tutorial. User support is provided by electronic mail on CompuServe(r). Department site licenses are available, as well as a buyer's frequency plan. Contact the publisher for complete details.Brain Browser(tm) is a trademark of The Scripps Research Institute.PLUS(tm) is a trademark of Spinnaker Software CorporationMicrosoft(r) Windows(tm) is a trademark of Microsoft Corporation.IBM(r) is a registered trademark of International Business Machines, Inc.CompuServe(r) is a registered trademark of CompuServe, Inc.Macintosh(r) is a registered trademark of Apple Computer Inc.Hypercard(r) is a registered trademark of Apple Computer Inc.Intel(r) is a registered trademark of Intel Corporation.

Metal Toxicology

  • 1st Edition
  • October 22, 2013
  • Robert A. Goyer
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 8 8 5 6 - 7
Metal Toxicology addresses the effects of metals on human health, as well as their mechanisms of toxicity. Unlike most books on metal toxicity which are organized by individual metals, this book is arranged inan organ-by-organ basis. It deals with unifying mechanisms of metal toxicity within a given tissue, and with exposure of a tissue to more than one metal at a time.

Methods in Behavioral Pharmacology

  • 1st Edition
  • Volume 10
  • October 22, 2013
  • F. van Haaren
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 9 0 2 4 - 9
Methods in Behavioral Pharmacology is unique in offering a complete description and critical evaluation of most, if not all, methods available to study the effects of drugs on behavior. It stands apart in that it is not limited to the analysis of a particular class of pharmacological agents in a limited number of paradigms. Methods in Behavioral Pharmacology covers all paradigms without reference to specific pharmacological compounds.The book provides a comprehensive overview of the methodology used to study the behavioral effects of legal and illegal drugs. It also provides an in-depth presentation of dependent variables, their quantification and a critical evaluation of their advantages and disadvantages. An excellent work, contributed to by well-known experts in the different fields of behavioral pharmacology.

Animal and Translational Models for CNS Drug Discovery: Psychiatric Disorders

  • 1st Edition
  • October 6, 2008
  • Robert A. McArthur + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 7 3 8 5 6 - 1
  • eBook
    9 7 8 - 0 - 0 8 - 0 9 2 0 3 9 - 9
Psychiatric Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders such as anxiety, obsessive-compulsive disorder, depression, schizophrenia, bipolar disorder, ADHD, and autistic spectrum disorder. Psychiatric Disorders has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the first volume in the three volume-set, Animal and Translational Models for CNS Drug Discovery 978-0-12-373861-5, and is also available for purchase individually.

Encyclopedia of Violence, Peace, and Conflict

  • 1st Edition
  • August 10, 1999
  • Lester R. Kurtz
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 4 4 1 4 - 4
The Encyclopedia of Violence, Peace, and Conflict, a three-volume set written by more than 200 eminent contributors from around the world, takes advantage of increasing, worldwide awareness in the public, private, commercial, and academic sectors about manifestations of violence in all segments of society. While the contributors do not use these volumes to make specific arguments, they do describe and clarify the developments in thought that have led to current theories about and positions on violence and peace. Our reviewers consistently note that while many in-depth studies of war, peace, and aggression exist, the attendant specialization keeps scholars from learning about related fields. No publication competing with the Encyclopedia of Violence, Peace, and Conflict can satisfy their need for a vast introductory work to such a diverse and socially-important field. This major work includes more than 190 multidisciplinary articles with over 1,000 cross-references and more than 2,000 bibliography entries for further reading which are arranged alphabetically for easy access.

Cumulative Subject Index

  • 1st Edition
  • Volume 45
  • October 16, 1998
  • J. Thomas August + 3 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 8 1 3 7 - 8
Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. For easy reference, this volume provides a cumulative subject index covering Volumes 25-44.

Cytokines

  • 1st Edition
  • April 15, 1998
  • Anthony R. Mire-Sluis + 1 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 3 0 2 1 - 5
This book provides comprehensive coverage of the cytokines from a pharmacological approach. The chapters are presented in a consistent format allowing easy cross-reference, with sample diagrams and a summary table of essential facts for each chapter at the end of the book.Cytokines is unique in stressing cytokine biology and the application of research data to provide disease therapy. With 33 detailed and up-to-date chapters about individual cytokines, this comprehensive reference will provide both clinicians and researchers in immunology and pharmacology with invaluable information.

Antioxidants in Disease Mechanisms and Therapy

  • 1st Edition
  • Volume 38
  • December 10, 1996
  • Lester Packer + 4 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 8 1 3 0 - 9
Antioxidants in Disease Mechanisms and Therapy presents molecular actions of natural and synthetic antioxidants and emphasizes the potential role in disease mechanisms and therapeutic strategies. The modulationof gene expression by the induction of antioxidant enzymes is a novel role beyond the direct antioxidant action. The volume explores the current state of knowledge on oxidants and antioxidants in disease processes, including arteriosclerosis, adult respiratory distress syndrome, cystic fibrosis, Down's syndrome, inflammation, cataract, age-related macular degeneration, afflications of the nervous system, AIDS, liver diseases, diabetes, skin diseases, and cancer.

International Review of Neurobiology

  • 1st Edition
  • Volume 39
  • December 2, 1996
  • Ronald J. Bradley + 2 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 8 5 7 7 3 - 2
Since 1959, International Review of Neurobiology has been a well known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. This important serial is now being combined with Neuroscience Perspectives and Methods in Neurosciences. This combination results in a series that reaches a wider audience and publishes a greater number of thematic volumes.