
Stimuli-Responsive Hydrogels for Ophthalmic Drug Delivery
- 1st Edition - May 8, 2024
- Imprint: Woodhead Publishing
- Authors: Dipankar Chattopadhyay, Jonathan Tersur Orasugh, Anjan Adhikari, Suprakas Sinha Ray
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 9 1 5 6 - 8
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 9 3 5 9 - 3
Stimuli-Responsive Hydrogels for Ophthalmic Drug Delivery covers fundamental aspects in the preparation of polymeric in-situ, stimuli-responsive hydrogels, including propertie… Read more
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Stimuli-Responsive Hydrogels for Ophthalmic Drug Delivery covers fundamental aspects in the preparation of polymeric in-situ, stimuli-responsive hydrogels, including properties, characterization, chemistry, and fabrication of these hydrogels. The book will help the reader select the most appropriate material and design for the desired application. The book goes on to review applications in ophthalmic drug delivery, covering in vitro and in vivo models, animal models, preclinical testing, patents, and more. This is a must-have reference for researchers and academics in the fields of materials science, biomaterials, pharmacology and polymer science, with an interest in clinical aspects of hydrogel design and application.
- Provides step-by-step coverage for engineering in-situ and stimuli-responsive hydrogels, from design, characterization, and toxicity considerations to fabrication, process optimization, and drug release kinetics
- Utilizes an interdisciplinary approach, bringing together authors from pharmacology, polymer science, and medical backgrounds
- Details the advantages and challenges of using stimuli-responsive hydrogels for ophthalmic drug delivery, with a focus on clinical translation
Researchers and postgraduate students in the fields of materials science/biomaterials, biomedical engineering, pharmacology, and tissue engineering
1. Introduction to polymeric in-situ forming hydrogels
2. Biopolymers for in-situ forming hydrogels: synthesis, characterization, and toxicity
3. Chemistry and applications of biopolymer stimuli-responsive in-situ gels
4. Design, engineering, and fabrication of biopolymer in-situ forming hydrogels
5. Process optimization for design and fabrication of biopolymer stimuli-responsive
hydrogels
6. Properties of biopolymeric in-situ hydrogels
7. Swelling and drug release kinetics of biopolymer in-situ forming hydrogels
8. Structural and load-bearing characteristics of biopolymer in-situ forming hydrogels
9. Functionalization of in-situ forming biopolymer hydrogels
Part II: Applications in Ophthalmic Drug Delivery
10. Eye anatomy, physiology, and ocular barriers
11. In vitro and in vivo models in ophthalmic drug delivery
12. Formulation and ocular drug delivery routes
13. Clinical indications of stimuli-responsive hydrogels in ophthalmic drug delivery
14. Natural and synthetic materials for stimuli-responsive hydrogels in ophthalmic drug delivery
15. Characteristics and kinetics of in-situ forming hydrogels in ophthalmic drug delivery
16. Cell-laden stimuli-responsive hydrogels in ophthalmic drug delivery
17. Animal models and preclinical tests for evaluation of stimuli-responsive hydrogels in ophthalmic drug delivery
18. Biopolymer-based in-situ forming hydrogels: from laboratory to practical application
19. Commercially available stimuli-responsive hydrogels for ophthalmic drug delivery
20. Advantages and challenges of biopolymer in-situ hydrogels for ophthalmic drug delivery
21. Patents for biopolymer in-situ hydrogels for ophthalmic drug delivery
- Edition: 1
- Published: May 8, 2024
- Imprint: Woodhead Publishing
- Language: English
DC
Dipankar Chattopadhyay
JO
Jonathan Tersur Orasugh
Dr. Jonathan Tersur Orasugh is currently a postdoctoral researcher at the Department of Chemical Sciences, University of Johannesburg, Doornfontein 2028, Johannesburg, South Africa, and Centre for Nanostructures and Advanced Materials, DSI-CSIR Nanotechnology Innovation Centre, Council for Scientific & Industrial Research, CSIR, Pretoria 0001, South Africa. His research focus is in nanoscience and nanotechnology, Textiles, and Fibres. Presently, Dr. Jonathan is working on EMI shielding materials design and fabrication at CSIR, Pretoria in affiliation with the University of Johannesburg. He has also, carried out successful research work on synthesis of nano crystalline cellulose and its application in edible packaging, transdermal and ophthalmic drug delivery, and published articles in reputed high impact factor scientific journals along with several, presentation at international conferences. Dr. Jonathan has Ph.D. (Nanoscience and Nanotechnology) and MTech (Technical Textiles: Fibre Technology) from University of Calcutta, Kolkata, and B.Tech. (Textile Technology) from Kaduna Polytechnic, Kaduna, Nigeria. He has published more than 10 research articles in diverse international journals along with several books and book chapters with publishers of high repute. He is an active editor with few international journals and a reviewer with different international journals. He has more than 7yrs of research experience in the field of polymer composites and nanocomposites, synthesis, and surface treatment of nanomaterials along with their potential applications. He has carried out industrial-based research at to a satisfactory and implementable stage at the pilot plant scale. He is also an executive board member and research head at EL-YOTEK NIG. LTD. He is also a research consultant with AMER-SIL KETEX PVT LTD., India.
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Anjan Adhikari
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