Structure and Function of Oxidation–Reduction Enzymes

Preface

Opening Address

In Memoriam of Otto Warburg

Functional Limits of Cytochrome c Variability

Vertebrates and Insect Haemoglobins: A New Haemcomplex

Comment on Article by G. Braunitzer

The Primary Structure of Soybean Leghemoglobin

Amino-Acid Sequence in Cytochrome c from Myxine glutinosa L

Chemical Synthesis of the Cytochrome c Molecule

The Primary Structure of Horse-Liver Alcohol Dehydrogenase

Tentative Amino-acid Sequence of Bovine-Liver Glutamate Dehydrogenase and Certain Properties of the Enzyme

Ferricytochrome c: II. Chain Flexibility and a Possible Reduction Mechanism

The Structure of Lactate Dehydrogenase at 2.8 Å Resolution

The Structure of Horse-Liver Alcohol Dehydrogenase. III. Molecular Structure at 5 Å Resolution

A Neutron Diffraction Analysis of Myoglobin: II. Hydrogen-Deuterium Bonding in the Main Chain

Structural Studies on Flavin Derivatives in Different States of Oxidation

Observation of Allosteric Transition in Hemoglobin

Comment on Article by S. Ogawa and R. G. Shulman

Myoglobin as a Possible Carrier of Oxygen

Subunit Interactions in Allosteric Control

Some Properties of Single-Chain Hemoglobins

A Fluorogenic Reagent as a Probe for the Subunit Structure of Glyceraldehyde-3- phosphate Dehydrogenase

Structural Changes of Cytochrome Oxidase Dependent on Its Redox State

Chemical Substitution of Heme Prosthetic Groups in Hemoproteins

Low-Temperature EPR Studies of the Effects of Protein Conformation on the Symmetry of Heme in High-Spin Ferriheme Proteins

Heme Binding and Biopolymer Conformation. The Interaction between Poly-α, L-Ornithine and Ferriprotoporphyrin IX

The Effects of Various Oestrogens on the Eosinofil Granulocytes in the Mouse and Rat Endometrium

Low-Spin Ferric Forms of Hemoglobin and Other Heme Proteins

Ligand Specificities of Interactions between Haemoglobin Protomers

Kinetics of the Reactions of Hemoglobin with Ligands. The Reaction of Hemoglobin, Isolated Chains and Intermediates with Ethylisocyanide

Role of Cytochromes and Other Metalloproteins in the Photosynthetic Electron Transport

Coupling and Control at the Cytochrome Level of Bacterial Photosynthetic Electron Transport

The Function of Cytochrome c in Mitochondrial Membranes

Formation of a Stable Complex between Cytochrome b2 and Cytochrome c and Study of Its Role in the Overall Electron Transfer by Rapid Kinetics

High-energy Forms of Cytochrome b

Studies of the Alkaline Transitions of Soluble Ferricytochrome b5

Substrate Interaction with Microsomal Cytochrome P-450

The Manifold of Peroxidase Function

Biological Effects of Hypochlorous Acid formed by "MPO"-peroxidation in the Presence of Chloride Ions

NMR Double-Resonance Study of Cytochrome c

Alternative Molecular Forms of Erythrocyte Catalase

Proton Magnetic Relaxation Enhancement of Cytochrome c

Kinetic and Equilibrium Studies on the Autoreduction of Horse-heart Ferricytochrome c

Peroxidase Activity of Haem c and Haem c Disulphone

Flavin-Dependent Substrate Dehydrogenation : Model Studies and Mechanisms

EPR and ENDOR Studies on Flavoprotein Radicals

Proton Relaxation Rate Enhancement with Free and Protein-bound Flavin Radicals

Thermodynamics and Kinetics of the Intramolecular Complex in Flavin-Adenine Dinucleotide

D-Amino Acid Oxidase

Riboflavin Flavoprotein from Egg-Yolk

On the Kinetics of Glutathione Reductase

DT Diaphorase—Reaction Mechanism and Metabolic Function

The Role of Flavins in Hydroxylase Reactions

Studies on the Mechanism of Salicylate Hydroxylase

Structure and Reaction Mechanism of Lipoamide Dehydrogenase from Pig Heart

Kinetic and Redox Properties of Flavoproteins in Mitochondria

The Covalently Bound Flavin Active Center of Succinate Dehydrogenase

Studies on the Catalysis of Hydrogen Exchange between (S')-(—)-Chlorosuccinate and Water by Succinic Dehydrogenase

Chemical Activation of Reconstitutively Inactive Succinate Dehydrogenase

Studies on the Copper Ions in Rhus-laccase

Structure of Microbial Iron Transport Compounds

A Rapid Method for Studying the Binding of Small Ions and Molecules to Macromolecules: Continuous Enthalpy Titration

Kinetics of Enzyme-Substrate Reactions in Single Living Cells

Relationship of Electron Transport Enzymes to Microsomal Membranes

Formylglycinamide Ribonucleotide Amidotransferase: A Brief Review

The Order of Addition of Substrates to Amino Acid: tRNA Ligases

Excitation Transfer between the Subunits of Liver Alcohol Dehydrogenase

The Use of Chloride Ion as Reporter Group for Changes in Protein Conformation. A 35C1 NMR Study of the Binding of Coenzyme and Inhibitors to Horse-liver Alcohol Dehydrogenase

Carboxymethyl-Liver Alcohol Dehydrogenase and Binding Studies with Iodoacetate and Pyridoxal Phosphate

Binding of Coenzyme to Native and Zinc-free Horse-liver Alcohol Dehydrogenase

Ternary Complexes of Horse-liver Alcohol Dehydrogenase, Oxidized Coenzyme and Fatty-Acid Amides

Rat-Liver Alcohol Dehydrogenase (RLADH)

Glyceraldehyde 3-Phosphate Dehydrogenase

Solvent Effects on NADH Fluorescence in Solution and in Complexes with Alcohol Dehydrogenase and Hydroxysteroid Dehydrogenase

Inhibition of LADH by Berberine and Some Related Alkaloids

Transfer of Hydrogen from Ethanol to Steroids during Ethanol Metabolism in the Rat

Studies on the Regulation of Ethanol Oxidation in Man

Physico-Chemical Studies of Glutamate Dehydrogenase in Solution

Complexes of Pyridine Nucleotides and Their Function

Rat-liver Lactate Dehydrogenase-Coenzyme (or Analog) Complexes: Difference Spectrophotometric Study

Is there a Glycolytic Particle?

Negative Interactions in the Glutamate Dehydrogenase Reaction

General Relationships between Dalziel Coefficients and Velocity Constants in the Random-order Two-substrate Mechanism

Studies of Dehydrogenase Mechanisms using ADP-Tetramethylpiperidine-1-oxyl (ADP-R—P), a Paramagnetic Analog of NAD

The Analysis of Transients in NAD+-linked Dehydrogenases

Comment on Article by J. D. Shore and H. Gutfreund

Concluding Remarks

Index