
Structure, Function and Regulation of TOR complexes from Yeasts to Mammals
Part A
- 1st Edition, Volume 27 - March 13, 2010
- Imprint: Academic Press
- Editors: Michael N Hall, Fuyuhiko Tamanoi
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 1 6 3 9 4 - 1
- Hardback ISBN:9 7 8 - 0 - 1 2 - 3 8 1 5 3 9 - 2
- eBook ISBN:9 7 8 - 0 - 1 2 - 3 8 1 5 4 0 - 8
Cell growth is highly regulated and is controlled by the TOR signaling network. Dysfunction of signaling pathways controlling cell growth results in cells of altered sizes and in… Read more

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Request a sales quoteThere has been an explosion of knowledge in this area in recent years and this volume provides an in-depth review of our current knowledge of TOR complexes by the leaders in the field.
- Contributions from leading authorities
- Informs and updates on all the latest developments in the field
Chapter 1: TOR complexes: composition, structure and phosphorylation
Mike Hall
Chapter 2: Regulation of TOR signaling in mammals
Dudley W. Lamming and David Sabatini
Chapter 3: Rheb G-protein and activation of mTORC1
Fuyu Tamanoi
Chapter 4: Regulation of TOR Complex1 by amino acids through small GTPases
Joe Avruch, Xiaomeng Long, Yenshou Lin, Sara Ortiz-Vega, Joseph Rapley, and Noriko Oshiro
Chapter 5: Rag GTPases in TORC1 activation and nutrient signaling
Li Li and Kun-Liang Guan
Chapter 6: Amino Acid Regulation of hVps34 and mTORC1 signaling
Pawan Gulati and George Thomas
Chapter 7: mTORC1 and cell cycle control
Chris Proud
Chapter 8: AGC Kinases in mTOR Signaling
Estela Jacinto
Chapter 9: TORC1 signaling in budding yeast
Robbie Loewith
Chapter 10: TORC2 and sphingolipid biosynthesis and signaling: Lessons from budding yeast
Ted Powers
Chapter 11: TORC1 signaling in the budding yeast endomembrane system and control of cell-cell adhesion in pathogenic fungi
Robert J. Bastidas and Maria Cardenas-Corona
Chapter 12: TOR and sexual development in fission yeast
Yoko Otsubo and Masayuki Yamamoto
Chapter 13: Fission yeast TOR and rapamycin
Ronit Weisman
Chapter 14: Structure of TOR complexes in fission yeast
Junko Kanoh and Mitsuhiro Yanagida
Chapter 15: The TOR complex and signaling pathway in plants
Christophe Robaglia, Bruce Veit and Christian Meyer
Chapter 16: Dysregulation of TOR Signaling in Tuberous Sclerosis and Lymphangioleiomyomotosis
Elizabeth Henske
Chapter 17: Chemistry and Pharmacology of Rapamycin and its Derivatives
Robert T. Abraham, James J. Gibbons and Edmund I. Graziani
- Edition: 1
- Volume: 27
- Published: March 13, 2010
- No. of pages (Hardback): 420
- No. of pages (eBook): 420
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780323163941
- Hardback ISBN: 9780123815392
- eBook ISBN: 9780123815408
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Michael N Hall
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